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Altering Escherichia coli envelope integrity by mimicking the lipoprotein RcsF
Escherichia coli cell envelope is crucial for stress sensing and signal transduction, mediated by numerous protein–protein interactions to enable...
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Impact of cell cycle on repair of ruptured nuclear envelope and sensitivity to nuclear envelope stress in glioblastoma
The nuclear envelope (NE) is often challenged by various stresses (known as “NE stress”), leading to its dysfunction. Accumulating evidence has...
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The interplay between cell wall integrity and cell cycle progression in plants
Plant cell walls are dynamic structures that play crucial roles in growth, development, and stress responses. Despite our growing understanding of...
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Lipid saturation controls nuclear envelope function
The nuclear envelope (NE) is a spherical double membrane with elastic properties. How NE shape and elasticity are regulated by lipid chemistry is...
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Cell Envelope Stress Response in Pseudomonas aeruginosa
Bacteria sense their environment via the cell envelope, which in Gram-negative bacteria comprises the outer membrane, the periplasmic space, and the...
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Novel role of PE_PGRS47 in the alteration of mycobacterial cell wall integrity and drug resistance
The proline-glutamic acid and proline-proline-glutamic acid (PE/PPE) family of proteins is widespread in pathogenic mycobacteria and plays different...
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Nesprin proteins: bridging nuclear envelope dynamics to muscular dysfunction
This review presents a comprehensive exploration of the pivotal role played by the Linker of Nucleoskeleton and Cytoskeleton (LINC) complex, with a...
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Purification of Chloroplast Envelope, Thylakoids, and Stroma from Angiosperm Leaves
Plant cell chloroplasts are bounded by a two-membrane envelope. Their photosynthetic function is based on the development of an operational large...
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Repurposing of therapeutic antibodies against dengue virus envelope protein receptor binding domain
Dengue virus (DENV) is the leading cause of numerous deaths every year due to its high infectivity. In this study we have tried to target the DENV...
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Super-resolution imaging of T lymphocyte activation reveals chromatin decondensation and disrupted nuclear envelope
T lymphocyte activation plays a pivotal role in adaptive immune response and alters the spatial organization of nuclear architecture that...
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Envelope-Stress Sensing Mechanism of Rcs and Cpx Signaling Pathways in Gram-Negative Bacteria
The global public health burden of bacterial antimicrobial resistance (AMR) is intensified by Gram-negative bacteria, which have an additional...
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Bacterial Envelope Fractionation
Numerous bioinformatics tools allow predicting the localization of membrane proteins in the outer or inner membrane of Escherichia coli with high...
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Repurposing of drugs targeting heparan sulphate binding site of dengue virus envelope protein: an in silico competitive binding study
Dengue virus, an arbovirus, leads to millions of infections every year ultimately leading to a high rate of mortality. Highly effective and specific...
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Atypical cyclic di-AMP signaling is essential for Porphyromonas gingivalis growth and regulation of cell envelope homeostasis and virulence
Microbial pathogens employ signaling systems through cyclic (di-) nucleotide monophosphates serving as second messengers to increase fitness during...
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An ESCRT grommet cooperates with a diffusion barrier to maintain nuclear integrity
The molecular mechanisms by which the endosomal sorting complexes required for transport (ESCRT) proteins contribute to the integrity of the nuclear...
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In Vivo Site-Directed and Time-Resolved Photocrosslinking of Envelope Proteins
In vivo site-directed photocrosslinking provides a means to probe the vicinity of proteins in their native cellular environment. Because this method...
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SWO1 modulates cell wall integrity under salt stress by interacting with importin ɑ in Arabidopsis
Maintenance of cell wall integrity is of great importance not only for plant growth and development, but also for the adaptation of plants to adverse...
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Meta-analysis towards FSHD reveals misregulation of neuromuscular junction, nuclear envelope, and spliceosome
Facioscapulohumeral muscular dystrophy (FSHD) is one of the most common autosomal dominant muscle disorders, yet no cure or amelioration exists. The...
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Gram-negative bacteria resist antimicrobial agents by a DzrR-mediated envelope stress response
BackgroundEnvelope stress responses (ESRs) are critical for adaptive resistance of Gram-negative bacteria to envelope-targeting antimicrobial agents....
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p53 regulates expression of nuclear envelope components in cancer cells
Nuclear organisation and architecture are essential for the maintenance of genomic integrity as well as for the epigenetic regulations and gene...
