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Seed Development and Maturation
In plants, a fascinating set of post-fertilization events result in the development of a dispersal unit known as a seed. During the maturation phase,...
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Delayed access to feed early post-hatch affects the development and maturation of gastrointestinal tract microbiota in broiler chickens
BackgroundThe first two weeks of post-hatch (PH) growth in broilers (meat-type birds) are critical for gut development and microbiota colonization....
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Omentin-1 drives cardiomyocyte cell cycle arrest and metabolic maturation by interacting with BMP7
Mammalian cardiomyocytes (CMs) undergo maturation during postnatal heart development to meet the increased demands of growth. Here, we found that...
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Non-linear effects on the population performance of Bighead Carp under different maturation schedules
Bighead Carp currently threatens to invade the Laurentian Great Lakes from the Mississippi River, but the novel climatic conditions it will encounter...
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Delayed plumage signals social status in a mutually ornamented bird
The status signaling hypothesis suggests that inconspicuous plumages are an honest signal of subordination in social animals, including those...
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ISL1 controls pancreatic alpha cell fate and beta cell maturation
BackgroundGlucose homeostasis is dependent on functional pancreatic α and ß cells. The mechanisms underlying the generation and maturation of these...
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In-organoid single-cell CRISPR screening reveals determinants of hepatocyte differentiation and maturation
BackgroundHarnessing hepatocytes for basic research and regenerative medicine demands a complete understanding of the genetic determinants underlying...
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Cardiomyocyte Maturation–the Road is not Obstructed
Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) represent one of the most promising ways to treat cardiovascular diseases. High-purity...
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Sec22b regulates phagosome maturation by promoting ORP8-mediated lipid exchange at endoplasmic reticulum-phagosome contact sites
Phagosome maturation is critical for immune defense, defining whether ingested material is destroyed or converted into antigens. Sec22b regulates...
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Loss of Grin2a causes a transient delay in the electrophysiological maturation of hippocampal parvalbumin interneurons
N-methyl-D-aspartate receptors (NMDARs) are ligand-gated ionotropic glutamate receptors that mediate a calcium-permeable component to fast excitatory...
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Methylobacterium sp. isolated from the midgut of Anopheles stephensi inhibits egg maturation in host ovary
The gut bacteria of insects are associated with digestion, nutrition, and reproduction. The midgut bacteria of Anopheles mosquitoes have been...
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Synergistic effects of hormones on structural and functional maturation of cardiomyocytes and implications for heart regeneration
The limited endogenous regenerative capacity of the human heart renders cardiovascular diseases a major health threat, thus motivating intense...
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Distinct roles for SOX2 and SOX21 in differentiation, distribution and maturation of pulmonary neuroendocrine cells
Pulmonary neuroendocrine (NE) cells represent a small population in the airway epithelium, but despite this, hyperplasia of NE cells is associated...
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Overexpression of KCNJ2 enhances maturation of human-induced pluripotent stem cell-derived cardiomyocytes
BackgroundAlthough human-induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) are a promising cell resource for cardiovascular research,...
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Molecular mechanisms of miR172a and its target gene LbrTOE3 regulating maturation in Lilium
Main conclusionLbr -miR172a could promote the growth phase transition and shorten maturation in Lilium , while LbrTOE3 inhibited this process and...
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Structural and molecular determinants of Candida glabrata metacaspase maturation and activation by calcium
Metacaspases are caspase-like homologs which undergo a complex maturation process involving multiple intra-chain cleavages resulting in a composite...
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Hominoid SVA-lncRNA AK057321 targets human-specific SVA retrotransposons in SCN8A and CDK5RAP2 to initiate neuronal maturation
SINE-VNTR-Alu (SVA) retrotransposons arose and expanded in the genome of hominoid primates concurrent with the slowing of brain maturation. We report...
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Effects of temperature and photoperiod on the growth and maturation of parthenogenetic Petalonia binghamiae
The effects of temperature and photoperiod on the growth rate and maturation rate of the parthenogenetic strain of the brown alga Petalonia binghamiae ...
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YAP and TAZ play a crucial role in human erythrocyte maturation and enucleation
BackgroundYes-associated protein (YAP) and WW domain-containing transcription regulator protein 1 (WWTR1, also known as TAZ) are two key...
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Morphological diversification and functional maturation of human astrocytes in glia-enriched cortical organoid transplanted in mouse brain
Astrocytes, the most abundant glial cell type in the brain, are underrepresented in traditional cortical organoid models due to the delayed onset of...
