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Variation of fatty acid composition in different tissues during Astragalus membranaceus seedling morphogenesis
Morphogenesis is a critical stage for the successful seedling establishment, which relies on energy provided by seed storage. Lipids are utilized as...
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The structural basis of fatty acid elongation by the ELOVL elongases
Very long chain fatty acids (VLCFAs) are essential building blocks for the synthesis of ceramides and sphingolipids. The first step in the fatty acid...
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Fatty Acid Synthase: Structure, Function, and Regulation
Fatty acid (FA) biosynthesis plays a central role in the metabolism of living cells as building blocks of biological membranes, energy reserves of...
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Review: genetic background of milk fatty acid synthesis in bovines
Milk fat composition is an important trait for the dairy industry as it directly influences the nutritional and technological properties of milk and...
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Fatty acid metabolism changes in association with neurobehavioral deficits in animal models of fetal alcohol spectrum disorders
Fetal alcohol spectrum disorders (FASD) show behavioral problems due to prenatal alcohol exposure (PAE). A previous study reports changes in gene...
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Transcriptome analyses of Acer Truncatum Bunge seeds to delineate the genes involved in fatty acid metabolism
BackgroundAcer truncatum Bunge is an economic, ecological, oil, and medicinal tree, and its kernel oil is rich in nervonic acid. It is crucial to...
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Fish oil replacement with different vegetable oils in Onychostoma macrolepis: Effects on fatty acid metabolism based on whole-body fatty acid balance method and genes expression
To evaluate the fatty acid (FA) metabolism status and possibility as a DHA source of farmed Onychostoma macrolepis , a total of 168 fish (2.03 ± 0.23...
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The physiological and pathological properties of Mead acid, an endogenous multifunctional n-9 polyunsaturated fatty acid
Mead acid (MA, 5,8,11-eicosatrienoic acid) is an n-9 polyunsaturated fatty acid (PUFA) and a marker of essential fatty acid deficiency, but...
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Microbial Biofactories: A Promising Approach Towards Sustainable Omega-3 Fatty Acid Production
Omega-3 fatty acids or polyunsaturated fatty acids known as are indispensable to human health and are more commonly referred to as “healthy fats.”...
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The role of fatty acid metabolism in acute lung injury: a special focus on immunometabolism
Reputable evidence from multiple studies suggests that excessive and uncontrolled inflammation plays an indispensable role in mediating, amplifying,...
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Dysregulated palmitic acid metabolism promotes the formation of renal calcium-oxalate stones through ferroptosis induced by polyunsaturated fatty acids/phosphatidic acid
The pathogenesis of renal calcium-oxalate (CaOx) stones is complex and influenced by various metabolic factors. In parallel, palmitic acid (PA) has...
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Membrane fatty acid desaturase: biosynthesis, mechanism, and architecture
AbstractFatty acid desaturase catalyzes the desaturation reactions by inserting double bonds into the fatty acyl chain, producing unsaturated fatty...
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Bioproduction of n-3 polyunsaturated fatty acids by nematode fatty acid desaturases and elongase in Drosophila melanogaster
n-3 polyunsaturated fatty acids (n-3 PUFAs), including α-linolenic acid and eicosapentaenoic acid (EPA), are essential nutrients for vertebrates...
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Deconvolving feeding niches and strategies of abyssal holothurians from their stable isotope, amino acid, and fatty acid composition
Holothurians are the dominant megabenthic deposit feeders in the Peru Basin (SE Pacific) and feed to various degrees of selectivity on a heterogenous...
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PCYT1A deficiency disturbs fatty acid metabolism and induces ferroptosis in the mouse retina
BackgroundInherited retinal dystrophies (IRDs) are a group of debilitating visual disorders characterized by the progressive degeneration of...
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Characterization of free fatty acid receptor family in rainbow trout (Oncorhynchus mykiss): towards a better understanding of their involvement in fatty acid signalisation
Since 20 years of research, free fatty acids receptors (FFARs) have received considerable attention in mammals. To date, four FFARs (FFAR1, FFAR2,...
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Weighted gene co-expression network analysis identified hub genes critical to fatty acid composition in Gushi chicken breast muscle
BackgroundThe composition and content of fatty acids in the breast muscle are important factors influencing meat quality. In this study, we...
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Determination of dietary essential fatty acids in a deep-sea fish, the splendid alfonsino Beryx splendens: functional characterization of enzymes involved in long-chain polyunsaturated fatty acid biosynthesis
The splendid alfonsino Beryx splendens is a commercially important deep-sea fish in East Asian countries. Because the wild stock of this species has...
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Fern Fatty Acids: From Diversity to Dietary Value
Fatty acids are essential components of all living cells and play vital functions in plant and animal organisms. Literature data demonstrate a...
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Lifespan-extending interventions induce consistent patterns of fatty acid oxidation in mouse livers
Aging manifests as progressive deteriorations in homeostasis, requiring systems-level perspectives to investigate the gradual molecular dysregulation...
