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Identification of inhibitors targeting the energy-coupling factor (ECF) transporters
The energy-coupling factor (ECF) transporters are a family of transmembrane proteins involved in the uptake of vitamins in a wide range of bacteria....
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Classical and Quantum Mechanochemical Coupling
In this chapter, we apply the results obtained in Chaps. 1 and 2...
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Plant Multi-element Coupling as an Indicator of Nutritional Mismatches Under Global Change
Global biogeochemical cycles have been widely altered due to human activities, potentially compromising the ability of plants to regulate their...
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Dynamic carbon-nitrogen coupling under global change
Carbon-nitrogen coupling is a fundamental principle in ecosystem ecology. However, how the coupling responds to global change has not yet been...
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The structural–functional-connectivity coupling of the aging brain
Aging primarily affects memory and executive functions, a relationship that may be underpinned by the fact that almost all adults over 60 years old...
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Hedgehog signaling regulates bone homeostasis through orchestrating osteoclast differentiation and osteoclast–osteoblast coupling
Imbalance of bone homeostasis induces bone degenerative diseases such as osteoporosis. Hedgehog (Hh) signaling plays critical roles in regulating the...
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Synthesis of propargylamine: pioneering a green path with non-conventional KA2 coupling approach
The KA 2 coupling reaction is a well-explored and versatile method for forming C–C bonds in synthetic chemistry. It is composed of ketone, amine, and...
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Alzheimer’s disease rewires gene coexpression networks coupling different brain regions
Connectome studies have shown how Alzheimer’s disease (AD) disrupts functional and structural connectivity among brain regions. But the molecular...
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MiRNAs regulate cell communication in osteogenesis-angiogenesis coupling during bone regeneration
Bone regeneration is a complex process that requires not only the participation of multiple cell types, but also signal communication between cells....
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Generation of Gαi knock-out HEK293 cells illuminates Gαi-coupling diversity of GPCRs
G-protein-coupled receptors (GPCRs) are pivotal cell membrane proteins that sense extracellular molecules and activate cellular responses. The...
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Coupling Coordination of Green Sugarcane Production and Comprehensive Social Development in Chinese Sugar Industry
Coordinated development of green production in sugarcane industry and the economy of the main producing areas is vital for scientifically formulating...
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Global Environmental Change Shifts Ecological Stoichiometry Coupling Between Plant and Soil in Early-Stage Invasions
Extensive research has been conducted on the ecological stoichiometry of plants and soils. However, the relationship between plants and soil...
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Air-water-fertilizer-coupling Drip Irrigation Facilitates Lettuce Growth by Sha** Rhizosphere Microbiome Associated with Soil Nutrient Cycling
Air-water-fertilizer-coupling drip irrigation is an emerging technique to promote crop growth by improving soil properties. How the rhizosphere...
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Glymphatic-lymphatic coupling: assessment of the evidence from magnetic resonance imaging of humans
The discoveries that cerebrospinal fluid participates in metabolic perivascular exchange with the brain and further drains solutes to meningeal...
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New Insights for the Renewed Phytoplankton-Bacteria Coupling Concept: the Role of the Trophic Web
It is widely accepted that in many aquatic ecosystems bacterioplankton is dependent on and regulated by organic carbon supplied by phytoplankton,...
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An experimental and numerical study on the coupling effect of CLT wall-to-floor angle bracket connections
Cross-laminated timber (CLT) wall panels are commonly connected to the floor or foundation using metal connections, which play a critical role in...
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A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways
The ten Frizzled receptors (FZDs) are essential in Wnt signaling and play important roles in embryonic development and tumorigenesis. Among these,...
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Boosting working memory in the elderly: driving prefrontal theta–gamma coupling via repeated neuromodulation
The escalating global burden of age-related neurodegenerative diseases and associated healthcare costs necessitates innovative interventions to...
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Instructor-learner body coupling reflects instruction and learning
It is widely accepted that nonverbal communication is crucial for learning, but the exact functions of interpersonal coordination between instructors...
