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Characterization and genetic analysis of extensively drug-resistant hospital acquired Pseudomonas aeruginosa isolates
BackgroundThe incidence of hospital-acquired infections in extensively drug-resistant Pseudomonas aeruginosa (XDR-PA) has been increasing worldwide...
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Pathogenicity, resistance patterns, virulence traits, and resistance genes of re-emerging extensively drug-resistant (XDR) Aeromonas veronii in Oreochromis niloticus
Aeromonas veronii , a threatening fish pathogen, is implicated in food-borne infections in humans, contributing to substantial economic losses in the...
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Antibiotic Resistance Profile, Multidrug-, Extensively drug-, and Pandrug-Resistant Bacterial Isolates: Hemagglutination and Hemolytic Activities against Human Erythrocytes
The classification of bacteria as multidrug-resistant (MDR), extensively drug-resistant (XDR), and pandrug-resistant (PDR) are epidemiologically...
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Molecular Characteristics and Genetic Analysis of Extensively Drug-Resistant Isolates with different Tn3 Mobile Genetic Elements
Extensively drug-resistant (XDR) bacteria are the main caues for causing clinical infectious diseases. Our aim was to distinguish the present...
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High Rates of Extensively Drug-Resistant Pseudomonas aeruginosa in Children with Cystic Fibrosis
Pseudomonas aeruginosa has a high adaptive capacity, favoring the selection of antibiotic-resistant strains, which are currently considered a global...
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Bacteriophage as a Novel Therapeutic Weapon for Killing Colistin-Resistant Multi-Drug-Resistant and Extensively Drug-Resistant Gram-Negative Bacteria
Colistin-resistant multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria are highly lethal and many...
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High frequency of carbapenemase in extensively drug-resistant Acinetobacter baumannii isolates in central Iran
ObjectivesWe assessed the frequency of occurrence for infections caused by wild-type A. baumannii , multidrug-resistant (MDR) or XDR A. baumannii ,...
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Comparative genomics of an extensively drug resistant strain Klebsiella pneumoniae IITR008 with international high-risk clonal lineage ST147 isolated from river water
Carbapenem resistant Klebsiella pneumoniae causing severe infection resulting in morbidity and mortality have become a global health concern. K....
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Long-term occurrence of multiple antimicrobial drug resistant Klebsiella pneumoniae isolates harboring virulent potential in a tertiary hospital from Brazil
Klebsiella pneumoniae strains are globally associated with a plethora of opportunistic and severe human infections and are known to spread genes...
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High prevalence of extensively drug resistant and extended spectrum beta lactamases (ESBLs) producing uropathogenic Escherichia coli isolated from Faisalabad, Pakistan
Urinary tract infections (UTIs) are predominantly caused by uropathogenic Escherichia coli ( E. coli ). There is rapid increase in antimicrobial...
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Antimicrobial peptide-loaded decellularized placental sponge as an excellent antibacterial skin substitute against XDR clinical isolates
Post-wound infections have remained a serious threat to society and healthcare worldwide. Attempts are still being made to develop an ideal...
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Resistance profiles, virulence and antimicrobial resistance genes of XDR S. Enteritidis and S. Typhimurium
Avian salmonellosis is concomitant with high financial crises in the poultry industry as well as food-borne illness in man. The present study is...
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Propranolol restores susceptibility of XDR Gram-negative pathogens to meropenem and Meropenem combination has been evaluated with either tigecycline or amikacin
BackgroundInfection with extensive-drug-resistant (XDR) carbapenem-resistant (CR) Gram-negative bacteria (GNB) are viewed as a serious threat to...
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Drug-resistant tuberculosis: a persistent global health concern
Drug-resistant tuberculosis (TB) is estimated to cause 13% of all antimicrobial resistance-attributable deaths worldwide and is driven by both...
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Comparative genomics of drug-resistant strains of Mycobacterium tuberculosis in Ecuador
BackgroundTuberculosis is a serious infectious disease affecting millions of people. In spite of efforts to reduce the disease, increasing antibiotic...
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Mutation detection and minimum inhibitory concentration determination against linezolid and clofazimine in confirmed XDR-TB clinical isolates
BackgroundThe emergence of multidrug-resistant tuberculosis (MDR-TB) has complicated the situation due to the decline in potency of second-line...
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Photodynamic Therapy and Its Synergism with Melittin Against Drug-Resistant Acinetobacter baumannii Isolates with High Biofilm Formation Ability
Drug-resistant biofilm producer A. baumannii isolates are a global concern that warns researchers about the development of new treatments. This study...
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Pyrazinamide Analogs Designed for Rational Drug Designing Strategies against Resistant Tuberculosis
AbstractTuberculosis (TB) is a granulomatous infection that is still the biggest cause of death across the world. TB is a leading cause of death...
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Novel Antimicrobial Peptide SAAP Mutant as a Better Adjuvant to Sulbactam-Based Treatments Against Clinical Strains of XDR Acinetobacter baumannii
The production of extended spectrum β-lactamases (ESBLs) in extensively drug-resistant (XDR) strains of Acinetobacter baumannii has created havoc...
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Evaluation of ethanol and EDTA concentrations in the expression of biofilm-producing smf-1, rpfF genes in XDR clinical isolates of Stenotrophomonas maltophilia
BackgroundStenotrophomonas maltophilia is able to cause infections in immunocompromised patients, and the treatment of this opportunistic pathogen...
