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Effects of direct pulp cap** with recombinant human erythropoietin and/or mineral trioxide aggregate on inflamed rat dental pulp
ObjectiveThis study aimed to evaluate the dental pulp responses to recombinant human erythropoietin (rhEPO) and/or mineral trioxide aggregate (MTA)...
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Enhancing Vasculogenesis in Dental Pulp Development: DPSCs-ECs Communication via FN1-ITGA5 Signaling
BackgroundDental pulp regeneration therapy is a challenge to achieve early vascularization during treatment. Studying the regulatory mechanisms of...
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Dental Pulp Stem Cells in Endodontics: Advances, Applications, and Challenges
Stem cells are clonogenic cells capable of self-renewal and multi-lineage differentiation. Since the first isolation of dental pulp stem cells...
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Dental pulp and apical papilla cells senescence: causes, consequences, and prevention
Dental pulp under physiological conditions has a defense function, repair capacity, and important mechanisms in pathological processes. In addition,...
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Decellularized leaf-based biomaterial supports osteogenic differentiation of dental pulp mesenchymal stem cells
Decellularized tissues are an attractive scaffolds for 3D tissue engineering. Decellularized animal tissues have certain limitations such as the...
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Role of Hypoxia in Mesenchymal Stem Cells from Dental Pulp: Influence, Mechanism and Application
Mesenchymal stem cells (MSCs) from dental pulp (DP-MSCs), which include dental pulp stem cells (DPSCs) isolated from permanent teeth and stem cells...
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Pulp
Pulp is a connective tissue surrounded by a dental hard tissue, dentine, and is unique in that it does not permit volume change. Unlike enamel,...
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Dental Pulp Stem Cells in Endodontics: Advances, Applications, and Challenges
Stem cells are clonogenic cells capable of self-renewal and multi-lineage differentiation. Since the first isolation of dental pulp stem cells...
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Crucial Factors Influencing the Involvement of Odontogenic Exosomes in Dental Pulp Regeneration
Recent progress in exosome based studies has revealed that they possess several advantages over cells, including "cell-free" properties, low...
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Epithelium-derived SCUBE3 promotes polarized odontoblastic differentiation of dental mesenchymal stem cells and pulp regeneration
BackgroundSignal peptide-CUB-EGF domain-containing protein 3 (SCUBE3), a secreted multifunctional glycoprotein whose transcript expression is...
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Extracellular Vesicles Carrying RUNX3 Promote Differentiation of Dental Pulp Stem Cells
Background:This study aims to clarify the mechanism underlying dental pulp cells-extracellular vesicles (DPC–EVs) carrying runt-related transcription...
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Odontoblasts release exosomes to regulate the odontoblastic differentiation of dental pulp stem cells
BackgroundDental pulp stem cells (DPSCs) play a crucial role in dentin-pulp complex regeneration. Further understanding of the mechanism by which...
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Periapical bacterial disinfection is critical for dental pulp regenerative cell therapy in apical periodontitis in dogs
BackgroundApplication of pulp regenerative cell therapy for mature teeth with periapical lesions is a critical clinical challenge. The bacterial...
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Flow-dependent shear stress affects the biological properties of pericyte-like cells isolated from human dental pulp
BackgroundHuman dental pulp stem cells represent a mesenchymal stem cell niche localized in the perivascular area of dental pulp and are...
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Evaluating the efficacy of human dental pulp stem cells and scaffold combination for bone regeneration in animal models: a systematic review and meta-analysis
IntroductionHuman adult dental pulp stem cells (hDPSC) and stem cells from human exfoliated deciduous teeth (SHED) hold promise in bone regeneration...
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MiR-483-3p promotes dental pulp stem cells osteogenic differentiation via the MAPK signaling pathway by targeting ARRB2
Human dental pulp stem cells (DPSCs) have become an important component for bone tissue engineering and regenerative medicine due to their ability to...
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Intercellular crosstalk in adult dental pulp is mediated by heparin-binding growth factors Pleiotrophin and Midkine
BackgroundIn-depth knowledge of the cellular and molecular composition of dental pulp (DP) and the crosstalk between DP cells that drive tissue...
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TAS2R supports odontoblastic differentiation of human dental pulp stem cells in the inflammatory microenvironment
BackgroundInflammatory microenvironment promotes odontoblastic differentiation in human dental pulp stem cells (hDPSCs), but the regulatory...
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Preventive Effects of Dental Pulp Stem Cell-conditioned Media on Anti-RANKL Antibody-Related Osteonecrosis of the Jaw
Medication-related osteonecrosis of the jaw is a serious disease occurring in patients with cancer and osteoporosis, who are undergoing treatment...
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Osteogenic Differentiation Capacity of Dental Pulp Stem Cells on 3D Printed Polyurethane/Boric Acid Scaffold
Additive manufacturing is growing in the area of dentistry and orthopedics due to the potential for the fabrication of individual implants. In this...
