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CRISPR/Cas9 mediated editing of phytoene desaturase gene in squash
Gene editing using the Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated 9 (CRISPR/Cas9) system has become an important...
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Optimization of Virus-induced Phytoene Desaturase (PDS) gene silencing using Tobacco Rattle Virus in Coleus forskohlii
Virus-induced gene silencing (VIGS) is an effective reverse genetics method used to study the gene function by analysis of plants at phenotype and...
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Targeted gene knockout via CRISPR/Cas9: precise genome editing in eggplant (Solanum melongena) through phytoene desaturase gene disruption
Genome editing using CRISPR/Cas9 has become powerful tool for enabling targeted genetic changes into crop species. The present study was aimed to...
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Establishment of virus-induced gene silencing (VIGS) system in Luffa acutangula using Phytoene desaturase (PDS) and tendril synthesis related gene (TEN)
BackgroundVirus-induced gene silencing (VIGS) is a reverse genetics technology that can efficiently and rapidly identify plant gene functions....
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Effect of Mosaic Knockout of Phytoene Desaturase Gene NtPDS on Biosynthesis of Carotenoids in Nicotiana tabacum L.
AbstractCarotenoids are essential participants in photosynthesis and photo protection as well as growth, development, and stress response in plants....
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CRISPR/Cas9-mediated mutagenesis of phytoene desaturase in pigeonpea and groundnut
The CRISPR/Cas9 technology, renowned for its ability to induce precise genetic alterations in various crop species, has encountered challenges in its...
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A mutation in CsDWF7 gene encoding a delta7 sterol C-5(6) desaturase leads to the phenotype of super compact in cucumber (Cucumis sativus L.)
Key messageA novel super compact mutant, scp-3 , was identified using map-based cloning in cucumber. The CsDWF7 gene encoding a delta7 sterol C-5(6)...
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Membrane fatty acid desaturase: biosynthesis, mechanism, and architecture
AbstractFatty acid desaturase catalyzes the desaturation reactions by inserting double bonds into the fatty acyl chain, producing unsaturated fatty...
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A comparative analyses of lipid ratios representing desaturase enzyme activity between preterm and term infants within the first ten weeks of life
BackgroundDesaturase enzymes play a key role in several pathways including biosynthesis of poly- and mono- unsaturated fatty acids (PUFAs, MUFA). In...
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A mutant cotton fatty acid desaturase 2-1d allele causes protein mistargeting and altered seed oil composition
BackgroundCotton ( Gossypium sp.) has been cultivated for centuries for its spinnable fibers, but its seed oil also possesses untapped economic...
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Advances in regulation and function of stearoyl-CoA desaturase 1 in cancer, from bench to bed
Stearoyl-CoA desaturase 1 (SCD1) converts saturated fatty acids to monounsaturated fatty acids. The expression of SCD1 is increased in many cancers,...
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Genome-Wide Identification, Phylogenetic and Expression Pattern Analysis of Fatty Acid Desaturase Genes in Castor (Ricinus communis L.)
Fatty acid desaturase (FAD) plays a crucial role in plant growth, development, and stress response. The FADs have been identified and reported in...
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Identification and Functional Analysis of Acyl-Acyl Carrier Protein Δ9 Desaturase from Nannochloropsis oceanica
The oleaginous marine microalga Nannochloropsis oceanica strain IMET1 has attracted increasing attention as a promising photosynthetic cell factory...
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Deltex E3 ubiquitin ligase 4 promotes thyroid cancer progression through stearoyl-CoA desaturase 1
In this study, we aimed to explore the molecular role of Deltex E3 ubiquitin ligase 4 (DTX4) in thyroid cancer (TC) both in vitro and in vivo. The...
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The role of fatty acid desaturase 2 in multiple tumor types revealed by bulk and single-cell transcriptomes
BackgroundPrevious studies have demonstrated the important role of fatty acid desaturase 2 (FADS2) in governing tumorigenesis and tumor metastasis....
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Essential role of a conserved aspartate for the enzymatic activity of plasmanylethanolamine desaturase
Plasmalogens are an abundant class of glycerophospholipids in the mammalian body, with special occurrence in the brain and in immune cell membranes....
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Regulation of fatty acid desaturase- and immunity gene-expression by mbk-1/DYRK1A in Caenorhabditis elegans
BackgroundIn the nematode Caenorhabditis elegans , longevity in response to germline ablation, but not in response to reduced insulin/IGF1-like...
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Multiplexed gene editing in citrus by using a multi-intron containing Cas9 gene
Several expression systems have been developed in clustered regularly interspaced short palindromic repeats (CRISPR)-associated protein 9...
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A non-canonical Δ9-desaturase synthesizing palmitoleic acid identified in the thraustochytrid Aurantiochytrium sp. T66
AbstractThraustochytrids are oleaginous marine eukaryotic microbes currently used to produce the essential omega-3 fatty acid docosahexaenoic acid...
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Transcript expression level analysis of phytoene synthase and phytoene desaturase associated with β-carotene content in selected Kenyan Bitter melon
BackgroundBitter melon ( Momordica charantia L. ) is a widely cultivated food and medicinal plant native to the world's subtropics and tropics....
