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Fatty Acid Profiling of Grapevine Extracellular Compartment
The apoplast is the plant compartment present between the plasma membrane and the cuticle, comprised of the cell wall and the extracellular spaces...
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In Vivo Imaging of Bone Marrow Long-Chain Fatty Acid Uptake
In vivo imaging enables the detection and visualization of many different processes occurring within the body. Fatty acid uptake is a fundamental...
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Inhibition of fatty acid uptake by TGR5 prevents diabetic cardiomyopathy
Diabetic cardiomyopathy is characterized by myocardial lipid accumulation and cardiac dysfunction. Bile acid metabolism is known to play a crucial...
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Fatty acid metabolism of immune cells: a new target of tumour immunotherapy
Metabolic competition between tumour cells and immune cells for limited nutrients is an important feature of the tumour microenvironment (TME) and is...
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Proteolytic activation of fatty acid synthase signals pan-stress resolution
Chronic stress and inflammation are both outcomes and major drivers of many human diseases. Sustained responsiveness despite mitigation suggests a...
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Discovery biomarker to optimize obeticholic acid treatment for non-alcoholic fatty liver disease
The response rate to obeticholic acid (OCA), a potential therapeutic agent for non-alcoholic fatty liver disease, is limited. This study demonstrated...
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The role of fatty acid metabolism in acute lung injury: a special focus on immunometabolism
Reputable evidence from multiple studies suggests that excessive and uncontrolled inflammation plays an indispensable role in mediating, amplifying,...
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Arf1 coordinates fatty acid metabolism and mitochondrial homeostasis
Lipid mobilization through fatty acid β-oxidation is a central process essential for energy production during nutrient shortage. In yeast, this...
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Transcriptome analyses of Acer Truncatum Bunge seeds to delineate the genes involved in fatty acid metabolism
BackgroundAcer truncatum Bunge is an economic, ecological, oil, and medicinal tree, and its kernel oil is rich in nervonic acid. It is crucial to...
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Improving fatty acid composition of soybean yield under NaCl stress by soaking seeds in ascorbate
The present study aimed to improve the fatty acid composition of soybean seeds (Giza 82) grown under salinity using ascorbate (AsA). To achieve this...
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Deconvolving feeding niches and strategies of abyssal holothurians from their stable isotope, amino acid, and fatty acid composition
Holothurians are the dominant megabenthic deposit feeders in the Peru Basin (SE Pacific) and feed to various degrees of selectivity on a heterogenous...
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Fatty acid oxidation organizes mitochondrial supercomplexes to sustain astrocytic ROS and cognition
Having direct access to brain vasculature, astrocytes can take up available blood nutrients and metabolize them to fulfil their own energy needs and...
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Fish oil replacement with different vegetable oils in Onychostoma macrolepis: Effects on fatty acid metabolism based on whole-body fatty acid balance method and genes expression
To evaluate the fatty acid (FA) metabolism status and possibility as a DHA source of farmed Onychostoma macrolepis , a total of 168 fish (2.03 ± 0.23...
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Dysregulated palmitic acid metabolism promotes the formation of renal calcium-oxalate stones through ferroptosis induced by polyunsaturated fatty acids/phosphatidic acid
The pathogenesis of renal calcium-oxalate (CaOx) stones is complex and influenced by various metabolic factors. In parallel, palmitic acid (PA) has...
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Fatty acid profiles and stable isotope composition of Antarctic macroalgae: a baseline for a combined biomarker approach in food web studies
The Western Antarctic Peninsula supports a diverse assemblage of > 100 described macroalgal species that contribute to the base of coastal food webs,...
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Bioproduction of n-3 polyunsaturated fatty acids by nematode fatty acid desaturases and elongase in Drosophila melanogaster
n-3 polyunsaturated fatty acids (n-3 PUFAs), including α-linolenic acid and eicosapentaenoic acid (EPA), are essential nutrients for vertebrates...
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Membrane fatty acid desaturase: biosynthesis, mechanism, and architecture
AbstractFatty acid desaturase catalyzes the desaturation reactions by inserting double bonds into the fatty acyl chain, producing unsaturated fatty...
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Characterization of free fatty acid receptor family in rainbow trout (Oncorhynchus mykiss): towards a better understanding of their involvement in fatty acid signalisation
Since 20 years of research, free fatty acids receptors (FFARs) have received considerable attention in mammals. To date, four FFARs (FFAR1, FFAR2,...
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Fatty acid metabolism-related molecular subtypes and a novel model for predicting prognosis in bladder cancer patients
This study aims to develop fatty acid metabolism-related molecular subtypes and construct a fatty acid metabolism-related novel model for bladder...
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Fatty Acid Profile and Mineral Composition of Red-Toothed Triggerfish (Odonus niger) Landed in Karnataka, Southeastern Arabian Sea
The seasonal and sex-wise variations in fatty acid and mineral composition in the tissue of Odonus niger collected from the Karnataka coast,...