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Archeological wood conservation with selected organosilicon compounds studied by XFM and nanoindentation
Waterlogged wood conservation is a complex and challenging task. Detailed knowledge about the interactions between the applied chemicals and wood is...
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Pore confinement enhances but surface adhesion reduces bacterial cell-to-cell conjugation
As the habitats of bacteria, soil pore network and surface properties control the distribution, adhesion, and motility of bacteria in soils. These...
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FKBP10 promotes clear cell renal cell carcinoma progression and regulates sensitivity to the HIF2α blockade by facilitating LDHA phosphorylation
Renal cell carcinoma (RCC) is one of the three major malignant tumors of the urinary system and originates from proximal tubular epithelial cells....
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Conservation of model degraded pine wood with selected organosilicons studied by XFM and nanoindentation
Previous research found that some organosilicon treatments proved effective in stabilizing waterlogged wood dimensions during drying. The present...
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Marine Polysaccharides Carrageenans Enhance Eryptosis and Alter Lipid Order of Cell Membranes in Erythrocytes
Aim In the current study, hemocompatibility of three major commercially available types of carrageenans (ι, κ and λ) was investigated focusing on...
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Arsenic trioxide augments immunogenic cell death and induces cGAS-STING-IFN pathway activation in hepatocellular carcinoma
The treatment of hepatocellular carcinoma (HCC) is particularly challenging due to the inherent tumoral heterogeneity and easy resistance towards...
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Genetic recording of in vivo cell proliferation by ProTracer
The ability to experimentally measure cell proliferation is the basis for understanding the sources of cells that drive organ development, tissue...
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Single-cell RNA-seq integrated with multi-omics reveals SERPINE2 as a target for metastasis in advanced renal cell carcinoma
Tumor growth, metastasis and therapeutic response are believed to be regulated by the tumor and its microenvironment (TME) in advanced renal cell...
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CHST2-mediated sulfation of MECA79 antigens is critical for breast cancer cell migration and metastasis
Snail is a denoted transcriptional repressor that plays key roles in epithelial-mesenchymal transition (EMT) and metastasis. Lately, a plethora of...
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Enzyme-controlled, nutritive hydrogel for mesenchymal stromal cell survival and paracrine functions
Culture-adapted human mesenchymal stromal cells (hMSCs) are appealing candidates for regenerative medicine applications. However, these cells...
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Cell-intrinsic and microenvironmental determinants of metastatic colonization
Cancer metastasis is a biologically complex process that remains a major challenge in the oncology clinic, accounting for nearly all of the mortality...
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Fractal dimension of wood cell wall pores from pore size distribution: insights from nitrogen gas adsorption analyzer
Understanding wood cell wall pore geometry and distribution is the basis for studying its macroscopic properties. This research investigated the pore...
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Biogeographic implication of temperature-induced plant cell wall lignification
More than 200 years after von Humboldt’s pioneering work on the treeline, our understanding of the cold distribution limit of upright plant growth is...
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YAP is required for prostate development, regeneration, and prostate stem cell function
Prostate development and regeneration depend on prostate stem cell function, the delicate balance of stem cell self-renewal and differentiation....
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Gingival-derived mesenchymal stem cell therapy regenerated the radiated salivary glands: functional and histological evidence in murine model
BackgroundRadiotherapy in head and neck cancer management causes degeneration of the salivary glands (SG). This study was designed to determine the...
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Towards Stem/Progenitor Cell-Based Therapies for Retinal Degeneration
Retinal degeneration (RD) is a leading cause of blindness worldwide and includes conditions such as retinitis pigmentosa (RP), age-related macular...
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CD83 expression characterizes precursor exhausted T cell population
T cell exhaustion is a main obstacle against effective cancer immunotherapy. Exhausted T cells include a subpopulation that maintains proliferative...
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A new thinking: deciphering the aberrance and clinical implication of copper-death signatures in clear cell renal cell carcinoma
RationaleRecent research has indicated that cuprotosis, or copper induced cell death, is a novel type of cell death that could be utilized as a new...
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Methods to Investigate Cell Polarity of Inner Ear
Hair cells in cochlea and vestibular organs depend on the coordinated cell polarity to perform the normal auditory or balance function. The mouse...
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Cell-based passive immunization for protection against SARS-CoV-2 infection
BackgroundImmunologically impaired individuals respond poorly to vaccines, highlighting the need for additional strategies to protect these...
