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1. Nuclear organization and regulation of the differentiated state

   Regulation of the differentiated identity requires active and continued supervision. Inability to maintain the differentiated state is a hallmark of...

   Eliya Bitman-Lotan, Amir Orian in Cellular and Molecular Life Sciences

   Article Open access 28 January 2021
   

2. Quercetin declines LPS induced inflammation and augments adiponectin expression in 3T3-L1 differentiated adipocytes SIRT-1 dependently

   Background

   Inflammation is an important factor contributing to obesity-induced metabolic disorders. Different investigations confirm that local...

   Zahra Noori, Mohammad Sharifi, ... Sayed Mohammad Shafiee in Molecular Biology Reports

   Article 23 March 2024
   

3. Adding pieces to the puzzle of differentiated-to-anaplastic thyroid cancer evolution: the oncogene E2F7

   Anaplastic Thyroid Cancer (ATC) is the most aggressive and de-differentiated subtype of thyroid cancer. Many studies hypothesized that ATC derives...

   Mila Gugnoni, Eugenia Lorenzini, ... Gloria Manzotti in Cell Death & Disease

   Article Open access 10 February 2023
   

4. Differentiated Epithelial Cells of the Gut

   The intestine is a prime example of self-renewal where stem cells give rise to progenitor cells called transit-amplifying cells which differentiate...

   Andrea Bonilla-Díaz, Paloma Ordóñez-Morán in Intestinal Differentiated Cells

   Protocol 2023
   

5. CRISPRi gene modulation and all-optical electrophysiology in post-differentiated human iPSC-cardiomyocytes

   Uncovering gene-phenotype relationships can be enabled by precise gene modulation in human induced pluripotent stem-cell-derived cardiomyocytes...

   Julie L. Han, Yuli W. Heinson, ... Emilia Entcheva in Communications Biology

   Article Open access 07 December 2023
   

6. Differentiated Approach to Pharmacotherapy of Autism Spectrum Disorders: Biochemical Aspects

   Abstract

   Autism Spectrum Disorders (ASD) are highly heterogeneous neurodevelopmental disorders caused by a complex interaction of numerous genetic and...

   Irina S. Boksha, Tatyana A. Prokhorova, ... Gulnur Sh. Burbaeva in Biochemistry (Moscow)

   Article 20 March 2023

7. Comparison of POU5F1 gene expression and protein localization in two differentiated and undifferentiated spermatogonial stem cells

   The POU domain, class 5, transcription factor 1 (POU5F1), plays a vital role in creating pluripotency and maintaining self-renewal of the...

   Mahla Masoudi, Hossein Azizi, ... Dariush Gholami in Biologia Futura

   Article 30 December 2022
   

8. Expression Profile of Isogenic Early Mesodermal Cells Differentiated from Human Induced Pluripotent Stem Cells

   Abstract

   Scar formation during normal regeneration of damaged tissue can lead to noticeable cosmetic and functional defects of organs and thus...

   A. V. Selezneva, E. V. Korobko, ... Yu. G. Suzdaltseva in Journal of Evolutionary Biochemistry and Physiology

   Article 01 March 2024
   

9. Differentiated genomic footprints suggest isolation and long-distance migration of Hmong-Mien populations

   Background

   The underrepresentation of Hmong-Mien (HM) people in Asian genomic studies has hindered our comprehensive understanding of the full...

   Guanglin He, Peixin Wang, ... Mengge Wang in BMC Biology

   Article Open access 25 January 2024
   

10. Dysregulation of Immune Tolerance to Autologous iPSCs and Their Differentiated Derivatives

    Abstract

    Induced pluripotent stem cells (iPSCs), capable of differentiating into any cell type, are a promising tool for solving the problem of donor...

    Margarita E. Bogomiakova, Alexandra N. Bogomazova, Maria A. Lagarkova in Biochemistry (Moscow)

    Article 31 May 2024
    

11. LGR5 Modulates Differentiated Phenotypes of Chondrocytes Through PI3K/AKT Signaling Pathway

    Background:

    Tissue engineering is increasingly viewed as a promising avenue for functional cartilage reconstruction. However, chondrocyte...

    Xu Wu, Yaoyao Fu, ... Tianyu Zhang in Tissue Engineering and Regenerative Medicine

    Article 21 May 2024
    

12. Characteristics of nuclear architectural abnormalities of myotubes differentiated from Lmna^H222P/H222P skeletal muscle cells

    The presence of nuclear architectural abnormalities is a hallmark of the nuclear envelopathies, which are a group of diseases caused by mutations in...

    Eiji Wada, Nao Susumu, ... Yukiko K. Hayashi in In Vitro Cellular & Developmental Biology - Animal

    Article 09 May 2024
    

13. Self-Regulation in Competitive Sports

    The chapter provides an overview of self-regulation in competitive sports. Self-regulation refers to conscious as well as unconscious processes that...

    Jürgen Beckmann, Denise Beckmann-Waldenmayer, Svenja Anna Wolf in Sport and Exercise Psychology

    Chapter 2023
    

14. Nitrosylation of β2-Tubulin Promotes Microtubule Disassembly and Differentiated Cardiomyocyte Beating in Ischemic Mice

    Background:

    Beating cardiomyocyte regeneration therapies have revealed as alternative therapeutics for heart transplantation. Nonetheless, the...

    Da Hyeon Choi, Seong Ki Kang, ... Sang Ick Park in Tissue Engineering and Regenerative Medicine

    Article 07 September 2023
    

15. Epigenetic Regulation in Almond

    Rapid advances in sequencing technologies have enabled researchers to reconceptualize genomes as dynamic entities with functions beyond storage and...

    Jonathan Fresnedo Ramírez, Katherine D’Amico-Willman, Thomas M. Gradziel in The Almond Tree Genome

    Chapter 2023
    

16. Post-transcriptional regulation of myogenic transcription factors during muscle development and pathogenesis

    The transcriptional regulation of skeletal muscle (SKM) development (myogenesis) has been documented for over 3 decades and served as a paradigm for...

    Shen-Liang Chen, Chuan-Che Wu, ... Tzu-Han Weng in Journal of Muscle Research and Cell Motility

    Article 11 January 2024
    

17. CHCHD2 up-regulation in Huntington disease mediates a compensatory protective response against oxidative stress

    Huntington disease (HD) is a neurodegenerative disease caused by the abnormal expansion of a polyglutamine tract resulting from a mutation in the HTT ...

    Xuanzhuo Liu, Fang Wang, ... **aohong Xu in Cell Death & Disease

    Article Open access 10 February 2024
    

18. RNA-Mediated Regulation of Glycolysis in Embryonic Stem Cell Pluripotency and Differentiation

    Purpose of Review

    The maintenance and differentiation of embryonic stem cells are strictly coordinated with their metabolic status. As a core part of...

    Wei Fan, **aoling Li in Current Stem Cell Reports

    Article Open access 09 May 2024
    

19. Ubiquitin-Proteasome System in the Regulation of Cell Pluripotency and Differentiation

    Abstract

    Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) demonstrate unique abilities for continuous self-renewal and...

    U. I. Podenkova, I. V. Zubarev, ... A. S. Tsimokha in Cell and Tissue Biology

    Article 22 September 2023
    

20. Bradykinin promotes immune responses in differentiated embryonic neurospheres carrying APP^swe and PS1^dE9 mutations

    Background

    Neural progenitor cells (NPCs) can be cultivated from develo** brains, reproducing many of the processes that occur during neural...

    Guilherme Juvenal, Carine Meinerz, ... Henning Ulrich in Cell & Bioscience

    Article Open access 18 June 2024