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Effect of Estradiol on Carbohydrate-Fat Metabolism and FGF21 System Activity in Female C57BL/6 Mice with Short-Term Consumption of the Cafeteria Diet
AbstractThe cafeteria diet contributes to the development of obesity and metabolic syndrome, reduces insulin sensitivity and glucose tolerance....
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β-Estradiol Improves Response of Potato Genotypes to Salt Stress and Enhances Microtuber Production Under In Vitro Conditions
Exogenic application of β-estradiol as a steroidal hormone stimulates cell division, embryo development, callus growth, and stress tolerance in...
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Cellular, Biophysical and in Silico Binding Study of β-Estradiol-6-one 6- (O-carboxy methyl Oxime) with Tubulin in Search of Antimitotic Derivative of 2-Methoxy Estradiol
The tubulin-microtubule system is a major target for a variety of small molecules which can interfere in cell cycle progression. Therefore, it serves...
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Assessing tolerability and physiological responses to 17α-estradiol administration in male rhesus macaques
17α-estradiol has recently been shown to extend healthspan and lifespan in male mice through multiple mechanisms. These benefits occur in the absence...
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Lipopolysaccharide alters CEBPβ signaling and reduces estradiol production in bovine granulosa cells
BackgroundBacterial infection of the uterus in postpartum dairy cows limits ovarian follicle growth, reduces blood estradiol concentrations, and...
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Modulation of neural gene networks by estradiol in old rhesus macaque females
The postmenopausal decrease in circulating estradiol (E2) levels has been shown to contribute to several adverse physiological and psychiatric...
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Exploring the possible role of estradiol in the regulation of reproductive phase-dependent expression of NOD-like receptors in female Channa punctata
Inflammatory responses are modulated by sex steroids, and hence, not surprisingly, in seasonally breeding organisms, the immune responses are...
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ZnT 9 Involvement in Estradiol-Modulated Zinc Homeostasis of the Human Follicular Microenvironment
Female subfertility has been a growing concern for reproductive health. Assisted reproductive technologies make pregnancy possible, but the outcome...
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Systemic metabolic benefits of 17α-estradiol are not exclusively mediated by ERα in glutamatergic or GABAergic neurons
17α-Estradiol (17αE2), a less-feminising enantiomer of 17β-estradiol, has been shown to prolong lifespan and improve metabolic health in a...
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Efficient removal of endocrine disrupting compounds 17 α-ethynyl estradiol and 17 β-estradiol by Enterobacter sp. strain BHUBP7 and elucidation of the degradation pathway by HRAMS analysis
Owing to the increased population and their overuse, estrogens are being detected in the environment at alarming levels. They act as endocrine...
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Higher testosterone and testosterone/estradiol ratio in men are associated with decreased Pheno-/GrimAge and DNA-methylation based PAI1
Sex hormones are hypothesized to drive sex-specific health disparities. Here, we study the association between sex steroid hormones and DNA...
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Oxidized dietary lipids induce vascular inflammation and atherogenesis in post-menopausal rats: estradiol and selected antihyperlipidemic drugs restore vascular health in vivo
BackgroundThermoxidation of edible oil through deep fat frying results in the generation of several oxidized products that promote lipid peroxidation...
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Interaction of estradiol and renin–angiotensin system with microRNAs-21 and -29 in renal fibrosis: focus on TGF-β/smad signaling pathway
Kidney fibrosis is one of the complications of chronic kidney disease (CKD (and contributes to end-stage renal disease which requires dialysis and...
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Correlation Between Estrogen Receptor α Gene Polymorphism (c454-397T>C) with Serum Estradiol Levels and Known Risk Factors in Patients with Myocardial Infarction
Myocardial infarction (MI) remains the most common cause of cardiac failure and continuous increasing rate of morbidity and mortality. We aimed to...
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YB-1 Protein Prevents Age-Related Decline in Plasma Estradiol in Aging Female 5xFAD Transgenic Mice
AbstractAlzheimer’s disease (AD) is an incurable neurodegenerative disease that is the main cause of dementia in the elderly. When looking for new...
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Estradiol mitigates stress-induced cardiac injury and inflammation by downregulating ADAM17 via the GPER-1/PI3K signaling pathway
Stress-induced cardiovascular diseases characterized by inflammation are among the leading causes of morbidity and mortality in postmenopausal women...
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Induction of precocious females in the protandrous barramundi (Lates calcarifer) with long-acting estradiol implants
With the growing demand for fish protein, more aquatic species are currently being introduced into aquaculture. A relatively new cultivar is the...
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Estrogen receptor alpha mediates 17β-estradiol, up-regulates autophagy and alleviates hydrogen peroxide-induced vascular senescence
Atherosclerosis threatens human health by develo** cardiovascular diseases, the deadliest disease world widely. The major mechanism contributing to...
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Ionizing radiation downregulates estradiol synthesis via endoplasmic reticulum stress and inhibits the proliferation of estrogen receptor-positive breast cancer cells
Breast cancer is a major threat to women’s health and estrogen receptor-positive (ER + ) breast cancer exhibits the highest incidence among these...
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Effect of Epinephrine, Norepinephrine, and Estradiol on Persister Formation in the Cultures of Staphylococci from the Human Microbiota and Their Resistance to Starvation and New Medium Stresses
Effects of the human hormones and human microbiota on the growth of symbiotrophic and saprotrophic bacteria are well-known. However, no information...
