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Immune imprinting and next-generation coronavirus vaccines
Vaccines based on historical virus isolates provide limited protection from continuously evolving RNA viruses, such as influenza viruses or...
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Mechanisms of Kidney Damage Development in Patients with New Coronavirus Infection: Literature Review
AbstractEvery fourth person in the world currently has kidney problems to one or another degree. It is known that the novel coronavirus infection...
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LY6E is a pan-coronavirus restriction factor in the respiratory tract
LY6E is an antiviral restriction factor that inhibits coronavirus spike-mediated fusion, but the cell types in vivo that require LY6E for protection...
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ACP-Dnnel: anti-coronavirus peptides’ prediction based on deep neural network ensemble learning
The ongoing COVID-19 pandemic has caused dramatic loss of human life. There is an urgent need for safe and efficient anti-coronavirus infection...
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Biology of the SARS-CoV-2 Coronavirus
AbstractNew coronavirus infection causing COVID-19, which was first reported in late 2019 in China, initiated severe social and economic crisis that...
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Antiviral and Cytoprotective Effect of Zinc (Yasad Bhasma) Based Nanoformulations Against Bovine Coronavirus
Ayurvedic medicine utilizes metal-based preparations, known as bhasmas, to treat various health conditions. Yasad bhasma (YB), a zinc-based ayurvedic...
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MERS-Coronavirus (MERS)
This chapter briefly presents some structural bioinformatics about MERS-CoVMERS-CoV binding with human ACE2. We find in the middle of interactions...
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STING agonists as promising vaccine adjuvants to boost immunogenicity against SARS-related coronavirus derived infection: possible role of autophagy
As a major component of innate immunity and a positive regulator of interferons, the Stimulator of interferon gene (STING) has an immunotherapy...
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Hemoglobin Affinity to Oxygen during Coronavirus Infection: New Faces of a Known Problem
AbstractThe development of coronavirus infection prevents the transport of oxygen to the tissues through the mechanism of impaired...
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Effect of nanosecond pulsed electric fields (nsPEFs) on coronavirus survival
Previous work demonstrated inactivation of influenza virus by GHz frequency electromagnetic fields. Despite theoretical and experimental results, the...
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Epilog: Die Pandemie als große Offenbarung – Coronavirus, Stress und Armut
Jegliche ab dem Jahr 2020 veröffentlichte Studie über Stress und Armut wird die durch das Coronavirus SARS-CoV-2 ausgelöste Pandemie nur schwer...
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Nucleic acid-based vaccine platforms against the coronavirus disease 19 (COVID-19)
The coronavirus disease 2019 (COVID-19) pandemic has infected 673,010,496 patients and caused the death of 6,854,959 cases globally until today....
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Plant-Derived Compounds with Therapeutic Potential for the Treatment of Human Coronavirus Diseases
Since the advent of modern civilization, few diseases have caused more worldwide socioeconomic disruptions than COVID-19 caused by severe acute...
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Neurotropism as a Mechanism of the Damaging Action of Coronavirus
Abstract —Clinical evidence suggests that COVID-19 is accompanied by many symptoms of damage to the central and peripheral nervous system. This...
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A pan-coronavirus peptide inhibitor prevents SARS-CoV-2 infection in mice by intranasal delivery
Coronaviruses (CoVs) have brought serious threats to humans, particularly severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2), which...
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Coronavirus sampling and surveillance in bats from 1996–2019: a systematic review and meta-analysis
The emergence of SARS-CoV-2 highlights a need for evidence-based strategies to monitor bat viruses. We performed a systematic review of coronavirus...
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Inflammatory cell death, PANoptosis, screen identifies host factors in coronavirus innate immune response as therapeutic targets
The COVID-19 pandemic, caused by the β-coronavirus (β-CoV) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to cause...
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Targeting papain-like protease for broad-spectrum coronavirus inhibition
The emergence of SARS-CoV-2 variants of concern and repeated outbreaks of coronavirus epidemics in the past two decades emphasize the need for...
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Stabilization of Full-Length S-Protein of SARS-Cov-2 Coronavirus in SMA Polymer for Electron Microscopy Study
AbstractA detergent-free protocol for purification of the coronavirus prefusion S-protein using styrene-maleic acid copolymer (SMA) was developed....
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