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Metagenomic Next-Generation Sequencing Contributes to the Early Diagnosis of Mixed Infections in Central Nervous System
Central nervous system (CNS) infections represent a challenge due to the complexities associated with their diagnosis and treatment, resulting in a...
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Herpesvirus Infections of the Central Nervous System
Double-stranded DNA herpesviruses are capable of establishing latency and reactivation. They are subdivided into eight human herpesviruses (HHVs):...
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Mold Infections of the Central Nervous System
Filamentous fungi are often identified as deadly human pathogens. They can cause invasive diseases in immunocompromised hosts, especially in those...
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Etiology and Epidemiology of Central Nervous System Infections
Infections of the central nervous system (CNS) are of utmost importance because of the various pathogens, emergence and re-emergence of new...
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Immune Responses in Infections of the Central Nervous System
The neurological invasion of pathogens into the central nervous system (CNS) causes inflammatory host–cell interactions, which inexplicably control...
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Viral and Fungal Infections of the Central Nervous System: A Microbiological Perspective
This book covers topics related to viral and fungal infections of the central nervous system (CNS), with a multidisciplinary reach, discussing...
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Natural killer cells in the central nervous system
Natural killer (NK) cells are essential components of the innate lymphoid cell family that work as both cytotoxic effectors and immune regulators....
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Role of NLRP3 inflammasome in central nervous system diseases
The central nervous system (CNS) is the most delicate system in human body, with the most complex structure and function. It is vulnerable to trauma,...
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The regulatory role of lipophagy in central nervous system diseases
Lipid droplets (LDs) are the organelles for storing neutral lipids, which are broken down when energy is insufficient. It has been suggested that...
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Advanced Microbiological Diagnostic Techniques in Viral Infections of the Central Nervous System
Conventional diagnosis of viral infections includes culture, antigen detection, serology and nucleic acid detection but with time, new techniques are...
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Common immunopathogenesis of central nervous system diseases: the protein-homeostasis-system hypothesis
There are hundreds of central nervous system (CNS) diseases, but there are few diseases for which the etiology or pathogenesis is understood as well...
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Advanced Microbiological Diagnostic Techniques in Fungal Infections of the Central Nervous System
Conventional diagnostic approaches, for example, culture and histology, which are believed as gold standards, have a low detection rate, emphasising...
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Cryptococcosis of the Central Nervous System
Cryptococcosis is the most common opportunistic fungal infection of the central nervous system caused by the genus Cryptococcus, a basidiomycete...
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Shiga Toxin and Its Effect on the Central Nervous System
Shiga toxin (Stx)Shiga toxin (Stx)-producing Escherichia coli (STECShiga-toxin producing E. coli (STEC)) is Virulence Virulence factors responsible...
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Asymptomatic herpes simplex virus brain infection elicits cellular senescence phenotypes in the central nervous system of mice suffering multiple sclerosis-like disease
Experimental autoimmune encephalomyelitis (EAE) is a demyelinating disease affecting the central nervous system (CNS) in animals that parallels...
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Central nervous system as a target of novel coronavirus infections: Potential routes of entry and pathogenic mechanisms
Since the COVID-19 pandemic started in December 2019, there have been several reports of patients succumbing to neurological complications. Early...
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Treatment of Fusarium Infection of the Central Nervous System: A Review of Past Cases to Guide Therapy for the Ongoing 2023 Outbreak in the United States and Mexico
IntroductionFusariosis of the central nervous system (CNS) is extremely uncommon. Treatment and outcome data from previously published cases may...
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Unraveling the lymphatic system in the spinal cord meninges: a critical element in protecting the central nervous system
The lymphatic vasculature plays a crucial role in fluid clearance and immune responses in peripheral organs by connecting them to distal lymph nodes....
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Overview of Infective Syndromes of the Central Nervous System and Its Coverings: Decoding Chameleons and Mimics
Infections of the central nervous system (CNS), which include those of the brain’s cerebrum and cerebellum, spinal cord, optic nerves, and the...
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SARS-CoV-2 interacts with renin-angiotensin system: impact on the central nervous system in elderly patients
SARS-CoV-2 is a recently identified coronavirus that causes the current pandemic disease known as COVID-19. SARS-CoV-2 uses angiotensin-converting...
