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Continuous Bioprocessing for Downstream
Continuous biomanufacturing is increasingly considered as a way to intensify production of biopharmaceuticals and to reduce manufacturing costs by... -
Transcription Needs Translation Initiation of the Downstream Gene to Continue Downstream at Intercistronic Junctions in E. Coli
We have reported a gal mutant called galE stop 0 , wherein the galE stop codon was changed to a sense codon. The experiment results demonstrated that...
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Downstream passage performance of silver eel at an angled rack: effects of behavior and morphology
The European eel is critically endangered due to heavy impact of anthropogenic factors, such as habitat fragmentation, overexploitation and climate...
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TISSUE: uncertainty-calibrated prediction of single-cell spatial transcriptomics improves downstream analyses
Whole-transcriptome spatial profiling of genes at single-cell resolution remains a challenge. To address this limitation, spatial gene expression...
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What are the common downstream molecular events between alcoholic and nonalcoholic fatty liver?
Liver fat storage, also called hepatic steatosis, is increasingly common and represents a very frequent diagnosis in the medical field. Excess fat is...
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Fibroblast Growth Factor 23 Bone Regulation and Downstream Hormonal Activity
Mineral homeostasis of calcium and phosphate levels is one critical component to the maintenance of bone mineral density (BMD) and strength. Diseases...
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River Sediments Downstream of Villages in a Karstic Watershed Exhibited Increased Numbers and Higher Diversity of Nontuberculous Mycobacteria
The impact of residential villages on the nontuberculous mycobacteria (NTM) in streams flowing through them has not been studied in detail. Water and...
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Daily and Seasonal Variation in Downstream Migration of Juvenile Pink Salmon Oncorhynchus gorbuscha (Salmonidae) in Rivers across the Sakhalin and Kuril Region
AbstractThe four-year study outcomes for downstream migration of the juvenile Pink salmon Oncorhynchus gorbuscha in the Bolshaya Khuzi, Malaya...
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GATA3 functions downstream of BRCA1 to promote DNA damage repair and suppress dedifferentiation in breast cancer
BackgroundInadequate DNA damage repair promotes aberrant differentiation of mammary epithelial cells. Mammary luminal cell fate is mainly determined...
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ACE2 inhibits proliferation of smooth muscle cell through AT1R and its downstream signaling pathway
To investigate the effect of the angiotensin converting enzyme 2 (ACE2) on AT1R expression, ERK1/2 and STAT3 protein phosphorylation in rat vascular...
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Low water temperature and increased discharge trigger downstream spawning migration of ayu Plecoglossus altivelis
This study examined the combined effects of water temperature and discharge on the downstream spawning migration of ayu Plecoglossus altivelis , with...
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Collaborative Governance for Reviving Tiber Landscapes Downstream of Rome
The regeneration of river landscapes in urban and peri-urban areas is increasingly relevant on local agendas to promote integrated policies framing... -
Bisphenol S causes excessive estrogen synthesis by activating FSHR and the downstream cAMP/PKA signaling pathway
Estrogen excess in females has been linked to a diverse array of chronic and acute diseases. Emerging research shows that exposure to estrogen-like...
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Efficient Microfluidic Downstream Processes for Rapid Antibody Hit Confirmation
Microfluidics has been recently applied to better understand the spatial and temporal progression of the immune response in several species, for tool... -
Hydrologic Connectivity and Flow Generation from California Vernal Pool, Swale, and Headwater Stream Complexes to Downstream Waters
Many headwater wetlands are integrated into flowpath networks and can serve as sources of streamflow for downgradient waters. We demonstrate this...
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Experiment-based computational model predicts that IL-6 classic and trans-signaling exhibit similar potency in inducing downstream signaling in endothelial cells
Inflammatory cytokine mediated responses are important in the development of many diseases that are associated with angiogenesis. Targeting...
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Automated workflows using Quantitative Colour Pattern Analysis (QCPA): a guide to batch processing and downstream data analysis
Animal and plant colouration presents a striking dimension of phenotypic variation, the study of which has driven general advances in ecology,...
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Environmental Impacts Related to Upstream and Downstream Processing of Haematococcus pluvialis
One of the most promising sources of astaxanthin is the microalgae Haematococcus pluvialis. Biotechnological methods of natural production of... -
Statistical Designs to Improve Downstream Processing
The efficient extraction and purificationPurification of recombinant proteins from leaf and seed Seeds tissues is often a challenging task,... -
MethylC-analyzer: a comprehensive downstream pipeline for the analysis of genome-wide DNA methylation
DNA methylation is a crucial epigenetic modification involved in multiple biological processes and diseases. Current approaches for measuring...