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Survival time prediction by integrating cox proportional hazards network and distribution function network
BackgroundThe Cox proportional hazards model is commonly used to predict hazard ratio, which is the risk or probability of occurrence of an event of...
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A transformer model for cause-specific hazard prediction
BackgroudModelling discrete-time cause-specific hazards in the presence of competing events and non-proportional hazards is a challenging task in...
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ResDeepSurv: A Survival Model for Deep Neural Networks Based on Residual Blocks and Self-attention Mechanism
AbstractSurvival analysis, as a widely used method for analyzing and predicting the timing of event occurrence, plays a crucial role in the medicine...
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The survival analysis of some environmental factors associated with lamb mortality in Awassi sheep
Most of the economic losses in the Turkish sheep industry are due to lamb deaths between birth and weaning period. Survival analysis is an essential...
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Machine Learning Methods for Survival Analysis with Clinical and Transcriptomics Data of Breast Cancer
Breast cancer is one of the most common cancers in women worldwide, which causes an enormous number of deaths annually. However, early diagnosis of...
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Deep learning model integrating positron emission tomography and clinical data for prognosis prediction in non-small cell lung cancer patients
BackgroundLung cancer is the leading cause of cancer-related deaths worldwide. The majority of lung cancers are non-small cell lung cancer (NSCLC),...
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Identification and validation of a DNA methylation-driven gene-based prognostic model for clear cell renal cell carcinoma
BackgroundClear cell renal cell carcinoma (ccRCC) is a malignant tumor with heterogeneous morphology and poor prognosis. This study aimed to...
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Nonlinear connection between remnant cholesterol and stroke risk: evidence from the China health and retirement longitudinal study
ObjectiveThe evidence on the relationship between remnant cholesterol (RC) and stroke remains controversial. Therefore, this study aimed to explore...
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PATH-SURVEYOR: pathway level survival enquiry for immuno-oncology and drug repurposing
Pathway-level survival analysis offers the opportunity to examine molecular pathways and immune signatures that influence patient outcomes. However,...
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Risk factor analysis and risk prediction study of obesity in steelworkers: model development based on an occupational health examination cohort dataset
BackgroundObesity is increasingly recognized as a grave public health concern globally. It is associated with prevalent diseases including coronary...
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The therapeutic and prognostic role of cuproptosis-related genes in triple negative breast cancer
BackgroundThis study aimed to observe the potential impact of known cuproptosis-related genes (CRGs) on triple negative breast cancer (TNBC)...
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Effect of Chronic Kidney Disease on All-Cause Mortality After Hip Fracture Surgery: A Retrospective Cohort Study
In this retrospective cohort study, we investigated: (1) The impact of comorbid chronic kidney disease (CKD) on postoperative mortality in patients...
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Associations of Whole Blood Zinc Levels with Coronary Artery Calcification and Future Cardiovascular Events in CKD Patients
This study was conducted to compare the differences of the whole blood zinc concentration in patients with chronic kidney disease (CKD) as compared...
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Assessment of a polygenic hazard score for the onset of pre-clinical Alzheimer’s disease
Abstract BackgroundWith a growing number of loci associated with late-onset (sporadic) Alzheimer’s disease (AD), the polygenic contribution to AD is...
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Ecological factors influencing invasive predator survival and movement: insights from a continental-scale study of feral cats in Australia
Feral cats ( Felis catus ) pose a significant global threat to biodiversity, primarily through predation, disease and competition. A key gap in...
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The neutrophil-to-apolipoprotein A1 ratio is associated with adverse outcomes in patients with acute decompensated heart failure at different glucose metabolic states: a retrospective cohort study
BackgroundThe present study was performed to assess the association between the neutrophil-to-apolipoprotein A1 ratio (NAR) and outcomes in patients...
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Disease staging of Alzheimer’s disease using a CSF-based biomarker model
Biological staging of individuals with Alzheimer’s disease (AD) may improve diagnostic and prognostic workup of dementia in clinical practice and the...
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Clinical biomarker-based biological age predicts deaths in Brazilian adults: the ELSA-Brasil study
Biological age is a construct that seeks to evaluate the biological wear and tear process of the organism that cannot be observed by chronological...
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Associations between serum ferritin baselines and trajectories and the incidence of metabolic dysfunction-associated steatotic liver disease: a prospective cohort study
Background and aimsEvidence from prospective cohort studies on the relationship between metabolic dysfunction-associated steatotic liver disease...
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Relationship between early-onset stroke and triglyceride-glucose index among young Chinese adults
BackgroundThe triglyceride–glucose index (TyG index), an alternative indicator of peripheral insulin resistance (IR), is associated with...
