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Concept of Chimeric Organisms Such as Human/Non-Human Chimera (HNH-Chimera)
As an another direction in the xenotransplantation, chimeric organisms are recently represented in the regenerative medicine using the stem cells...
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Production of antiviral “OP7 chimera” defective interfering particles free of infectious virus
AbstractDefective interfering particles (DIPs) of influenza A virus (IAV) are suggested for use as broad-spectrum antivirals. We discovered a new...
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An oncolytic virus–T cell chimera for cancer immunotherapy
The efficacy of oncolytic adenoviruses (OAs) for cancer therapy has been limited by insufficient delivery to tumors after systemic injection and the...
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Management of Chimera and In Vitro Mutagenesis
Chimera may develop through spontaneous mutation or through treatment with physical and/or chemical mutagens. Management of chimera is very important...
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ChiMera: an easy to use pipeline for bacterial genome based metabolic network reconstruction, evaluation and visualization
BackgroundGenome-scale metabolic reconstruction tools have been developed in the last decades. They have helped to reconstruct eukaryotic and...
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Generation of allogenic chimera carrying mutations in PDX1 and TP53 genes via phytohemagglutinin-mediated blastomere aggregation in pigs
The generation of genetically engineered pig models that develop pancreas-specific tumors has the potential to advance studies and our understanding...
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Ubiquitin recruiting chimera: more than just a PROTAC
Ubiquitinylation of protein substrates results in various but distinct biological consequences, among which ubiquitin-mediated degradation is most...
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Insights into the C-terminal domain of apolipoprotein E from chimera studies with apolipophorin III
Apolipoprotein E3 (apoE) is a critical cholesterol transport protein in humans and is composed of two domains: a well characterized N-terminal (NT)...
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Somatic Embryogenesis and Temporary Immersion for Mass Propagation of Chimera-Free Mutant Arabica Coffee Plantlets
Coffee is one of the most valuable cash crops providing employment for millions of people worldwide. Arabica coffee is widely grown in Latin America...
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Controlling the Chimera Form in the Leaky Integrate-and-Fire Model
We study the influence of broken connectivity and frequency disorder in systems of coupled neuronal oscillators. Under nonlocal coupling, systems of...
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Molecular Dynamics Simulations of Channelrhodopsin Chimera, C1C2
Molecular dynamics (MD) simulations have been successfully used for modeling dynamic behavior of biologically relevant systems, such as ion channels...
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Computing Potential of the Mean Force Profiles for Ion Permeation Through Channelrhodopsin Chimera, C1C2
Umbrella sampling, coupled with a weighted histogram analysis method (US-WHAM), can be used to construct potentials of mean force (PMFs) for studying...
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Nuclear DNA content as an indicator of inflorescence colour stability of in vitro propagated solid and chimera mutants of chrysanthemum
In chrysanthemum, breeders seek for desirable characteristics of the inflorescence, which can first be established once the plant is mature. The...
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Alvis: a tool for contig and read ALignment VISualisation and chimera detection
BackgroundThe analysis of long reads or the assessment of assembly or target capture data often necessitates running alignments against reference...
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Adventitious Bud Technique
To avoid chimera formation there was search to find out plants which may originate from one or a few vegetative daughter cells or to standardize...
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MIR396-GRF/GIF enhances in planta shoot regeneration of Dendrobium catenatum
Recent studies on co-transformation of the growth regulator, TaGRF4-GIF1 chimera ( Growth Regulating Factor 4-GRF Interacting Factor 1 ), in cultivated...
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Chimeras in Merlot grapevine revealed by phased assembly
Chimerism is the phenomenon when several genotypes coexist in a single individual. Used to understand plant ontogenesis they also have been valorised...
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Dppa3 Improves the Germline Competence of Pluripotent Stem Cells
BackgroundChimera formation and germline competence are critical features of mouse pluripotent stem cells (PSCs). However, the factors that...
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Enhancement of zebrafish sperm production via a large body-sized surrogate with germ cell transplantation
Zebrafish ( Danio rerio ) is a commonly-used vertebrate model species for many research areas. However, its low milt volume limits effective...
