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Enzymatic biotransformation of Rb3 from the leaves of Panax notoginseng to ginsenoside rd by a recombinant β-xylosidase from Thermoascus aurantiacus
Given the important pharmacological activity of ginsenoside Rd but its low content in plants, the production of Rd by enzymatic transformation is of...
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A Bi-enzymatic Immobilized Nanobiocatalyst for the Biotransformation of Oleuropein to Hydroxytyrosol
Multi-enzymatic assemblies offer the opportunity of bringing in proximity several enzymes that are enabled to work together for the catalysis of... -
Biotransformation of progesterone by endophytic fungal cells immobilized on electrospun nanofibrous membrane
Biotransformation of steroids by fungi has been raised as a successful, eco-friendly, and cost-effective biotechnological alternative for chemical...
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Enzymatic Reactions in Unusual Reaction Media
The performance of enzymatic reactions in unusual reaction media offers a wide range of possibilities. Polar and nonpolar organic solvents,... -
Biotransformation approach to produce rare ginsenosides F1, compound Mc1, and Rd2 from major ginsenosides
The stems and leaves of Panax notoginseng contain high saponins, but they are often discarded as agricultural waste. In this study, the predominant...
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3α-Hydroxybufadienolides in Bufo gallbladders: structural insights and biotransformation
Bufadienolides, naturally occurring steroids primarily found in toads, have garnered attention for their pharmacological properties and ecological...
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Microbial biochemical pathways of arsenic biotransformation and their application for bioremediation
Arsenic is a ubiquitous toxic metalloid, the concentration of which is beyond WHO safe drinking water standards in many areas of the world, owing to...
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Interaction of Fungal Strains, Biomass, and pH to Produce Lignocellulosic Enzymes in Solid-State Fermentation for Sustainable Biotransformation of Sugarcane and Agave Bagasse
The mechanism underlying the production of fungal lignocellulolytic enzymes from lignocellulosic biomass remains unclear; therefore, it is imperative...
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Insights into fermentation with lactic acid bacteria on the flavonoids biotransformation of alfalfa silage
BackgroundOxidative stress is currently one of the main threats to animal health, and flavonoids in forage have good antioxidant activity. However,...
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Fruits of their labour: biotransformation reactions of yeasts during brewery fermentation
AbstractThere is a growing appreciation for the role that yeast play in biotransformation of flavour compounds during beverage fermentations. This is...
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Value Addition to Chemical Compounds Through Biotransformation
In the last few decades, the production of value-added chemical compounds through biocatalysis using microbes or their enzymes is offering the... -
Biotransformation of Industrially Important Steroid Drug Precursors
Steroids are known to act as wonder drugs. The production of steroidal hormones and drugs rests mainly on sterols of plant origin, but most of them... -
Effects of perfluoroalkyl substances (PFASs) and benzo[a]pyrene (BaP) co-exposure on phase I biotransformation in rainbow trout (Oncorhynchus mykiss)
The presence of perfluoroalkyl substances (PFASs) in the environment, especially in aquatic ecosystems, continues to be a significant concern for...
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Semisynthesis of Bis-Indole Alkaloid (−)-Melodinine K Enabled by a Combination of Biotransformation and Chemical Synthesis
Enzymatic biotransformation has become a widely used technique in synthetic chemistry to achieve difficult chemical transformations. Cytochrome P450... -
Enzymatic upcycling of wild-simulated ginseng leaves for enhancing biological activities and compound K
Compound K (CK), a ginsenoside with high bioavailability, is present at low levels in wild-simulated ginseng leaves (WSGL). WSGL contains the CK...
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Emerging Technique of Enzymatic Biotransformation of Amides to Hydroxamic Acid for Pharmaceutical and Dye Waste Treatment
The potential applications of acyltransferases in the synthesis of pharmaceutically significant hydroxamic acids have rendered it substantial... -
New derivatives of the iridoid specioside from fungal biotransformation
AbstractIridoids are widely found from species of Bignoniaceae family and exhibit several biological activities, such as anti-inflammatory,...
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Research progress and application of enzymatic synthesis of glycosyl compounds
AbstractGlucoside compounds are widely found in nature and have garnered significant attention in the medical, cosmetics, and food industries due to...
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Overexpression of chaperones GroEL/ES from Escherichia coli enhances indigo biotransformation production of cytochrome P450 BM3 mutant
The self-sufficient cytochrome P450 BM3 mutant (A74G/F87V/D168H/L188Q) can serve as a biocatalyst for whole-cell catalysis process of indigo....
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An enzymatic tandem reaction to produce odor-active fatty aldehydes
AbstractAldehydes represent a versatile and favored class of flavoring substances. A biocatalytic access to odor-active aldehydes was developed by...