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Effects of co-administration of arsenic trioxide and Schiff base oxovanadium complex on the induction of apoptosis in acute promyelocytic leukemia cells
Acute promyelocytic leukaemia (APL) is commonly treated with arsenic trioxide (As2O3) that has many side effects. Given the increasing trend of...
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Some metal chelates with Schiff base ligand: synthesis, structure elucidation, thermal behavior, XRD evaluation, antioxidant activity, enzyme inhibition, and molecular docking studies
AbstractSchiff bases are well-known compounds for having significant biological properties. In this study, a new Schiff base ligand and its metal...
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Cytotoxic cobalt (III) Schiff base complexes: in vitro anti-proliferative, oxidative stress and gene expression studies in human breast and lung cancer cells
Increasing cancer drug chemo-resistance, especially in the treatment of breast and lung cancers, alarms the immediate need of newer and effective...
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A Brief Review on Schiff Base, Synthesis, and Their Antimicrobial Activities
AbstractThe Schiff base chemsitry includes compounds that attracted the attention of research scope from the early years. Consequently, the Schiff...
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Synthesis, Characterization, and Antioxidant Activity of a Novel Schiff Base, an Amine and Amine–Metal Complexes
AbstractIn this study, a new Schiff base ( 3 ) was synthesised from the reaction of the 4-aminoantipyridine ( 1 ) with 2-pyridine carboxaldehyde ( 2 )....
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Synthesis of biologically active cefpodoxime and vanillin-based schiff base metal complexes with the detailed biological evaluations
Schiff bases of existing antimicrobial drugs are an area, which is still to be comprehensively explored to improve drug efficiency against...
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Novel tetraaza macrocyclic Schiff base complexes of bivalent zinc: microwave-assisted green synthesis, spectroscopic characterization, density functional theory calculations, molecular docking studies, in vitro antimicrobial and anticancer activities
In the present manuscript, novel macrocyclic Schiff base complexes [Zn(N 4 MacL 1 )Cl 2 –Zn(N 4 MacL 3 )Cl 2 ] were synthesized by the reaction of ZnCl 2 and...
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Novel Cu(II) Schiff Base Complex Combination with Polymyxin B/Phenylalanine-Arginine β-Naphthylamide Against Various Bacterial Strains
Concerns on increasing trends of multidrug resistance (MDR) around the world have triggered the need to investigate and develop new therapeutic...
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Biomolecular docking interactions, cytotoxicity and antioxidant property evaluations with novel Mn(II), Ni(II), Cd(II) and Pb(II) Schiff base ligand complexes: Synthesis and characterization
The development of Schiff base-centered medical chemistry in conjunction with the use of less-expensive transition metals with high pharmacological...
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A novel Schiff base cobalt(III) complex induces a synergistic effect on cervical cancer cells by arresting early apoptosis stage
A new schiff base cobalt(III) complex [ N , N ′-bis(2′-hydroxyphenylacetone)-o-ethanediamine] cobalt(III) ( M3 ) has been synthesized and characterized by...
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Monitoring of singlet oxygen generation of a novel Schiff-base substituted silicon phthalocyanines by sono-photochemical studies and in vitro activities on prostate cancer cell
This study demonstrates the potential of sono-photodynamic therapy as an effective approach for enhancing singlet oxygen generation using the...
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Synthesis, theoretical studies, antibacterial, and antibiofilm activities of novel azo-azomethine chelates against the pathogenic bacterium Proteus mirabilis
2-((1-(4-((2,4,6-trioxohexahydropyrimidin-5-yl)diazenyl) phenyl) ethylidene) amino) benzoic acid (H 3 L), and its V(IV), Co(II), Ni(II), Cu(II), Pd(II)...
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Anti-tumor effect of novel amino acid Schiff base nickel (II) complexes on oral squamous cell carcinoma cells (CAL-27) in vitro
BackgroundOral squamous cell carcinoma (OSCC) is a common skin/oral malignant tumor. In recent years, advancements in the field of medical technology...
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A novel pyrazolone complex P-FAH-Cu-bpy induces death of Escherichia coli and Staphylococcus aureus by disrupting cell structure and blocking energy
A novel pyrazolone-based copper complex [Cu(L)(bpy)]∙CH3OH (P-FAH-Cu-bpy) was synthesized and previously characterized to have antitumor properties....
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Transition metal complexes of a multidentate Schiff base ligand containing pyridine: synthesis, characterization, enzyme inhibitions, antioxidant properties, and molecular docking studies
AbstractA series of Fe(II), Ni(II), and Pd(II) complexes were prepared with a novel Schiff base ligand containing pyridine moiety. The prepared...
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Facile synthesis, spectroscopic evaluation and antimicrobial screening of metal endowed triazole compounds
The scientific interest in develo** new complexes as inhibitors of bacterial biofilm related infections is constantly rising. The present work...
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Biosynthesis of Cu/KF/Clinoptilolite@MWCNTs nanocomposite and its application as a recyclable nanocatalyst for the synthesis of new Schiff base of benzoxazine derivatives and reduction of organic pollutants
AbstractIn this work, we synthesized new Schiff base of benzoxazine derivatives in excellent yields using multicomponent reactions of phthalaldehyde...
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The regulatory subunits of CK2 complex mediate DNA damage response and virulence in Candida Glabrata
BackgroundCandida glabrata which belongs to normal microbiota, has caused significant concern worldwide due to its high prevalence and drug...
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Antifungal potential of the new copper(II)-theophylline/1,10-phenanthroline complex against drug-resistant Candida species
Candida spp. are the commonest fungal pathogens worldwide. Antifungal resistance is a problem that has prompted the discovery of novel anti- Candida ...
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Unveiling the antifungal mechanisms of CTP, a new copper(II)-theophylline/1,10-phenanthroline complex, on drug-resistant non-albicans Candida species
Candida species undeniably rank as the most prevalent opportunistic human fungal pathogens worldwide, with Candida albicans as the predominant...
