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‘Social’ versus ‘asocial’ cells—dynamic competition flux balance analysis
In multicellular organisms cells compete for resources or growth factors. If any one cell type wins, the co-existence of diverse cell types...
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Integration of Metabolomics and Flux Balance Analysis: Applications and Challenges
This book chapter presents an in-depth analysis of the integration of metabolomics and flux balance analysis (FBA) as powerful tools for...
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Predicting microbial interactions with approaches based on flux balance analysis: an evaluation
BackgroundGiven a genome-scale metabolic model (GEM) of a microorganism and criteria for optimization, flux balance analysis (FBA) predicts the...
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Combining denoising of RNA-seq data and flux balance analysis for cluster analysis of single cells
BackgroundSophisticated methods to properly pre-process and analyze the increasing collection of single-cell RNA sequencing (scRNA-seq) data are...
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Fluxomics and Metabolic Flux Analysis
Fluxomics and metabolic flux analysis (MFA) are cutting-edge experimental techniques in a biological system focuses on quantifying the flux of...
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Unveiling evapotranspiration patterns and energy balance in a subalpine forest of the Qinghai–Tibet Plateau: observations and analysis from an eddy covariance system
Evapotranspiration is an important parameter used to characterize the water cycle of ecosystems. To understand the properties of the...
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An improved algorithm for flux variability analysis
Flux balance analysis (FBA) is an optimization based approach to find the optimal steady state of a metabolic network, commonly of microorganisms...
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Flux sampling in genome-scale metabolic modeling of microbial communities
BackgroundMicrobial communities play a crucial role in ecosystem function through metabolic interactions. Genome-scale modeling is a promising method...
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Evaluating the contribution of plant metabolic pathways in the light to the ATP:NADPH demand using a meta-analysis of isotopically non-stationary metabolic flux analyses
Balancing the ATP: NADPH demand from plant metabolism with supply from photosynthesis is essential for preventing photodamage and operating...
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Mechanisms of metabolic adaptation in the duckweed Lemna gibba: an integrated metabolic, transcriptomic and flux analysis
BackgroundDuckweeds are small, rapidly growing aquatic flowering plants. Due to their ability for biomass production at high rates they represent...
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Bioinformatics and metabolic flux analysis highlight a new mechanism involved in lactate oxidation in Clostridium tyrobutyricum
Climate change and environmental issues compel us to find alternatives to the production of molecules of interest from petrochemistry. This study...
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Exploring metabolic effects of dipeptide feed media on CHO cell cultures by in silico model-guided flux analysis
AbstractThere is a growing interest in perfusion or continuous processes to achieve higher productivity of biopharmaceuticals in mammalian cell...
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Droughts impede water balance recovery from fires in the Western United States
A steady rise in fires in the Western United States, coincident with intensifying droughts, imparts substantial modifications to the underlying...
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Analysis of Water Heat Flux and Drought based on Wetland Classification in the Yellow River Delta
To provide scientific basis for utilizing wetland resources, the drought conditions of different wetland types were evaluated in the Yellow River...
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The non-mevalonate pathway requires a delicate balance of intermediates to maximize terpene production
AbstractTerpenes are valuable industrial chemicals whose demands are increasingly being met by bioengineering microbes such as E. coli . Although the...
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Morphological, physiological and carbon balance response of Eucalyptus genotypes under water stress
Water stress is considered one of the main environmental factors that limit survival and productivity of Eucalyptus plantations. Identifying...
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Effects of improved amino acid balance diet on lysine mammary utilization, whole body protein turnover and muscle protein breakdown on lactating sows
BackgroundThe study objective was to test the hypothesis that low crude protein (CP) diet with crystalline amino acids (CAA) supplementation improves...
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Pangenome Flux Balance Analysis Toward Panphenomes
Studies of the pangenome have been empowered by an exponentially increasing amount of strain-specific genome sequencing data. With this data deluge...
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Activating mutations in JAK2 and CALR differentially affect intracellular calcium flux in store operated calcium entry
BackgroundCalcium (Ca 2+ ) signaling regulates various vital cellular functions, including integrin activation and cell migration. Store-operated...
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Hydrologic Measurements and the Water Balance
Most hydrology measurements involving input and output analysis use small catchments because long-term measurement is a feasible proposition. The...