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Enhancement of Prebiotic Peptide Formation in Cyclic Environments
The dynamic behaviors of prebiotic reaction networks may be critically important to understanding how larger biopolymers could emerge, despite being...
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Molecular Identification of the Cyclic Peptide Hepatotoxins in Cyanobacteria
Various cyanobacteria can produce cyclic peptide hepatotoxins such as Microcystin and Nodularin. Cyanobacterial orders, Oscillatoriales,...
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Discovery of Cyclic Peptide Binders from Chemically Constrained Yeast Display Libraries
Cyclic peptides with engineered protein-binding activity have great potential as therapeutic and diagnostic reagents owing to their favorable...
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Peptide-Mediated Cyclic Nucleotide Signaling in Plants: Identification and Characterization of Interactor Proteins with Nucleotide Cyclase Activity
During the last decades, an increasing number of plant signaling peptides have been discovered and it appears that many of them are specific ligands...
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Cyclic Dodecapeptide Induces Cell Death Through Membrane–Peptide Interactions in Breast Cancer Cells
Antimicrobial peptides (AMPs) are present in many organisms ranging from insects to mammals. They have a selectivity as cationic and amphiphilic...
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Antimicrobial Peptide Nanomaterials
Antimicrobial peptides exist throughout nature and are produced by multicellular organisms as a defence mechanism against pathogenic microbes....
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Multifunctional Peptide Biointerfaces
In creating useful devices for biomedical and other applications that come into contact with biological fluids, it is of great interest to mimic the...
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Peptide Amphiphile Nanomaterials
Peptide amphiphiles (PAs) have emerged as an essential class of peptides, particularly in the bottom-up fabrication of innovative soft materials....
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A Review: The Antiviral Activity of Cyclic Peptides
In the design and development of therapeutic agents, macromolecules with restricted structures have stronger competitive edges than linear biological...
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Chirality in Peptide Self-Assembly and Aggregation
Peptide self-assembly is relevant to the formation of functional and dysfunctional biological structures and has also been used in the fabrication of...
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Ultra-Short Peptide Nanomaterials
In the analysis of the materials formed by short peptides, we need to define what we mean by short, as the determination of “short peptide” has not...
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Enhancing the Stability of Tumor Homing LyP-1 Peptide Using Cyclization and Retro Grafting Strategies
Anticancer peptide therapeutics are promising candidates for cancer treatment as they are highly specific to their targets and can have tumor-homing...
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Design Rules for Self-Assembling Peptide Nanostructures
Self-assembling peptides represent a versatile chemical toolbox for the development of discrete nanostructures that can be tailored for a variety of...
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Modulation of Voltage Sensitivity of Slow Sodium Channels by a Synthetic Cyclic Peptide
AbstractEffects of a synthetic cyclic peptide on the primary sensory neuron responses are investigated. A decrease in the Na V 1.8 channel voltage...
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Peptide Conjugation Methods and Protocols
This volume explores diverse protocols for peptide conjugation, and provides thoroughly tested and scientifically valid techniques that allow...
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Evolution of Peptide Drug Biopharmaceutics
Abstract—Peptides are low-molecular-weight substances involved in numerous physiological processes, such as growth and development of the organism,...
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β-Sheet and β-Hairpin Peptide Nanomaterials
Supramolecular peptide assemblies have emerged as promising next-generation nanomaterials for applications in medicine, tissue engineering, and...
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Bioproduction of Cyclic Disulfide-Rich Peptides for Drug Modalities
Cyclic disulfide-rich peptides have extensive applications in drug development. These peptides are widely produced using solid-phase peptide...
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The Construction of a Genetically Encoded, Phage-Displayed Cyclic-Peptide Library
Due to the great potentials of cyclic peptides as therapeutic agents, several phage-displayed peptide libraries in which cyclization is achieved by...
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Structural Studies of Modular Nonribosomal Peptide Synthetases
The non-ribosomal peptide synthetases (NRPSs) are a family of modular enzymes involved in the production of peptide natural products. Not restricted...