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Preventive and Therapeutic Potential of Streptococcus cristatus CA119 in Experimental Periodontitis in Rats
Periodontitis is an inflammatory condition of the oral cavity caused by a mixed infection of various bacteria, which not only severely affects the...
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Unraveling ferroptosis in osteogenic lineages: implications for dysregulated bone remodeling during periodontitis progression
Periodontitis is a highly prevalent disease characterized by inflammation and destruction of tooth-supporting tissues that leads to tooth loss in...
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Infrared laser therapy decreases systemic oxidative stress and inflammation in hypercholesterolemic mice with periodontitis
BackgroundNear-infrared irradiation photobiomodulation (NIR-PBM) has been successfully used in periodontal treatment as an adjuvant tool to locally...
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TRPC expression in human periodontal ligament cells and the periodontal tissue of periodontitis mice: a preliminary study
BackgroundTransient receptor potential canonical (TRPC) channels are non-selective cationic channels with permeability to Ca 2+ and Na + . Despite...
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Does crocin create new hope for the treatment of oral problems? A focus on periodontitis
According to the World Health Organization (WHO) reports, oral health has an indispensable role in the maintenance of human public health. However,...
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Periodontitis salivary microbiota exacerbates colitis-induced anxiety-like behavior via gut microbiota
The gut–brain axis is a bidirectional communication system between the gut and central nervous system. Many host-related factors can affect gut...
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Licochalcone B, a natural anti-inflammatory agent, inhibits the inflammatory response and oxidative stress of periodontal ligament cells in periodontitis
BackgroundPeriodontitis is a multi-microbial infection characterized by a destructive inflammatory process that affects periodontal tissues. The...
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Inflammatory Biomarkers in Periodontitis and Their Effect on the Stem/Progenitor Cells: Molecular Basis of Bone Resorption and Bone Regeneration
Periodontitis is considered one of the most chronic inflammatory diseases damaging the soft and hard tissues supporting the teeth. In periodontitis,...
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Analysis of Experimental Ligature-Induced Periodontitis Model in Mice
Periodontitis is one of the most prevalent chronic inflammatory diseases in humans. However, the disease has been hard to study, majorly because it...
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Therapeutic effects of peptide P140 in a mouse periodontitis model
In our search for innovative drugs that could improve periodontal treatment outcomes, autophagy and its anomalies represent a potential target for...
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CRISPR/Cas13d targeting GZMA in PARs pathway regulates the function of osteoclasts in chronic apical periodontitis
Chronic apical periodontitis is a prevalent oral disease characterized by bone loss, and its underlying mechanisms remain unclear. This study aimed...
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Salivary microbial shifting in hypertensive patients with chronic periodontitis after scaling and root surface debridement
ObjectivesThis study aimed to evaluate the impact of scaling and root surface debridement (SRP) on salivary bacterial counts and systolic and...
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Nitrate and a nitrate-reducing Rothia aeria strain as potential prebiotic or synbiotic treatments for periodontitis
A few studies indicate that nitrate can reduce dysbiosis from a periodontitis point of view. However, these experiments were performed on samples...
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LncRNA00638 promotes the osteogenic differentiation of periodontal mesenchymal stem cells from periodontitis patients under static mechanical strain
BackgroundThe osteogenic differentiation capacity of periodontal mesenchymal stem cells (PDLSCs) can be influenced by different levels of static...
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Dysbiosis and Predicted Functions of the Dental Biofilm of Dairy Goats with Periodontitis
Periodontitis is a polymicrobial biofilm-induced inflammatory disease associated with a dysbiotic microbial community and severely affects the health...
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Inflammatory Biomarkers in Periodontitis and Their Effect on the Stem/Progenitor Cells: Molecular Basis of Bone Resorption and Bone Regeneration
Periodontitis is considered one of the most chronic inflammatory diseases damaging the soft and hard tissues supporting the teeth. In periodontitis,...
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Oral microbial extracellular DNA initiates periodontitis through gingival degradation by fibroblast-derived cathepsin K in mice
Periodontitis is a highly prevalent disease leading to uncontrolled osteoclastic jawbone resorption and ultimately edentulism; however, the disease...
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Periapical bacterial disinfection is critical for dental pulp regenerative cell therapy in apical periodontitis in dogs
BackgroundApplication of pulp regenerative cell therapy for mature teeth with periapical lesions is a critical clinical challenge. The bacterial...
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Exploration of the underlying comorbidity mechanism in psoriasis and periodontitis: a bioinformatics analysis
BackgroundIncreasing evidence indicates that psoriasis (PSO) and periodontitis (PD) are likely to occur together, however, the underlying mechanism...
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The rationale and potential for using Lactobacillus in the management of periodontitis
Periodontitis refers to a wide range of the inflammatory conditions of supporting dental structures. For some patients with periodontitis,...