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Revisiting the pericarp as a barrier restricting water entry/loss from cotyledons and embryonic axis of temperate desiccation-sensitive Quercus acorns
Main conclusionsFully mature acorns of Quercus variabilis , Q. aliena , Q. mongolica , and Q. glandulifera are desiccation-sensitive. X-ray computer...
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Nox4-IGF2 Axis Promotes Differentiation of Embryoid Body Cells Into Derivatives of the Three Embryonic Germ Layers
Reactive oxygen species (ROS) play important roles as second messengers in a wide array of cellular processes including differentiation of stem...
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Identification of the central intermediate in the extra-embryonic to embryonic endoderm transition through single-cell transcriptomics
High-resolution maps of embryonic development suggest that acquisition of cell identity is not limited to canonical germ layers but proceeds via...
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Embryonic organizer formation disorder leads to multiorgan dysplasia in Down syndrome
Despite the high prevalence of Down syndrome (DS) and early identification of the cause (trisomy 21), its molecular pathogenesis has been poorly...
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Manipulation of Embryonic Cleavage Geometry Using Magnetic Tweezers
The geometry of reductive divisions that mark the development of early embryos instructs cell fates, sizes, and positions, by mechanisms that remain...
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Beyond energy provider: multifunction of lipid droplets in embryonic development
Since the discovery, lipid droplets (LDs) have been recognized to be sites of cellular energy reserves, providing energy when necessary to sustain...
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Thyroid axis participates in high-temperature-induced male sex reversal through its activation by the stress response
Environmental changes alter the sex fate in about 15% of vertebrate orders, mainly in ectotherms such as fish and reptiles. However, the effects of...
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CD32 captures committed haemogenic endothelial cells during human embryonic development
During embryonic development, blood cells emerge from specialized endothelial cells, named haemogenic endothelial cells (HECs). As HECs are rare and...
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The histone chaperone function of Daxx is dispensable for embryonic development
Daxx functions as a histone chaperone for the histone H3 variant, H3.3, and is essential for embryonic development. Daxx interacts with Atrx to form...
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Embryonic thermal manipulation: a potential strategy to mitigate heat stress in broiler chickens for sustainable poultry production
Due to high environmental temperatures and climate change, heat stress is a severe concern for poultry health and production, increasing the...
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Exosomal miR-17-5p from human embryonic stem cells prevents pulmonary fibrosis by targeting thrombospondin-2
BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and irreversible lung disease characterized by pulmonary fibrosis and lung...
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DNA methylation restricts coordinated germline and neural fates in embryonic stem cell differentiation
As embryonic stem cells (ESCs) transition from naive to primed pluripotency during early mammalian development, they acquire high DNA methylation...
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Assembly of complete mouse embryo models from embryonic and induced stem cell types in vitro
The interaction between embryonic and extraembryonic tissues is critical in natural mouse embryogenesis. Here, to enable such interaction in vitro,...
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A Modified Murine Embryonic Stem Cell Test for Evaluating the Teratogenic Effects of Drugs
Animal-based test systems have traditionally been used to screen for the potential teratogenic activity of drugs. Still, their deficits in predicting...
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Developmental progression continues during embryonic diapause in the roe deer
Embryonic diapause in mammals is a temporary developmental delay occurring at the blastocyst stage. In contrast to other diapausing species...
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Embryonic exposure to decitabine induces multiple neural tube defects in develo** zebrafish
Neural tube defects are severe congenital disorders of the central nervous system that originate during embryonic development when the neural tube...
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Temperature-induced embryonic diapause in chickens is mediated by PKC-NF-κB-IRF1 signaling
BackgroundEmbryonic diapause (dormancy) is a state of temporary arrest of embryonic development that is triggered by unfavorable conditions and...
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Embryonic and larval development of a highly threatened killifish: ecological and conservation implications
Anthropogenic habitat degradation and alien invasive species have led to the rapid decline of freshwater fish biodiversity globally. The knowledge of...
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Highly conserved and extremely evolvable: BMP signalling in secondary axis patterning of Cnidaria and Bilateria
Bilateria encompass the vast majority of the animal phyla. As the name states, they are bilaterally symmetric, that is with a morphologically clear...
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Exploring the phytohormonal crosstalk during embryonic journey and germination process of Vateria indica L. seeds utilizing LCMS/MS technology
Vateria indica L. is an endangered tree species indigenous to South Western-Ghats regions of India, which is of immense economic importance. The...
