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Developmental validation of a high-resolution panel genoty** 639 Y-chromosome SNP and InDel markers and its evolutionary features in Chinese populations
Uniparental-inherited haploid genetic marker of YÂchromosome single nucleotide polymorphisms (Y-SNP) have the power to provide a deep understanding...
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Genome-wide DNA methylation landscape of four Chinese populations and epigenetic variation linked to Tibetan high-altitude adaptation
DNA methylation (DNAm) is one of the major epigenetic mechanisms in humans and is important in diverse cellular processes. The variation of DNAm in...
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Genetic architecture and insecticide resistance in Chinese populations of Spodoptera frugiperda
The fall armyworm (FAW), Spodoptera frugiperda invaded China in December 2018 and has since spread quickly countrywide. Two sympatric biotype strains...
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A variant rs6214 within IGF-1 confers risk for ulcerative colitis in Chinese Han populations
Insulin growth factor-1 (IGF-1) has been found to correlate with various diseases such as cancer and cardiovascular diseases including ulcerative...
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Conservation genomics of the critically endangered Chinese pangolin
The Chinese pangolin ( Manis pentadactyla , MP) has been extensively exploited and is now on the brink of extinction, but its population structure,...
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Managing genomic diversity in conservation programs of Chinese domestic chickens
BackgroundEffective conservation and utilization of farm animals are fundamental for realizing sustainable increases in food production. In situ and...
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Associations of Chinese visceral adiposity index and new-onset stroke in middle-aged and older Chinese adults: an observational study
BackgroundStroke represents the second most prevalent contributor to global mortality. The Chinese Visceral Adiposity Index (CVAI) serves as an...
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Characterizing identity by descent segments in Chinese interpopulation unrelated individual pairs
Identity by descent (IBD) segments, uninterrupted DNA segments derived from the same ancestral chromosomes, are widely used as indicators of...
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The genomic history of southwestern Chinese populations demonstrated massive population migration and admixture among proto-Hmong–Mien speakers and incoming migrants
Southwest China was the crossroad for the initial settler people of East Asia, which shows the highest diversity in languages and genetics. This...
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Differentiated adaptative genetic architecture and language-related demographical history in South China inferred from 619 genomes from 56 populations
BackgroundThe underrepresentation of human genomic resources from Southern Chinese populations limited their health equality in the precision...
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A genome-wide association study of Chinese and English language phenotypes in Hong Kong Chinese children
Dyslexia and developmental language disorders are important learning difficulties. However, their genetic basis remains poorly understood, and most...
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Forkhead box P3 gene polymorphisms predispose to type 2 diabetes and diabetic nephropathy in the Han Chinese populations: a genetic-association and gender-based evaluation study
BackgroundFunctional mutations or polymorphisms affecting forkhead box P3 ( FOXP3) can lead to their abnormal FOXP3 gene expression and/or defective...
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Genomic formation of Tibeto-Burman speaking populations in Guizhou, Southwest China
Sino-Tibetan is the most prominent language family in East Asia. Previous genetic studies mainly focused on the Tibetan and Han Chinese populations....
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Differentiated genomic footprints suggest isolation and long-distance migration of Hmong-Mien populations
BackgroundThe underrepresentation of Hmong-Mien (HM) people in Asian genomic studies has hindered our comprehensive understanding of the full...
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Genetic diversity, genetic structure, and germplasm source of Chinese pine in North China
Chinese pine ( Pinus tabuliformis Carr.) is an important ecological and timber coniferous species endemic to China. In northern China, there are vast...
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Seed traits of reintroduced invasive populations of Triadica sebifera show few differences in comparison with those of native populations
Successful germination and establishment of invasive plants is a key early step during their invasion, which influences their invasive potential....
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Genetic influences on alcohol flushing in East Asian populations
BackgroundAlthough it is known that variation in the aldehyde dehydrogenase 2 ( ALDH2 ) gene family influences the East Asian alcohol flushing...
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Whole-genome resequencing of Chinese indigenous sheep provides insight into the genetic basis underlying climate adaptation
BackgroundChinese indigenous sheep are valuable resources with unique features and characteristics. They are distributed across regions with...
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Ancestral Information Analysis of Chinese Korean Ethnic Group via a Novel Multiplex DIP System
Deletion/insertion polymorphism (DIP) is one of the more promising genetic markers in the field of forensic genetics for personal identification and...
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Contrasting habitat use and conservation status of Chinese-wintering and other Eurasian Greater White-fronted Goose (Anser albifrons) populations
BackgroundGPS/GSM tracking data were used to contrast use of (i) habitats and (ii) protected areas between three Arctic-nesting Greater White-fronted...
