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Toll-like receptor 3 signaling drives enteric glial cells against dextran sulfate sodium-induced colitis in mice
The activation of toll-like receptor 3 (TLR3) has been reported to attenuate astrocytes injury in central nervous system, but its effect on enteric...
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Lactobacillus rhamnosus KBL2290 Ameliorates Gut Inflammation in a Mouse Model of Dextran Sulfate Sodium-Induced Colitis
Ulcerative colitis, a major form of inflammatory bowel disease (IBD) associated with chronic colonic inflammation, may be induced via overreactive...
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Effect of 3,3′-diselenodipropionic Acid on Dextran Sodium Sulfate–Induced Ulcerative Colitis in Mice
3,3′-Diselenodipropionic acid (DSePA), a synthetic organoselenium compound, has received considerable attention because of its antioxidant properties...
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5-Aminosalicylic acid ameliorates dextran sulfate sodium-induced colitis in mice by modulating gut microbiota and bile acid metabolism
Colitis develops via the convergence of environmental, microbial, immunological, and genetic factors. The medicine 5-aminosalicylic acid (5-ASA) is...
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Novel Phocaeicola Strain Ameliorates Dextran Sulfate Sodium-induced Colitis in Mice
Previously, we isolated a novel Phocaeicola strain, Phocaeicola faecalis FXJYN30E22, from the feces of a healthy human from China. Metagenomic...
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Lacticaseibacillus paracasei CCFM1222 Ameliorated the Intestinal Barrier and Regulated Gut Microbiota in Mice with Dextran Sulfate Sodium-Induced Colitis
Lacticaseibacillus paracasei has been regarded as a probiotic bacterium because of its role in anti-inflammatory properties and maintenance of...
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Morphology of Rat Muscle Tissue after Implantation of Delivery Systems Consisting of Porous CaCO3 Vaterites Doped with Dextran Sulfate and Containing Doxorubicin
AbstractBehavior of drug delivery systems based on porous СаСО 3 vaterites doped with dextran sulfate is described. The drug delivery systems...
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Selection strategy of dextran sulfate sodium-induced acute or chronic colitis mouse models based on gut microbial profile
BackgroundDextran sulfate sodium (DSS) replicates ulcerative colitis (UC)-like colitis in murine models. However, the microbial characteristics of...
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Nattokinase enhances the preventive effects of Escherichia coli Nissle 1917 on dextran sulfate sodium-induced colitis in mice
Nattokinase with excellent anti-thrombotic, anti-inflammatory, anti-tumor, and anti-hypertension properties has been used in the development of...
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Potential role of Lactobacillus plantarum in colitis induced by dextran sulfate sodium through altering gut microbiota and host metabolism in murine model
Inflammatory bowel disease (IBD) is a chronic lifelong disease characterized by inflammation of the gastrointestinal tract. Although more and more...
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Inflammatory responses of C57BL/6NKorl mice to dextran sulfate sodium-induced colitis: comparison between three C57BL/6 N sub-strains
BackgroundInflammatory bowel disease (IBD), including both Crohn’s disease and ulcerative colitis, are chronic human diseases that are challenging to...
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Oxidative stress exacerbates dextran sulfate sodium-induced ulcerative colitis in ICR mice
Ulcerative colitis (UC) is a complex, multifactorial disorder which can be aggravated by oxidative stress. Dextran sulfate sodium (DSS)-induced UC in...
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Histochemical Analysis of Heparan Sulfate 3-O-sulfotransferase Expression in Mouse Brain
In situ hybridization provides information for understanding the localization of gene expression in various tissues. The relative expression levels...
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Effect of Biopolymers and Functionalized by Them Vaterite Microparticles on Platelet Aggregation
AbstractVaterite microparticles, metastable form of calcium carbonate, are promising forms of delivery of medicinal compounds. For more efficient...
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Pretreatment with an antibiotics cocktail enhances the protective effect of probiotics by regulating SCFA metabolism and Th1/Th2/Th17 cell immune responses
BackgroundProbiotics are a potentially effective therapy for inflammatory bowel disease (IBD); IBD is linked to impaired gut microbiota and...
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Exosomes derived from EphB2-overexpressing bone marrow mesenchymal stem cells regulate immune balance and repair barrier function
BackgroundDisruption of intestinal barrier function and an imbalance in intestinal immunity are crucial for the occurrence and development of...
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Determination of Molecular Dimensions of Carbohydrate Polymers (Polysaccharides) by Size Exclusion Chromatography (SEC)
Calibrated size exclusion chromatography (SEC) is a useful tool for the analysis of molecular dimensions of polysaccharides. The calibration takes...
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Integrative analysis of single-cell RNA-seq and gut microbiome metabarcoding data elucidates macrophage dysfunction in mice with DSS-induced ulcerative colitis
Ulcerative colitis (UC) is a significant inflammatory bowel disease caused by an abnormal immune response to gut microbes. However, there are still...
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Homotherapy for heteropathy: therapeutic effect of Butein in NLRP3-driven diseases
BackgroundAberrant inflammatory responses drive the initiation and progression of various diseases, and hyperactivation of NLRP3 inflammasome is a...
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Loss of Mptx2 alters bacteria composition and intestinal homeostasis potentially by impairing autophagy
A recent single-cell survey of the small-intestinal epithelium suggests that mucosal pentraxin 2 ( Mptx2 ) is a new Paneth cell marker, but its...
