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Cytological and genetic effects of rye chromosomes 1RS and 3R on the wheat-breeding founder parent Chuanmai 42 from southwestern China
Rye ( Secale cereale L.) is an important genetic resource for improving the disease resistance of wheat. An increasing number of rye chromosome...
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Conservatively transmitted alleles of key agronomic genes provide insights into the genetic basis of founder parents in bread wheat (Triticum aestivum L.)
BackgroundFounder parents play extremely important roles in wheat breeding. Studies into the genetic basis of founder parents and the transmission...
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Founder cell configuration drives competitive outcome within colony biofilms
Bacteria can form dense communities called biofilms, where cells are embedded in a self-produced extracellular matrix. Exploiting competitive...
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Uncovering gene-family founder events during major evolutionary transitions in animals, plants and fungi using GenEra
We present GenEra ( https://github.com/josuebarrera/GenEra ), a DIAMOND-fueled gene-family founder inference framework that addresses previously...
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Population bottlenecks and founder effects: implications for mosquito-borne arboviral emergence
Transmission of arthropod-borne viruses (arboviruses) involves infection and replication in both arthropod vectors and vertebrate hosts. Nearly all...
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Gene-knockout by iSTOP enables rapid reproductive disease modeling and phenoty** in germ cells of the founder generation
Cytosine base editing achieves C•G-to-T•A substitutions and can convert four codons (CAA/CAG/CGA/TGG) into STOP-codons (induction of STOP-codons,...
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An Amish founder population reveals rare-population genetic determinants of the human lipidome
Identifying the genetic determinants of inter-individual variation in lipid species (lipidome) may provide deeper understanding and additional...
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Founder gene pool composition and genealogical structure in two populations of Austrian Carniolan honey bees (Apis mellifera carnica) as derived from pedigree analysis
Pedigree analyses describing gene pool and genetic diversity frequently have been performed for multiple livestock species. In honey bees, comparable...
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The Newfoundland and Labrador mosaic founder population descends from an Irish and British diaspora from 300 years ago
The founder population of Newfoundland and Labrador (NL) is a unique genetic resource, in part due to its geographic and cultural isolation, where...
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Identification and validation of QTLs for kernel number per spike and spike length in two founder genotypes of wheat
BackgroundKernel number per spike (KNS) and spike length (SL) are important spike-related traits in wheat variety improvement. Discovering genetic...
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Structural variants and tandem repeats in the founder individuals of four F2 pig crosses and implications to F2 GWAS results
BackgroundStructural variants and tandem repeats are relevant sources of genomic variation that are not routinely analyzed in genome wide association...
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Precisely map** a major QTL for grain weight on chromosome 5B of the founder parent Chuanmai42 in the wheat-growing region of southwestern China
Key messageQTgw.saas-5B was validated as a major thousand-grain weight-related QTL in a founder parent used for wheat breeding and then precisely...
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Tracing founder haplotypes of Japanese apple varieties: application in genomic prediction and genome-wide association study
Haplotypes provide useful information for genomics-based approaches, genomic prediction, and genome-wide association study. As a small number of...
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Spectrum of NPHS1 and NPHS2 variants in egyptian children with focal segmental glomerular sclerosis: identification of six novel variants and founder effect
The aim of this study is to screen for variants in NPHS1 and NPHS2 , in a cohort of Egyptian children with steroid-resistant nephrotic syndrome...
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Identification and cross-validation of genetic loci conferring resistance to Septoria nodorum blotch using a German multi-founder winter wheat population
Key messageWe identified allelic variation at two major loci, QSnb.nmbu-2A.1 and QSnb.nmbu-5A.1 , showing consistent and additive effects on SNB...
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Endosymbionts modulate virus effects on aphid-plant interactions
Vector-borne pathogens frequently modify traits of their primary hosts and vectors in ways that influence disease transmission. Such effects can...
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Founder effects, post-introduction evolution and phenotypic plasticity contribute to invasion success of a genetically impoverished invader
Multiple mechanisms may act synergistically to promote success of invasive plants. Here, we tested the roles of three non-mutually exclusive...
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Clonal sector analysis and cell ablation confirm a function for DORNROESCHEN-LIKE in founder cells and the vasculature in Arabidopsis
Main conclusion Inducible lineage analysis and cell ablation via conditional toxin expression in cells expressing the DORNRÖSCHEN-LIKE transcription...
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The natural and human-mediated expansion of a human-commensal lizard into the fringes of Southeast Asia
BackgroundHuman-commensal species often display deep ancestral genetic structure within their native range and founder-effects and/or evidence of...
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Founder cells for hepatocytes during liver regeneration: from identification to application
Liver regeneration (LR) capacity in vertebrates developed through natural selection over a hundred million years of evolution. To maintain...
