Search
Search Results
-
Fumarate induces LncRNA-MIR4435-2HG to regulate glutamine metabolism remodeling and promote the development of FH-deficient renal cell carcinoma
Fumarate hydratase (FH) deficient renal cell carcinoma (RCC) is a type of tumor with definite metabolic disorder, but the mechanism of metabolic...
-
ECSIT facilitates memory CD8+ T cell development by mediating fumarate synthesis during viral infection and tumorigenesis
Memory CD8 + T cells play a crucial role in infection and cancer and mount rapid responses to repeat antigen exposure. Although memory cell...
-
Light Regulation of Tricarboxylic Acid Cycle Isoenzymes in Plants
AbstractLight regulation of the tricarboxylic acid cycle (TCA) in green plant leaves is carried out by active forms of phytochrome and cryptochrome...
-
RETRACTED ARTICLE: Suppression of fumarate hydratase activity increases the efficacy of cisplatin-mediated chemotherapy in gastric cancer
Gastric cancer (GC) is one of the most common malignancies worldwide. Due to the low rate of early detection, most GC patients were diagnosed as...
-
Desulfobotulus pelophilus sp. nov., an Alkaliphilic Sulfate-Reducing Bacterium from a Terrestrial Mud Volcano
Abstract —An alkaliphilic, sulfate-reducing, anaerobic bacterium (strain H1 T ) was isolated from a terrestrial mud volcano at the Taman Peninsula,...
-
Sulfurospirillum tamanensis sp. nov., a Facultatively Anaerobic Alkaliphilic Bacterium from a Terrestrial Mud Volcano
Abstract —An alkaliphilic, facultatively anaerobic bacterium (strain T05b T ) was isolated from a terrestrial mud volcano on the Taman Peninsula,...
-
Whole genome sequencing and analysis of selenite-reducing bacteria Bacillus paralicheniformis SR14 in response to different sugar supplements
The biosynthetic process of selenium nanoparticles (SeNPs) by specific bacterial strain, whose growth directly affects the synthesis efficiency, has...
-
Singlet oxygen-induced signalling depends on the metabolic status of the Chlamydomonas reinhardtii cell
Using a mutant screen, we identified trehalose 6-phosphate phosphatase 1 (TSPP1) as a functional enzyme dephosphorylating trehalose 6-phosphate...
-
Changes in S-(2-succinyl)cysteine and advanced glycation end-products levels in mouse tissues associated with aging
Cysteine is non-enzymatically modified by fumarate, which is an intermediate of the tricarboxylic acid cycle, leading to the formation of S -(2-succiny...
-
Physiological and metabolic responses to nitrogen availability of rice (Oryza sativa L.) cultivars with differ in nitrogen efficient
Develo** genotypes with high-nitrogen use efficiency is a prerequisite for achieving sustainable agriculture and high yields. In this study, both...
-
Fumarate hydratase loss promotes mitotic entry in the presence of DNA damage after ionising radiation
An altered response to DNA damage is commonly associated with genomic instability, a hallmark of cancer. Fumarate hydratase (FH) was recently...
-
Recent advances in microbial production of L-malic acid
AbstractOver the last few decades, increasing concerns regarding fossil fuel depletion and excessive CO 2 emissions have led to extensive fundamental...
-
Sulfate-Reducing Prokaryotes: Changing Paradigms
This chapter traces the development of research with sulfate-reducing microorganisms by emphasizing their growth in an array of media. The important...
-
Insights into growth kinetics and roles of enzymes of Krebs’ cycle and sulfur oxidation during exochemolithoheterotrophic growth of Achromobacter aegrifaciens NCCB 38021 on succinate with thiosulfate as the auxiliary electron donor
Achromobacter aegrifaciens NCCB 38021 was grown heterotrophically on succinate versus exochemolithoheterotrophically on succinate with thiosulfate as...
-
Metabolic Modules, Pathways, and Nodes of Intermediates
The prototypic enzymatic reactions introduced in Chap. 7 are shown in this chapter as they combine and function...
-
Metabolic engineering of Shewanella oneidensis to produce glutamate and itaconic acid
AbstractShewanella oneidensis is a gram-negative bacterium known for its unique respiratory capabilities, which allow it to utilize a wide range of...
-
Cytidine deaminase deficiency in tumor cells is associated with sensitivity to a naphthol derivative and a decrease in oncometabolite levels
Identifying new molecular targets for novel anticancer treatments is a major challenge in clinical cancer research. We have shown that cytidine...
-
Mitochondria, Autophagy and Inflammation: Interconnected in Aging
In this manuscript, I discuss the direct link between abnormalities in inflammatory responses, mitochondrial metabolism and autophagy during the...
-
Identification of protein profile in metacyclic and amastigote-like stages of Leishmania tropica: a proteomic approach
Leishmaniasis is a tropical disease that leads to various clinical phenotypes. This study aimed to investigate protein expression changes in...
