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Effect of Chronic Kidney Disease on All-Cause Mortality After Hip Fracture Surgery: A Retrospective Cohort Study
In this retrospective cohort study, we investigated: (1) The impact of comorbid chronic kidney disease (CKD) on postoperative mortality in patients...
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Interactive effect of increased high sensitive C-reactive protein and dyslipidemia on cardiovascular diseases: a 12-year prospective cohort study
BackgroundDyslipidemia and inflammation are significant factors for the onset of cardiovascular diseases (CVD); however, studies regarding their...
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An exploratory investigation of the CSF metabolic profile of HIV in a South African paediatric cohort using GCxGC-TOF/MS
IntroductionBecause cerebrospinal fluid (CSF) samples are difficult to obtain for paediatric HIV, few studies have attempted to profile...
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Identification and validation of microbial biomarkers from cross-cohort datasets using xMarkerFinder
Microbial signatures have emerged as promising biomarkers for disease diagnostics and prognostics, yet their variability across different studies...
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Genome-wide association identifies novel ROP risk loci in a multiethnic cohort
We conducted a genome-wide association study (GWAS) in a multiethnic cohort of 920 at-risk infants for retinopathy of prematurity (ROP), a major...
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Sex differences in DNA methylation across gestation: a large scale, cross-cohort, multi-tissue analysis
Biological sex is a key variable influencing many physiological systems. Disease prevalence as well as treatment success can be modified by sex....
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High remnant-cholesterol levels increase the risk for end-stage renal disease: a nationwide, population-based, cohort study
BackgroundThe effect of remnant-cholesterol (remnant-C) on incident end-stage renal disease (ESRD) has not been studied longitudinally. This...
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Autonomic dysfunction is associated with the development of arterial stiffness: the Whitehall II cohort
This study aims to examine the association between baseline level and change of autonomic nervous function with subsequent development of arterial...
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A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality
The associations between social isolation, loneliness and the risk of mortality from all causes, cardiovascular disease (CVD) and cancer are...
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Schnitzler’s Syndrome—Diagnostic Experience, Approaches to Therapy, and Patient Management according to a Multicenter Russian Cohort
AbstractThe objectives of the study were to present the experience of diagnosis, management, and therapy with IL-1 inhibitors in patients with...
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Phenotypic Evolution in Fabry Disease: Our Experience in Indian Cohort
The current study aimed to explore phenotypic evolution in Fabry disease according to demographics, genotype, specific enzyme activity and...
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eSVD-DE: cohort-wide differential expression in single-cell RNA-seq data using exponential-family embeddings
BackgroundSingle-cell RNA-sequencing (scRNA) datasets are becoming increasingly popular in clinical and cohort studies, but there is a lack of...
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Household immunity and individual risk of infection with dengue virus in a prospective, longitudinal cohort study
Although it is known that household infections drive the transmission of dengue virus (DENV), it is unclear how household composition and the immune...
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Dietary branched-chain amino acids intake and new-onset hypertension: a nationwide prospective cohort study in China
ObjectiveThis study aimed to investigate the relationship between dietary branched-chain amino acids (BCAAs) and the risk of develo** hypertension.
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Identification of risk factors and development of a predictive model for chronic kidney disease in patients with obesity: a four-year cohort study
ObjectiveThe sneaky onset and dismal prognosis of chronic kidney disease (CKD) make it an important public health issue. Obesity-related kidney...
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High-resolution structural variants catalogue in a large-scale whole genome sequenced bovine family cohort data
BackgroundStructural variants (SVs) are chromosomal segments that differ between genomes, such as deletions, duplications, insertions, inversions and...
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Fracture Risk and Health Profiles Differ According to Relationship Status: Findings from the Hertfordshire Cohort Study
Registry studies have suggested associations between relationship status and fracture risk. We considered associations between relationship status...
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Network prediction of surgical complication clusters: a prospective multicenter cohort study
Complicated relationships exist in both occurrence and progression of surgical complications, which are difficult to account for using a separate...
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Dietary Potassium and Magnesium Intake with Risk of Type 2 Diabetes Mellitus Among Rural China: the Henan Rural Cohort Study
Previous studies exploring the relationship between dietary potassium and magnesium intake and the risk of type 2 diabetes mellitus (T2DM) have...
