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Effects of Fluoride Toxicity on Female Reproductive System of Mammals: A Meta-Analysis
Considerable integrative efforts have been made to investigate the effects of fluoride on female reproductive organs since the last years. The...
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Role of SIRT1 in Potentially Toxic Trace Elements (Lead, Fluoride, Aluminum and Cadmium) Associated Neurodevelopmental Toxicity
The formation of the central nervous system is a meticulously planned and intricate process. Any modification to this process has the potential to...
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Fluoride-Induced Cortical Toxicity in Rats: the Role of Excessive Endoplasmic Reticulum Stress and Its Mediated Defective Autophagy
The cerebral cortex is closely associated with learning and memory, and fluoride is capable of inducing cortical toxicity, but its mechanism is...
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Fluoride mitigates aluminum-toxicity in barley: morpho-physiological responses and biochemical mechanisms
BackgroundTo our knowledge, the role of exogenous fluoride (F – ) on aluminum (Al)-stress mitigation in plants has not been investigated yet. In this...
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A comparative assessment of fluoride uptake and toxicity in four major crop seedlings: reduction of α-amylase activity and gibberellic acid
Abiotic stresses including fluoride (F − ) affect the quality and quantity of plant growth right from germination. The present study comparatively...
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Fluoride-Induced Mitochondrial Dysfunction and Approaches for Its Intervention
Fluoride is present everywhere in nature. The primary way that individuals are exposed to fluoride is by drinking water. It’s interesting to note...
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Fluoride Toxicity Imposes Differential Reprogramming of the Representative Intermediates and Enzymes Belonging to Nitrogen Metabolism in Two indica Rice Varieties, Varying in their Pattern of Fluoride Stress Response
The main aim of this manuscript was to demonstrate the reprogramming of nitrogen and GABA metabolism in the two rice cultivars (Khitish and MTU1010)...
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Fluoride transport in Arabidopsis thaliana plants is impaired in Fluoride EXporter (FEX) mutants
Fluoride is an environmental toxin prevalent in water, soil, and air. A fluoride transporter called Fluoride EXporter (FEX) has been discovered...
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Impact of Chronic Sodium Fluoride Toxicity on Antioxidant Capacity, Biochemical Parameters, and Histomorphology in Cardiac, Hepatic, and Renal Tissues of Wistar Rats
The study was designed to determine the fluoride distribution after its oral exposure in drinking water and its associated impact on biochemical,...
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Na+/K+ carrier ionophore antibiotics valinomycin and monensin enhance the antibacterial activity of fluoride
Fluoride is routinely used as a highly effective antibacterial agent that interferes with bacterial metabolism through fundamentally different...
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Smart Hesperidin/Chitosan Nanogel Mitigates Apoptosis and Endoplasmic Reticulum Stress in Fluoride and Aluminum-Induced Testicular Injury
Fluoride and aluminum are ubiquitous toxic metals with adverse reproductive effects. The citrus flavonoid hesperidin has protective activities but...
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Combined Effects of Fluoride and Dietary Seleno-L-Methionine at Environmentally Relevant Concentrations on Female Zebrafish (Danio rerio) Liver: Histopathological Damages, Oxidative Stress and Inflammation
Fluoride, a global environmental pollutant, is ubiquitous in aquatic environments and coexists with selenium, which can cause complex effects on...
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Impact of Fluoride Exposure on Rat Placenta: Foetal/Placental Morphometric Alterations and Decreased Placental Vascular Density
Inorganic fluoride is a geogenic and anthropogenic contaminant widely distributed in the environment and commonly identified in contaminated...
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ERS Mediated by GRP-78/PERK/CHOP Signaling Is Involved in Fluoride-Induced Ameloblast Apoptosis
Fluoride can be widely ingested from the environment, and its excessive intake could result in adverse effects. Dental fluorosis is an early sign of...
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Effect of Silicon on the Biochemical and Physiological Attributes of Wheat Under Fluoride Stress
The purpose of the current study was to evaluate the alleviating effect of silicon (Si) on fluoride (F)-mediated toxicity in wheat cultivars.
The...
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Chronic Fluoride Exposure Induces Ovarian Dysfunction and Potential Association with Premature Ovarian Failure in Female Rats
Chronic fluorosis has been widely investigated for its adverse effects on skeletal and neurological health; however, its impact on reproductive...
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Fluoride Induces Neurocytotoxicity by Disrupting Lysosomal Iron Metabolism and Membrane Permeability
The detrimental effects of fluoride on neurotoxicity have been widely recorded, yet the detailed mechanisms underlying these effects remain unclear....
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Effect of Excess Fluoride Exposure on Radiographic and Histopathological Changes in Long Bones of Rabbit
The present study aimed to investigate the effects of excess fluoride exposure on long bones in young rabbits ( Oryctolagus cuniculus ). New Zealand...
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Fluoride Induced Neurobehavioral Impairments in Experimental Animals: a Brief Review
Fluoride is one of the major toxicants in the environment and is often found in drinking water at higher concentrations. Living organisms including...
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Clofibrate, a Peroxisome Proliferator–Activated Receptor-Alpha (PPARα) Agonist, and Its Molecular Mechanisms of Action against Sodium Fluoride–Induced Toxicity
Sodium fluoride (NaF) is one of the neglected environmental pollutants. It is ubiquitously found in the soil, water, and environment. Interestingly,...