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Dose-specific efficacy of adipose-derived mesenchymal stem cells in septic mice
BackgroundMesenchymal stem cells (MSCs) therapy for sepsis has been extensively studied in the past decade; however, the treatment regimen and...
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Accurate models and nutritional strategies for specific oxidative stress factors: Does the dose matter in swine production?
Oxidative stress has been associated with a number of physiological problems in swine, including reduced production efficiency. Recently, although...
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Sex-Specific and Dose-Dependent Effects of Drag-Reducing Polymers on Microcirculation and Tissue Oxygenation in Rats After Traumatic Brain Injury
Traumatic brain injury (TBI) ultimately leads to a reduction in the cerebral metabolic rate for oxygen due to ischemia. Previously, we showed that... -
Protective effect of Achyranthes aspera against compound 48/80, histamine and ovalbumin-induced allergic disorders in murine model
BackgroundAchyranthes aspera L. (family Amaranthaceae) is a plant species valued in Ayurveda for the treatment of respiratory ailments. Scientific...
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Morphological Abnormalities
Abnormal plant growth is an immediate effect after treatment of plant parts with either physical or chemical mutagens. Mutagen effect can result in... -
Glucocorticoid Effect in Cancer Patients
The use of glucocorticoids is very varied in the context of cancer patients and includes the treatment of symptoms related to cancer, but also the... -
Synergistic Effect of Maternal Micronutrient Supplementation on ORFV DNA Vaccine Immune Response in a Pregnant Model
Contagious ecthyma is a contagious zoonotic disease caused by the Orf virus that can infect farm animals and humans, but no vaccine is available for...
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Effect of Hydrogen Sulphide on Spontaneous Contractions of the Rat Jejunum: Role of KV, KCa, and Kir Channels
AbstractIn this study we investigated the role of voltage dependent (K V ), Ca 2+ -activated (K Ca ), and inward rectifier (K ir ) potassium channels in the...
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Effect of GLITEROS specific-diabetes enteral formula modification based on tempe flour, jicama flour and sunflower seed flour on score pancreatic damage, number and diameter of the islets of langerhans of hyperglycemic rats pancreatic cells with streptozotocin induction
Tempeh, yam, and sunflower's flour have been known to have antidiabetic effects, but their combined effect on the histopathology of hyperglycemic rat...
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Antimicrobial Susceptibility of Staphylococcus aureus Strains and Effect of Phloretin on Biofilm Formation
Staphylococcus aureus and methicillin-resistant S. aureus (MRSA) are known to be responsible of various infections, including biofilm-associated...
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A Critical Analysis of Possible Mechanisms for the Oxygen Effect in Radiation Therapy with FLASH
The aim of this review is to stimulate readers to undertake appropriate investigations of the mechanism for a possible oxygen effect in FLASH. FLASH... -
Effect of Fluoride on the Expression of 8-Hydroxy-2′-Deoxyguanosine in the Blood, Kidney, Liver, and Brain of Rats
Excessive exposure of fluoride not only leads to damage on bone, but also has an adverse effect on soft tissues. Oxidative DNA damage induced by...
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Effect of Methyl Jasmonate and Salicylic Acid on the Enrichment of Carbazole Alkaloids in Murraya koenigii (L.) Spreng
Elicitors have a substantial impact on the accumulation of phytochemical components in wild plants. The present study aimed to evaluate the impact of...
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Pharmacoencephalographic Assessment of Antiphyschotic Agents’ Effect Dose-Dependency in Rats
AbstractPharmacoencephalography (pharmaco-EEG) is a prominent instrument for the pharmacological screening of new psychoactive molecules. This...
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Potential Effect of Nigella sativa on Osteoporosis in Ovariectomized Rats: Possible Role of Hypoxia Inducible Factor 1-α
AbstractThe decline in estrogen in postmenopausal women allows accumulation of hypoxia inducible factor 1-α (HIF1-α) in osteoclasts, resulting in...
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The sphingosine-1-phosphate receptor 1 mediates the atheroprotective effect of eicosapentaenoic acid
Omega-3 polyunsaturated fatty acids (ω-3 PUFAs) have been associated with potential cardiovascular benefits, partly attributed to their bioactive...
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Effect of Non-Specific Porins from the Outer Membrane of Yersinia pseudotuberculosis on Mice Brain Cortex Tissues
AbstractIt was found that a single-dose immunization of mice with Yersinia pseudotuberculosis porins OmpF and OmpC causes development of...
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Median Tissue Culture Infectious Dose 50 (TCID50) Assay to Determine Infectivity of Cytopathic Viruses
The emergence of zoonotic viruses like severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus... -
The Effect of 20-Hydroxyecdysone on the Functioning of Isolated Mouse Skeletal Muscle Mitochondria
Abstract —In this work we have studied the effect of the phytoecdysteroid 20-hydroxyecdysone (20E) on the functioning of mouse skeletal muscle...
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Effect of Neurohypophysial Hormones on Protein Excretion by the Kidneys
AbstractVasopressin (VP) is one of the main factors affecting intraglomerular hemodynamics, filtration pressure, and the state of mesangial...