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Effect of Unmetabolized Folic Acid on Immunoinflammatory Markers in Sickle Cell Disease Patients Taking Folic Acid Supplementation
Folic acid (FA) supplementation in sickle cell disease (SCD) patients lead to accumulation of unmetabolized folic acid (UMFA) which might influence...
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Surface Modification of Liposomes Using Folic Acid
Liposomes are usually defined as spherically shaped microscopic vesicles that consist of one or more phospholipid bilayer membranes. They are widely... -
Comparing Effects of Folic Acid, Epibrassinolide, Chitosan and Glutathione Foliar Treatments on Safflower’s Physiology and Yield during Water Stress
AbstractWhile the potential for biostimulants to mitigate water stress holds promise, the underlying physiological mechanisms in safflower ( Carthamus...
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Arginine and Folic Acid Improve Metabolites Content of Tomatillo (Physalis philadelphica) Fruit
AbstractTomatillo ( Physalis philadelphica Lam.) has been interested for its medicinal bioactive compounds, which can be promoted using...
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Role of folic acid in regulating gut microbiota and short-chain fatty acids based on an in vitro fermentation model
AbstractFolic acid deficiency is common worldwide and is linked to an imbalance in gut microbiota. However, based on model animals used to study the...
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Molecular regulatory mechanism of key LncRNAs in subclinical mastitic cows with folic acid supplementation
BackgroundFolic acid is a water-soluble B vitamin (B9), which is closely related to the body’s immune and other metabolic pathways. The folic acid...
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Selenium-Methionine-Folic Acid Nanoparticles (SeMetFa NPs) and Its In Vivo Efficacy Against Rheumatoid Arthritis
Selenium nanoparticles can be beneficial against rheumatoid arthritis, with limitations in dosage formulation due to their toxicity and low...
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Genetic variants of MTHFR gene in relation to folic acid levels and bone mineral density in Polish patients with inflammatory bowel disease
Lower bone mineral density (BMD) constitutes a common issue in inflammatory bowel disease (IBD). Studies often explore the association between BMD...
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Folic acid protects and heals gastric mucosa: role of acid output, inflammatory cytokines, angiogenic and growth factors
BackgroundFolic acid modulates gastrointestinal inflammatory disorders via a number of suggested gastroprotective mechanisms. Gastric acid,...
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Prenatal folic acid and vitamin B12 imbalance alter neuronal morphology and synaptic density in the mouse neocortex
Previous reports have provided evidence that insufficient or excessive maternal folic acid (FA) intake during pregnancy can alter neurodevelopment of...
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Serum concentrations of folic acid and cobalamin and energy metabolism of ewes as a function of the energy density of the diet, peripartum period, and pregnancy toxemia
The aim of this study was to determine the serum levels of folic acid, cobalamin, and indicators of energy metabolism during the peripartum period of...
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Characterization of the Ayran Made with Commercial Probiotic Cultures for Fatty Acids, Cholesterol, Folic Acid Levels, and Anti-Oxidative Potential
Ayran is a salted drinkable fermented milk food which consumed in many countries around the world. In this study, some chemical parameters were...
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Therapeutic Effect of Trigonella foenum-graecum l Seeds Extract on Folic Acid-Induced Acute Kidney Injury
Acute kidney injury (AKI) is a serious clinical illness that produces renal failure quickly and has a high fatality rate. Fenugreek possesses...
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Low Vitamin A Status: A Potential Limiting Factor for Hemoglobin Improvement to Iron–Folic Acid Supplementation in Adolescent Girls with Iron Deficiency Anemia
Iron deficiency anemia (IDA) is a persistent public health challenge in India, particularly among adolescent girls. Despite the use of Iron–Folic...
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Carboxypeptidase G and pterin deaminase metabolic pathways degrade folic acid in Variovorax sp. F1
BackgroundFolic acid (FA) is a synthetic vitamin (B 9 ) and the oxidized form of a metabolic cofactor that is essential for life. Although the...
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Clinico-Etiopathogenesis of Vitamin B12, Folic Acid and Iron Deficiency in Severe Acute Malnutrition Children: A Tertiary Care Hospital Experience from Central India
In severe acute malnutrition, micronutrient deficiency as well as protein energy malnutrition is a major obstacle to growth & development. Iron...
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Hyperhomocysteinemia-related serum metabolome alterations not normalized by short-term folic acid treatment
IntroductionHyperhomocysteinemia (HHCys) is an independent risk factor for various diseases such as cardiovascular diseases, Alzheimer’s, and...
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The role of folic acid in inducing of apoptosis by zinc(II) complex in ovary and cervix cancer cells
AbstractHerein, the synthesis, structure, binding affinity, cytotoxicity, and apoptotic properties of the new Zn(II) complex composed of folic acid...
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Characterization and Anticancer Activity of a Folic Acid Conjugated and Cationic Peptide L-K6 Encapsulated Cancer-Targeting Liposomal Drug Delivery System
Cationic antimicrobial peptides (CAPs) have gained increasing attention in current anti-cancer drugs discovery due to their unique mechanisms of...