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Characterization and genetic analysis of extensively drug-resistant hospital acquired Pseudomonas aeruginosa isolates
BackgroundThe incidence of hospital-acquired infections in extensively drug-resistant Pseudomonas aeruginosa (XDR-PA) has been increasing worldwide...
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Antibiotic Resistance Profile, Multidrug-, Extensively drug-, and Pandrug-Resistant Bacterial Isolates: Hemagglutination and Hemolytic Activities against Human Erythrocytes
The classification of bacteria as multidrug-resistant (MDR), extensively drug-resistant (XDR), and pandrug-resistant (PDR) are epidemiologically...
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Molecular Characteristics and Genetic Analysis of Extensively Drug-Resistant Isolates with different Tn3 Mobile Genetic Elements
Extensively drug-resistant (XDR) bacteria are the main caues for causing clinical infectious diseases. Our aim was to distinguish the present...
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High Rates of Extensively Drug-Resistant Pseudomonas aeruginosa in Children with Cystic Fibrosis
Pseudomonas aeruginosa has a high adaptive capacity, favoring the selection of antibiotic-resistant strains, which are currently considered a global...
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Comparative genomics of an extensively drug resistant strain Klebsiella pneumoniae IITR008 with international high-risk clonal lineage ST147 isolated from river water
Carbapenem resistant Klebsiella pneumoniae causing severe infection resulting in morbidity and mortality have become a global health concern. K....
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Bacteriophage as a Novel Therapeutic Weapon for Killing Colistin-Resistant Multi-Drug-Resistant and Extensively Drug-Resistant Gram-Negative Bacteria
Colistin-resistant multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria are highly lethal and many...
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High prevalence of extensively drug resistant and extended spectrum beta lactamases (ESBLs) producing uropathogenic Escherichia coli isolated from Faisalabad, Pakistan
Urinary tract infections (UTIs) are predominantly caused by uropathogenic Escherichia coli ( E. coli ). There is rapid increase in antimicrobial...
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Pathogenicity, resistance patterns, virulence traits, and resistance genes of re-emerging extensively drug-resistant (XDR) Aeromonas veronii in Oreochromis niloticus
Aeromonas veronii , a threatening fish pathogen, is implicated in food-borne infections in humans, contributing to substantial economic losses in the...
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High frequency of carbapenemase in extensively drug-resistant Acinetobacter baumannii isolates in central Iran
ObjectivesWe assessed the frequency of occurrence for infections caused by wild-type A. baumannii , multidrug-resistant (MDR) or XDR A. baumannii ,...
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Drug-resistant tuberculosis: a persistent global health concern
Drug-resistant tuberculosis (TB) is estimated to cause 13% of all antimicrobial resistance-attributable deaths worldwide and is driven by both...
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Bactericidal activity of silver nanoparticles in drug-resistant bacteria
Bacterial resistance to multiple drugs is a worldwide problem that afflicts public health. Various studies have shown that silver nanoparticles are...
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Long-term occurrence of multiple antimicrobial drug resistant Klebsiella pneumoniae isolates harboring virulent potential in a tertiary hospital from Brazil
Klebsiella pneumoniae strains are globally associated with a plethora of opportunistic and severe human infections and are known to spread genes...
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Antibiotic-Peptide Conjugation Against Multi-drug Resistant Pathogens: A Comprehensive Review for Therapeutics and Drug Delivery Strategies
A global public health crisis has been created by the emergence of serious infectious illnesses, the rising prevalence of infections that are...
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A Profile of Drug-Resistant Mutations in Mycobacterium tuberculosis Isolates from Guangdong Province, China
Guangdong Province, China’s largest economy, has a high incidence of tuberculosis (TB). At present, there are few reports on the distribution,...
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Pyrazinamide Analogs Designed for Rational Drug Designing Strategies against Resistant Tuberculosis
AbstractTuberculosis (TB) is a granulomatous infection that is still the biggest cause of death across the world. TB is a leading cause of death...
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Drug-Resistant Epithelial Ovarian Cancer: Current and Future Perspectives
Epithelial ovarian cancer (EOC) is a complex disease with diverse histological subtypes, which, based on the aggressiveness and course of disease...
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Mechanism and bioinformatics analysis of the effect of berberine-enhanced fluconazole against drug-resistant Candida albicans
Biofilms produced by Candida albicans present a challenge in treatment with antifungal drug. Enhancing the sensitivity to fluconazole (FLC) is a...
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Virulent and Multi-drug-Resistant Edwardsiella tarda Infection in Oscar Fish: Unveiling the Threat of Mass Mortality and AMR Dissemination
The Oscar fish ( Astronotus ocellatus ) is among the most commonly domesticated and exported ornamental fish species from Kerala. The ornamental fish...
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Prediction of Potential Drug Targets and Vaccine Candidates Against Antibiotic-Resistant Pseudomonas aeruginosa
Pseudomonas aeruginosa is one of the leading causes of nosocomial infections, characterized by increasing antibiotic resistance, severity and...
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Association between biomarkers of inflammation and dyslipidemia in drug resistant tuberculosis in Uganda
BackgroundActive tuberculosis (TB) significantly increases the risk of cardiovascular disease, but the underlying mechanisms remain unclear. This...