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Autophagy induces hair follicle stem cell activation and hair follicle regeneration by regulating glycolysis
BackgroundHair follicle stem cells (HFSCs) typically remain quiescent and are activated only during the transition from telogen to anagen to ensure...
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Tracking Follicle Cell Development
Somatic follicle cells are critical support cells for Drosophila oogenesis, as they provide signals and molecules needed to produce a mature egg....
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Local and systemic mechanisms that control the hair follicle stem cell niche
Hair follicles are essential appendages of the mammalian skin, as hair performs vital functions of protection, thermoregulation and sensation. Hair...
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Ficoll density gradient sedimentation isolation of pelage hair follicle mesenchymal stem cells from adult mouse back skin: a novel method for hair follicle mesenchymal stem cells isolation
BackgroundHair follicle mesenchymal stem cells (HF-MSCs) have great potential for cell therapy. Traditional method to isolate whisker HF-MSC is...
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Progenitor-derived endothelin controls dermal sheath contraction for hair follicle regression
Substantial follicle remodelling during the regression phase of the hair growth cycle is coordinated by the contraction of the dermal sheath smooth...
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Identification and analysis of key circRNAs in the mouse embryonic ovary provides insight into primordial follicle development
BackgroundCircRNAs are a class of noncoding RNAs with tissue- and development-specific expression characteristics. In many mammals, primordial...
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PARP1-catalyzed PARylation of YY1 mediates endoplasmic reticulum stress in granulosa cells to determine primordial follicle activation
Although only a small number of primordial follicles are known to be selectively activated during female reproductive cycles, the mechanisms that...
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Time-course RNA-seq analysis reveals stage-specific and melatonin-triggered gene expression patterns during the hair follicle growth cycle in Capra hircus
BackgroundCashmere goat is famous for its high-quality fibers. The growth of cashmere in secondary hair follicles exhibits a seasonal pattern arising...
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Simulated microgravity reduces quality of ovarian follicles and oocytes by disrupting communications of follicle cells
Ovarian follicles are the fundamental structures that support oocyte development, and communications between oocytes and follicle somatic cells are...
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Hepatocyte growth factor-modified hair follicle stem cells ameliorate cerebral ischemia/reperfusion injury in rats
BackgroundHair follicle stem cells (HFSCs) are considered as a promising cell type in the stem cell transplantation treatment of neurological...
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Cellular Heterogeneity Facilitates the Functional Differences Between Hair Follicle Dermal Sheath Cells and Dermal Papilla Cells: A New Classification System for Mesenchymal Cells within the Hair Follicle Niche
Mesenchymal stem cells (MSCs) are known for their self-renewal and multi-lineage differentiation potential, with these cells often being evaluated in...
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MiR-149-5p promotes β-catenin-induced goat hair follicle stem cell differentiation
The Yangtze River Delta white goat is a unique goat species that can produce superior-quality brush hair. The formation of superior-quality brush...
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P62 promotes FSH-induced antral follicle formation by directing degradation of ubiquitinated WT1
In females, the pathophysiological mechanism of poor ovarian response (POR) is not fully understood. Considering the expression level of p62 was...
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High expression circRALGPS2 in atretic follicle induces chicken granulosa cell apoptosis and autophagy via encoding a new protein
BackgroundThe reproductive performance of chickens mainly depends on the development of follicles. Abnormal follicle development can lead to...
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Effects of hypoxia-preconditioned HucMSCs on neovascularization and follicle survival in frozen/thawed human ovarian cortex transplanted to immunodeficient mice
BackgroundThe massive loss of follicles in the early stage of ovarian tissue transplantation is considered a significant restriction to the efficacy...
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Construction of transcriptome atlas of white yak hair follicle during anagen and catagen using single-cell RNA sequencing
BackgroundAs the direct organ of villus, hair follicles have obvious seasonal cycles. The hair follicle cycle is orchestrated by multiple cell types...
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Comparative immunohistochemical analysis suggests a conserved role of EPS8L1 in epidermal and hair follicle barriers of mammals
The mammalian skin and its appendages depend on tightly coordinated differentiation of epithelial cells. Epidermal growth factor receptor (EGFR)...
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Effect of overexpression of KLF4 on the growth and development of hair follicles in mice
Hair follicle growth is cyclical, and hair cycle dysfunction can lead to hair follicle-related disorders, including alopecia and hirsutism. The...
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GDF9His209GlnfsTer6/S428T and GDF9Q321X/S428T bi-allelic variants caused female subfertility with defective follicle enlargement
BackgroundAntral follicles consist of an oocyte cumulus complex surrounding by somatic cells, including mural granulosa cells as the inner layer and...
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Single-cell profiling reveals transcriptome dynamics during bovine oocyte growth
BackgroundMammalian follicle development is characterized by extensive changes in morphology, endocrine responsiveness, and function, providing the...
