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Novel citrinin derivatives from fungus Penicillium sp. TW131-64 and their antimicrobial activities
AbstractSix new citrinin derivatives ( 1 , 2 , 4 , 10 , 11 , and 16) , along with fourteen known analogues, were acquired from Penicillium sp. TW131-64, a...
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An oxidoreductase gene CtnD involved in citrinin biosynthesis in Monascus purpureus verified by CRISPR/Cas9 gene editing and overexpression
Monascus produces a kind of mycotoxin, citrinin, whose synthetic pathway is still not entirely clear. The function of CtnD , a putative oxidoreductase...
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Optimization of citrinin production by endophytic Penicillium citrinum isolated from Ziziphus jujuba
Citrinin is a common mycotoxin produced by different fungi. Although considerable endeavors have been made to increase citrinin output to meet the...
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Characterization and inhibition of four fungi producing citrinin in various culture media
PurposeThis study aimed to investigate the effects of different fermentation conditions (culture medium, temperature, incubation time, pH value and...
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Biomonitoring of ochratoxin A, 2′R-ochratoxin A and citrinin in human blood serum from Switzerland
Biomonitoring of mycotoxins and their metabolites in biological fluids is increasingly used to assess human exposure. In this study, biomarkers of...
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Subchronic exposure of individual and combined ochratoxin A and citrinin selectively affects the expression of rat renal organic cation transporters
Ochratoxin A (OTA) and citrinin (CIT) are nephrotoxins found co-occurring in various human/animal food/feed and recognized as a health threat....
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Inducing red pigment and inhibiting citrinin production by adding lanthanum(III) ion in Monascus purpureus fermentation
AbstractMonascus pigments (MPs) are widely used natural colorants in Asian countries. The problems of low extracellular red pigment (ERP) and high...
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Multiplex metabolic pathway engineering of Monascus pilosus enhances lovastatin production
AbstractMonascus sp. is an important food microbial resource with the production of cholesterol-lowering agent lovastatin and other healthy...
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Effects of some flavonoids on the mycotoxin citrinin reduction by Monascus aurantiacus Li AS3.4384 during liquid-state fermentation
Monascus can produce many beneficial metabolites; however, it can simultaneously also produce citrinin, which seriously limits its application....
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Mass Spectrometry Metabolomics Approach Reveals Anti-Trichomonas vaginalis Scaffolds from Marine Fungi
Trichomoniasis is the most common non-viral sexually transmitted infection (STI) in the world caused by Trichomonas vaginalis . Failures in the...
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Subchronic exposure to individual and combined ochratoxin A and citrinin affects the expression of rat renal organic anion transporters
Ochratoxin A (OTA) and citrinin (CIT) are mycotoxins known to co-contaminate human/animal food/feed. Their prominent nephrotoxic effects pose a...
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Anti-Klebsiella pneumoniae activity of secondary metabolism of Achromobacter from the intestine of Periplaneta americana
BackgroundKlebsiella pneumoniae is one of the main pathogens of clinical isolation and nosocomial infections, as K. pneumoniae show broad-spectrum...
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Screening Antibacterial Photodynamic Effect of Monascus Red Yeast Rice (Hong-Qu) and Mycelium Extracts
The fungus Monascus is a well-known source of secondary metabolites with interesting pharmaceutical and nutraceutical applications. In particular, Monascus...
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Therapeutic Potential of Fungal Endophyte-Derived Bioactive Compound in Protozoan Diseases
Endophytes are a group of microbes residing mutually within the tissues of their host plant without causing any overt symptoms. Secondary metabolites... -
Mycotoxins: Structure, Biosynthesis, Health Effects, and Their Biological Detoxification
Mycotoxins are a group of low molecular weight secondary metabolites that can lead to toxic reactions in humans and animals. These mycotoxins of... -
Biological monitoring for ochratoxin A and citrinin and their metabolites in urine samples of infants and children in Bangladesh
Ochratoxin A (OTA) and citrinin (CIT) are nephrotoxic mycotoxins, found in various foodstuffs and in animal feed, and may cause adverse effects on...
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Identification of the high-yield monacolin K strain from Monascus spp. and its submerged fermentation using different medicinal plants
BackgroundMedical plants confer various benefits to human health and their bioconversion through microbial fermentation can increase efficacy, reduce...
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Antimicrobial and Cytotoxic Secondary Metabolites from a Marine-Derived Fungus Penicillium Citrinum VM6
Investigation of an antimicrobial and cytotoxic ethyl acetate extract prepared from solid fermentation of the marine-derived fungus Penicillium...
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Hazard characterisation for significant mycotoxins in food
This review updates the current status of activities related to hazard characterisation for mycotoxins, with special reference to regulatory work...
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Multiple mycotoxins associated with maize (Zea mays L.) grains harvested from subsistence farmers’ fields in southwestern Ethiopia
Fifty-four maize grain samples freshly harvested from subsistence farmers’ fields in southwestern Ethiopia were analyzed for multiple mycotoxins...