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DNA Methylation in Ctenophores
Epigenomic regulation and dynamic DNA methylation, in particular, are widespread mechanisms orchestrating the genome operation across time and...
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Phasing DNA Methylation
Haploty** enables the study of allele-specific events. Heterozygous variants, primarily single nucleotide variants (SNVs), enable the assignment of...
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DNA Methylation Analysis Using Bisulfite Pyrosequencing
Pyrosequencing is a DNA sequencing-by-synthesis technique that can quantitatively detect single-nucleotide polymorphisms (SNPs). With pyrosequencing,...
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DNA Methylation Data Analysis Using Msuite
DNA methylation is a widespread epigenetic modification responsible for many biological regulation pathways. The development of various powerful...
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Evolution and Diversity of DNA Methylation in Eukaryotes
DNA methylation (DNAm) is an important and well characterized epigenetic process which regulates gene expression, plays a vital role in embryonic...
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A Brief Introduction to Diet and DNA Methylation
Epigenetic regulatory mechanisms, which include DNA methylation, histone modifications, and non-coding RNA pathways, are independent of DNA sequence...
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DNA Methylation Analysis of Cnr1 Gene Promoter
DNA methylation pattern could be considered a biomarker to be exploited for the study and management of several human diseases. In this chapter,...
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Targeted DNA Methylation in Mouse Early Embryos
In germ cell lines, including early preimplantation embryos, centromeres and pericentromeres are known to show a marked hypomethylation pattern...
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Estimating genome-wide DNA methylation heterogeneity with methylation patterns
BackgroundIn a heterogeneous population of cells, individual cells can behave differently and respond variably to the environment. This cellular...
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Small RNA and DNA Methylation of Tea Plants
Small RNAs are a category of short noncoding RNAs (ncRNAs) with 18–30 nt lengths. Based on their function and mechanisms of biogenesis, these small...
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Interactive DNA Methylation Array Analysis with ShinyÉPICo
Arrays provide a cost-effective platform for the analysis of human DNA methylation. ShinyÉPICo is an interactive, web-based, and graphical tool that...
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Single-cell DNA methylation sequencing by combinatorial indexing and enzymatic DNA methylation conversion
BackgroundDNA methylation is a critical molecular mark involved in cellular differentiation and cell-specific processes. Single-cell whole genome DNA...
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Methylation-Specific Electrophoresis
Methylation of CpG sites in the promoter region of genomic DNA is an important epigenetic modification that plays a critical role in gene regulation,...
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DNA Methylation in Prokaryotes
The genomes of bacteria, archaea, and phage contain small amounts of C5-methylcytosine, N4-methylcytosine, and N6-methyladenine. Base methylation...
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Inhibitors of DNA Methylation
DNA methylation is involved in numerous biological processes and is deregulated in human diseases. The modulation of the activity of the enzymes and...
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DNA methylation in poultry: a review
As an important epigenetic modification, DNA methylation is involved in many biological processes such as animal cell differentiation, embryonic...
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Repeat DNA methylation is modulated by adherens junction signaling
Through its involvement in gene transcription and heterochromatin formation, DNA methylation regulates how cells interact with their environment....
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Efficient Targeted DNA Methylation with dCas9-Coupled DNMT3A-DNMT3L Methyltransferase
Epigenome editing is a powerful approach for the establishment of a chromatin environment with desired properties at a selected genomic locus, which...
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Single-molecule long-read methylation profiling reveals regional DNA methylation regulated by Elongator Complex Subunit 2 in Arabidopsis roots experiencing spaceflight
BackgroundThe Advanced Plant Experiment-04 - Epigenetic Expression (APEX-04-EpEx) experiment onboard the International Space Station examined the...
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The impact of DNA methylation on CTCF-mediated 3D genome organization
Cytosine DNA methylation is a highly conserved epigenetic mark in eukaryotes. Although the role of DNA methylation at gene promoters and repetitive...
