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  1. Assessing the reliability of point mutation as data augmentation for deep learning with genomic data

    Background

    Deep neural networks (DNNs) have the potential to revolutionize our understanding and treatment of genetic diseases. An inherent limitation...

    Hyunjung Lee, Utku Ozbulak, ... Joris Vankerschaver in BMC Bioinformatics
    Article Open access 30 April 2024
  2. Mdwgan-gp: data augmentation for gene expression data based on multiple discriminator WGAN-GP

    Background

    Although gene expression data play significant roles in biological and medical studies, their applications are hampered due to the...

    Rongyuan Li, **gli Wu, ... Qi Zhu in BMC Bioinformatics
    Article Open access 13 November 2023
  3. Prediction of blood–brain barrier penetrating peptides based on data augmentation with Augur

    Background

    The blood–brain barrier serves as a critical interface between the bloodstream and brain tissue, mainly composed of pericytes, neurons,...

    Zhi-Feng Gu, Yu-Duo Hao, ... Hao Lv in BMC Biology
    Article Open access 19 April 2024
  4. A novel meta-analysis based on data augmentation and elastic data shared lasso regularization for gene expression

    Background

    Gene expression analysis can provide useful information for analyzing complex biological mechanisms. However, many reported findings are...

    Hai-Hui Huang, Hao Rao, ... Yong Liang in BMC Bioinformatics
    Article Open access 23 August 2022
  5. Identification of geographical origin and adulteration of Northeast China soybeans by mid-infrared spectroscopy and spectra augmentation

    Mathematical models based on infrared spectroscopy and machine learning have been successfully used to trace the origin of soybeans. However, as...

    Yuhui **ao, Honghao Cai, Hui Ni in Journal of Consumer Protection and Food Safety
    Article 19 December 2023
  6. A deep learning framework for predicting disease-gene associations with functional modules and graph augmentation

    Background

    The exploration of gene-disease associations is crucial for understanding the mechanisms underlying disease onset and progression, with...

    **anghu Jia, Weiwen Luo, ... **aoquan Su in BMC Bioinformatics
    Article Open access 14 June 2024
  7. Untangling the contribution of active and passive group augmentation benefits to the multilevel selection of altruism using a video game

    The group augmentation hypothesis states that individuals gain benefits by increasing group size and is rarely studied because it often overlaps with...

    Julien Céré, Clint D Kelly, Pierre-Olivier Montiglio in Behavioral Ecology and Sociobiology
    Article 05 June 2024
  8. UnMICST: Deep learning with real augmentation for robust segmentation of highly multiplexed images of human tissues

    Upcoming technologies enable routine collection of highly multiplexed (20–60 channel), subcellular resolution images of mammalian tissues for...

    Clarence Yapp, Edward Novikov, ... Peter K. Sorger in Communications Biology
    Article Open access 18 November 2022
  9. The integration of metabolic and proteomic data uncovers an augmentation of the sphingolipid biosynthesis pathway during T-cell differentiation

    Recent studies have highlighted the significance of cellular metabolism in the initiation of clonal expansion and effector differentiation of T...

    Toshio Kanno, Ryo Konno, ... Yusuke Endo in Communications Biology
    Article Open access 23 May 2024
  10. Gender specific SNP markers in Coscinium fenestratum (Gaertn.) Colebr. for resource augmentation

    Background

    Unregulated extraction of highly traded medicinal plant species results in drastic decline of the natural resources and alters viable sex...

    Remya Unnikrishnan, Swathi Balakrishnan, ... Suma Arun Dev in Molecular Biology Reports
    Article 09 January 2024
  11. Automated neuron tracking inside moving and deforming C. elegans using deep learning and targeted augmentation

    Reading out neuronal activity from three-dimensional (3D) functional imaging requires segmenting and tracking individual neurons. This is challenging...

    Core Francisco Park, Mahsa Barzegar-Keshteli, ... Sahand Jamal Rahi in Nature Methods
    Article 05 December 2023
  12. Retinal organoids with X-linked retinoschisis RS1 (E72K) mutation exhibit a photoreceptor developmental delay and are rescued by gene augmentation therapy

    Background

    X-linked juvenile retinoschisis (XLRS) is an inherited disease caused by RS1 gene mutation, which leads to retinal splitting and visual...

    Chunwen Duan, Chengcheng Ding, ... Shibo Tang in Stem Cell Research & Therapy
    Article Open access 31 May 2024
  13. PDA-PRGCN: identification of Piwi-interacting RNA-disease associations through subgraph projection and residual scaling-based feature augmentation

    Background

    Emerging evidences show that Piwi-interacting RNAs (piRNAs) play a pivotal role in numerous complex human diseases. Identifying potential...

    ** Zhang, Weicheng Sun, ... Li Li in BMC Bioinformatics
    Article Open access 17 January 2023
  14. Current Perspectives and Progress in Preoperative Portal Vein Embolization with Stem Cell Augmentation (PVESA)

    Portal vein embolization with stem cell augmentation (PVESA) is an emerging approach for enhancing the growth of the liver segment that will remain...

    Allan John R. Barcena, Tyler C. Owens, ... Steven Y. Huang in Stem Cell Reviews and Reports
    Article Open access 13 April 2024
  15. MVGCNMDA: Multi-view Graph Augmentation Convolutional Network for Uncovering Disease-Related Microbes

    Motivation:

    Exploring the interrelationships between microbes and disease can help microbiologists make decisions and plan treatments. Predicting new...

    Meifang Hua, Shengpeng Yu, ... Hong Wang in Interdisciplinary Sciences: Computational Life Sciences
    Article 15 April 2022
  16. Which data subset should be augmented for deep learning? a simulation study using urothelial cell carcinoma histopathology images

    Background

    Applying deep learning to digital histopathology is hindered by the scarcity of manually annotated datasets. While data augmentation can...

    Yusra A. Ameen, Dalia M. Badary, ... Adel A. Sewisy in BMC Bioinformatics
    Article Open access 03 March 2023
  17. Estimation and Inference for Individualized Treatment Rules Using Efficient Augmentation and Relaxation Learning

    Individualized treatment rules aim to identify the best strategy—if, when, which, and to whom treatment should be applied, to optimize the health...
    Muxuan Liang, Ying-Qi Zhao in Statistics in Precision Health
    Chapter 2024
  18. Current Approaches in Vertical Bone Augmentation and Large Bone Deficiencies in the Orofacial Region

    Bone regeneration in the orofacial region is a significant health and economic burden. While surgical techniques for the treatment of bone...
    Cedryck Vaquette, Saso Ivanovski, Martin Batstone in Regenerative Medicine
    Chapter 2023
  19. Boric Acid (Boron) Attenuates AOM-Induced Colorectal Cancer in Rats by Augmentation of Apoptotic and Antioxidant Mechanisms

    Boric acid (BA) is a naturally occurring weak Lewis acid containing boron, oxygen, and hydrogen elements that can be found in water, soil, and...

    Ahmed A. J. Jabbar, Zaenah Zuhair Alamri, ... Yahya A. Almutawif in Biological Trace Element Research
    Article 29 September 2023
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