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Top-down and bottom-up coupling effects of subsidies on recipient ecosystems
A subsidy can directly enter a recipient ecosystem by either being consumed or being recycled to the nutrient pool with both pathways causing...
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Plant Multi-element Coupling as an Indicator of Nutritional Mismatches Under Global Change
Global biogeochemical cycles have been widely altered due to human activities, potentially compromising the ability of plants to regulate their...
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Structural basis of tethered agonism and G protein coupling of protease-activated receptors
Protease-activated receptors (PARs) are a unique group within the G protein-coupled receptor superfamily, orchestrating cellular responses to...
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Inter-brain coupling reflects disciplinary differences in real-world classroom learning
The classroom is the primary site for learning. A vital feature of classroom learning is the division of educational content into various...
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Glymphatic-lymphatic coupling: assessment of the evidence from magnetic resonance imaging of humans
The discoveries that cerebrospinal fluid participates in metabolic perivascular exchange with the brain and further drains solutes to meningeal...
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An experimental and numerical study on the coupling effect of CLT wall-to-floor angle bracket connections
Cross-laminated timber (CLT) wall panels are commonly connected to the floor or foundation using metal connections, which play a critical role in...
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A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways
The ten Frizzled receptors (FZDs) are essential in Wnt signaling and play important roles in embryonic development and tumorigenesis. Among these,...
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Instructor-learner body coupling reflects instruction and learning
It is widely accepted that nonverbal communication is crucial for learning, but the exact functions of interpersonal coordination between instructors...
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Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution
Channel enzymes represent a class of ion channels with enzymatic activity directly or indirectly linked to their channel function. We investigated a...
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Longitudinal aortic strain, ventriculo-arterial coupling and fatty acid oxidation: novel insights into human cardiovascular aging
AbstractAging-induced aortic stiffness has been associated with altered fatty acid metabolism. We studied aortic stiffness using cardiac magnetic...
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Coupling strength between omnivory loops and their one-species-delete subloops drives real food web stability
A central and fundamental issue in ecology is to understand the relationship between complexity and stability. Increased empirical evidences...
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Genome Characteristic of Bordetella parapertussis Isolated from Iran
Pertussis also known as whoo** cough is a respiratory infection in humans particularly with severe symptoms in infants and usually caused by Bordetel...
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The coupling mechanism of mammalian mitochondrial complex I
Mammalian respiratory complex I (CI) is a 45-subunit, redox-driven proton pump that generates an electrochemical gradient across the mitochondrial...
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Identification and Analysis of Characteristic Flavour Compounds in Baked Potato of Different Cultivars Based on HS-GC-IMS
In this study, the volatile flavour compounds of baked potatoes from different cultivars were identified and analysed via headspace–gas...
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Cytosolic peptides encoding CaV1 C-termini downregulate the calcium channel activity-neuritogenesis coupling
L-type Ca 2+ (Ca V 1) channels transduce channel activities into nuclear signals critical to neuritogenesis. Also, standalone peptides encoded by Ca V 1...
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Local and Systemic Regulation of Mineralization: Role of Coupling Factors, Pyrophosphate, Polyphosphates, Vitamin D, Fetuin, Matrix Gla Protein, and Osteopontin
The chapter addresses mechanisms by which inhibitory factors regulate hard tissue deposition and explains how bone cells collectively control new... -
Cytoophidia coupling adipose architecture and metabolism
Tissue architecture determines its unique physiology and function. How these properties are intertwined has remained unclear. Here we show that the...
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Visualizing the native cellular organization by coupling cryofixation with expansion microscopy (Cryo-ExM)
Cryofixation has proven to be the gold standard for efficient preservation of native cell ultrastructure compared to chemical fixation, but this...
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Cross-coupling reactions towards the synthesis of natural products
AbstractCross-coupling reactions are powerful synthetic tools for the formation of remarkable building blocks of many naturally occurring molecules,...
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Characteristic structural difference between inactive and active states of orexin 2 receptor determined using molecular dynamics simulations
To investigate the dynamics of the orexin 2 receptor, which is a class A G protein-coupled receptor, we recently performed several microsecond-scale...