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Kynurenine pathway as alternative biosynthetic pathway for fusaric acid in Fusarium oxysporum f.sp. cubense
Banana fusarium wilt caused by Fusarium. oxysporum f.sp. cubense race 4, has already become one of the main diseases in banana production. Previous...
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Recent advances in biocatalytic derivatization of l-tyrosine
l -Tyrosine is an aromatic, polar, non-essential amino acid that contains a highly reactive α-amino, α-carboxyl, and phenolic hydroxyl group....
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Toward Understanding the Role of Chromatin in Secondary Metabolite Gene Regulation in the Rice Pathogen Fusarium fujikuroi
Fusarium fujikuroi (teleomorph Gibberella fujikuroi) is a notorious rice pathogen and the causative agent of the bakanae (foolish seedling) disease....
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Silencing of a second dimethylallyltryptophan synthase of Penicillium roqueforti reveals a novel clavine alkaloid gene cluster
Penicillium roqueforti produces several prenylated indole alkaloids, including roquefortine C and clavine alkaloids. The first step in the...
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Diversity of Seed Endophytes: Causes and Implications
The immense importance of microbial symbioses with plants, animals, and other eukaryotes is meeting with ever increasing awareness and interest....
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After Air, Light, and Water, the Next Most Important Thing Is Grass: An Introduction to the Epichloë–Grass Symbiosis
Epichloë (Clavicipitaceae) is a genus of filamentous fungal endophytes that have co-evolved with cool-season grasses with which they form perpetual,...
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Branching and converging pathways in fungal natural product biosynthesis
In nature, organic molecules with great structural diversity and complexity are synthesized by utilizing a relatively small number of starting...
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Adaptations of Pseudoxylaria towards a comb-associated lifestyle in fungus-farming termite colonies
Characterizing ancient clades of fungal symbionts is necessary for understanding the evolutionary process underlying symbiosis development. In this...
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Synthetic biology, combinatorial biosynthesis, and chemo‑enzymatic synthesis of isoprenoids
Isoprenoids are a large class of natural products with myriad applications as bioactive and commercial compounds. Their diverse structures are...
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Molecular mechanisms in grass-Epichloë interactions: towards endophyte driven farming to improve plant fitness and immunity
All plants harbor many microbial species including bacteria and fungi in their tissues. The interactions between the plant and these microbes could...
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Reinvestigation of the substrate specificity of a reverse prenyltransferase NotF from Aspergillus sp. MF297-2
NotF from Aspergillus sp. MF297-2 and BrePT from Aspergillus versicolor catalyze a reverse C2-prenylation of brevianamide F in the biosynthetic...
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Genus level analysis of PKS-NRPS and NRPS-PKS hybrids reveals their origin in Aspergilli
BackgroundFilamentous fungi produce a vast amount of bioactive secondary metabolites (SMs) synthesized by e.g. hybrid polyketide...
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Fungal Genes Encoding Enzymes Used in Cheese Production and Fermentation Industries
The extensive usage of milk and milk products worldwide has attracted special attention to cheese because of its health benefits and easy scale-up....
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Understanding the secondary metabolite production of Gibberella fujikuroi species complex in genomic era
The Gibberella fujikuroi complex (GFC), consists of more than 50 anamorphs and 11 sexually fertile biological species (mating populations MP-A to...
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Genomes and secretomes of Ascomycota fungi reveal diverse functions in plant biomass decomposition and pathogenesis
BackgroundThe dominant fungi in arid grasslands and shrublands are members of the Ascomycota phylum. Ascomycota fungi are important drivers in carbon...
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Large-scale transcriptomics to dissect 2 years of the life of a fungal phytopathogen interacting with its host plant
BackgroundThe fungus Leptosphaeria maculans has an exceptionally long and complex relationship with its host plant, Brassica napus , during which it...
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Secondary metabolism in Fusarium fujikuroi: strategies to unravel the function of biosynthetic pathways
The fungus Fusarium fujikuroi causes bakanae disease of rice due to its ability to produce the plant hormones, the gibberellins. The fungus is also...
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Mutation on Gly115 and Tyr205 of the cyclic dipeptide C2-prenyltransferase FtmPT1 increases its catalytic activity toward hydroxynaphthalenes
The fungal cyclic dipeptide prenyltransferase FtmPT1 from Aspergillus fumigatus catalyzes a regular C2 -prenylation of brevianamide F ( cyclo - l -Trp- l -Pr...
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The current status on secondary metabolites produced by plant pathogenic Colletotrichum species
The fungal genus Colletotrichum contains about 190 species, many of which are responsible for serious plant diseases including those of commercial...
