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Cold-inducible RNA binding protein alleviates iron overload-induced neural ferroptosis under perinatal hypoxia insult
Cold-inducible RNA binding protein (CIRBP), a stress response protein, protects cells from mild hypothermia or hypoxia by stabilizing specific mRNAs...
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Overexpressed cold inducible RNA-binding protein improves cell viability and EGF expression in glial cells
BackgroundCold inducible RNA-binding protein (CIRP) is a key protein in the hypothermic therapy. Highly expressed CIRP exerts a neuroprotective...
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Molecular characterization and expression analysis of a novel cold-inducible RNA-binding protein (CIRBP) gene in lamprey (Lethenteron reissneri)
Cold-inducible RNA-binding protein (CIRBP) responds to a wide array of cellular stresses such as cold shock, hypoxia, and inflammatory responses....
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Core promoter mutation of nucleotides A1762T and G1764A of hepatitis B virus increases core promoter transactivation by hepatocyte nuclear factor 1
Hepatitis B virus (HBV) infection highly increases the risk for liver cirrhosis and hepatocellular carcinoma (HCC). The clinical manifestation of HBV...
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Human Heme Oxygenase-1 Promoter Activity Is Mediated by Z-DNA Formation
In recent years, it has been shown that Z-DNA formation in DNA plays functionally significant roles in nucleic acid metabolism, such as gene...
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Molecular Cloning and Functional Analysis of ScHAK10 Gene Promoter from Sugarcane (Saccharum officinarum L.)
Transcriptional regulation of the high-affinity K + ( HAK ) transporter gene is an important mechanism of plant response to low potassium stress....
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Cellular reprogramming is driven by widespread rewiring of promoter-enhancer interactions
BackgroundLong-range interactions between promoters and cis -regulatory elements, such as enhancers, play critical roles in gene regulation. However,...
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Novel inducible promoter DREB1G cloned from date palm exhibits high fold expression over AtRD29 to drought and salinity stress
Right and timely expression of the stress regulatory genes is required for plants to compete against abiotic stresses; it necessitates the isolation...
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Characterization of wheat Wrab18 gene promoter and expression analysis under abiotic stress
BackgroundPromoters play key roles in plant gene expression in complex and varied natural environments. The type and amount of cis -acting elements...
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Synthetic sub-genomic transcript promoter from Horseradish Latent Virus (HRLV)
Main conclusionWe characterized an efficient chimeric sub-genomic transcript promoter from Horseradish Latent Virus, FHS4, active in both dicot and...
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Identification of Stigma Specific Expression Fragment in the Promoter of a Soybean Chitinase Class I Gene
AbstractThe expression level of heterologous genes in transgenic plants serves as an important indicator of gene efficiency. The small number of...
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Functional analysis of recurrent CDC20 promoter variants in human melanoma
Small nucleotide variants in non-coding regions of the genome can alter transcriptional regulation, leading to changes in gene expression which can...
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Isolation and characterization of drought and ABA responsive promoter of a transcription factor encoding gene from rice
Water deficit is a significant impediment to enhancing rice yield. Genetic engineering tools have enabled agriculture researchers to develop...
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Isolation and characterization of wheat ice recrystallisation inhibition gene promoter involved in low temperature and methyl jasmonate responses
It is well known that plant growth, development, survival and geographical distribution are constrained by extreme climatic conditions, especially...
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Cloning and functional analysis of the PLkF3H2 promoter in Larix kaempferi
The flavanone 3-hydroxy-lase2 ( F3H2 ) gene is one of the key genes in flavonoid biosynthesis pathways in Larix kaempferi (Lam.) Carrière (Japanese...
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Cloning and characterization of the BZR1-2 promoter from Camellia sinensis and its responses to hormonal and abiotic stresses
Tea plant ( Camellia sinensis (L.) O. Kuntze) is an important woody economic crop that has been cultivated worldwide. Adversity stress acts as a...
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Promoter activity and transcriptome analyses decipher functions of CgbHLH001 gene (Chenopodium glaucum L.) in response to abiotic stress
BackgroundOur previous studies revealed that CgbHLH001 transcription factor (TF) played an important role in abiotic stress tolerance, suggesting...
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Enhancement of recombinant human keratinocyte growth factor 1 protein production in transgenic hazelnut (Corylus avellana L.) plant cell suspension cultures under RAmy3D inducible promoter
Recombinant human KGF1 (rhKGF) is a fibroblast growth factor that promotes epidermal cell proliferation, differentiation, migration, and wound...
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Functional Characterization of Salt‑Stress Induced Rare Cold Inducible Gene from Camelina sativa (CsRCI2D)
Rare-cold-inducible 2 ( RCI2 ) genes are involved in plant response to abiotic stresses. In this study, we report the functional role of a Camelina ...
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The HASTER lncRNA promoter is a cis-acting transcriptional stabilizer of HNF1A
The biological purpose of long non-coding RNAs (lncRNAs) is poorly understood. Haploinsufficient mutations in HNF1A homeobox A ( HNF1A ), encoding a...
