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NF-κB signaling in neoplastic transition from epithelial to mesenchymal phenotype
NF-κB transcription factors are critical regulators of innate and adaptive immunity and major mediators of inflammatory signaling. The NF-κB...
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Identification of mesenchymal-to-epithelial transition during heart regeneration through genetic lineage tracing
The epicardium is the important outermost mesothelial/epithelial layer of the heart that serves as a signaling center for cardiac development and...
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Comprehensive molecular interaction map of TGFβ induced epithelial to mesenchymal transition in breast cancer
Breast cancer is one of the prevailing cancers globally, with a high mortality rate. Metastatic breast cancer (MBC) is an advanced stage of cancer,...
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TGFβ2 mediates oxidative stress–induced epithelial-to-mesenchymal transition of bladder smooth muscle
Bladder outlet obstruction (BOO) is the primary clinical manifestation of benign prostatic hyperplasia, the most common urinary system disease in...
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MiR-326-mediated overexpression of NFIB offsets TGF-β induced epithelial to mesenchymal transition and reverses lung fibrosis
Idiopathic Pulmonary Fibrosis (IPF) is a progressively fatal and incurable disease characterized by the loss of alveolar structures, increased...
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An epithelial-to-mesenchymal transition induced extracellular vesicle prognostic signature in non-small cell lung cancer
Despite significant therapeutic advances, lung cancer remains the leading cause of cancer-related death worldwide
1 . Non-small cell lung cancer...
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Visualizing Dynamic Changes During TGF-β-Induced Epithelial to Mesenchymal Transition
Epithelial to mesenchymal transition (EMT) is crucial during embryonic development, tissue fibrosis, and cancer progression. Epithelial cells that...
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Autophagy caused by oxidative stress promotes TGF-β1-induced epithelial-to-mesenchymal transition in human peritoneal mesothelial cells
Epithelial-to-mesenchymal transition (EMT) is one of the main causes of peritoneal fibrosis. However, the pathophysiological mechanisms of EMT,...
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Epithelial-to-mesenchymal transition status correlated with ultrastructural features, and TP53 mutation in patient-derived oral cancer cell lines
BackgroundOral Squamous Cell Carcinoma (OSCC) is a highly prevalent cancer in the Indian subcontinent. The major cause of mortality in OSCC patients...
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The Epithelial-to Mesenchymal Transition Methods and Protocols
This volume details a comprehensive range of methods for imaging epithelial-to-mesechymal transition (EMT)/MET in in vivo systems, and methods to...
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Integrin β4 induced epithelial-to-mesenchymal transition involves miR-383 mediated regulation of GATA6 levels
BackgroundThe process of transdifferentiating epithelial cells to mesenchymal-like cells (EMT) involves cells gradually taking on an invasive and...
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PHF13 epigenetically activates TGFβ driven epithelial to mesenchymal transition
Epigenetic alteration is a pivotal factor in tumor metastasis. PHD finger protein 13 (PHF13) is a recently identified epigenetic reader of H3K4me2/3...
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Review article epithelial to mesenchymal transition‑associated microRNAs in breast cancer
Despite major advances, breast cancer (BC) is the most commonly diagnosed carcinoma and remains a deadly disease among women worldwide. Many...
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Long noncoding RNA DLEU2 and ROR1 pathway induces epithelial-to-mesenchymal transition and cancer stem cells in breast cancer
Breast cancer (BC) patient who receives chemotherapy for an extended length of time may experience profound repercussions in terms of metastases and...
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Transcription factor Dp-1 knockdown downregulates thymidine kinase 1 expression to protect against proliferation and epithelial-mesenchymal transition in cervical cancer
Thymidine kinase 1 (TK1) level is an independent survival prognostic factor for both premalignant and malignant cervical pathologies. Herein, this...
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Arginase-1 promotes lens epithelial-to-mesenchymal transition in different models of anterior subcapsular cataract
BackgroundArginase-1 (ARG1) promotes collagen synthesis and cell proliferation. ARG1 is highly expressed in various tumour cells. The mechanisms of...
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A complex epigenome-splicing crosstalk governs epithelial-to-mesenchymal transition in metastasis and brain development
Epithelial-to-mesenchymal transition (EMT) renders epithelial cells migratory properties. While epigenetic and splicing changes have been implicated...
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LncRNA-MIAT activates hepatic stellate cells via regulating Hippo pathway and epithelial-to-mesenchymal transition
Long non-coding RNA-myocardial infarction-associated transcript (lncRNA-MIAT) has been reported to play an important role in the development of...
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Hypoxia and Epithelial-to-Mesenchymal Transition (EMT) in Cancer: A Non-coding RNA Perspective
A recent focus on the regulatory roles of non-coding RNAs has widened our knowledge of their biological functions. These regulatory roles inherently...
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Epithelial-mesenchymal transition-related signaling pathways in gastric Cancer cells distinctively respond to long-term experimental ketosis
BackgroundThe interrelationship between cellular metabolism and the epithelial-to-mesenchymal transition (EMT) process has made it an interesting...
