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cAMP signaling factors regulate carbon catabolite repression of hemicellulase genes in Aspergillus nidulans
Carbon catabolite repression (CCR) enables preferential utilization of easily metabolizable carbon sources, implying the presence of mechanisms to...
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Selection of Carbon Sources by Rhizobacteria – A Muster of Signalling Factors Governing Carbon Catabolite Repression
Rhizosphere is a dense dynamic area of soil around the roots harbouring plant-beneficial bacteria thriving on the nutrients obtained from plants.... -
Functional characterization and comparative analysis of gene repression-mediating domains interacting with yeast pleiotropic corepressors Sin3, Cyc8 and Tup1
Transcriptional corepressors Sin3, Cyc8 and Tup1 are important for downregulation of gene expression by recruiting various histone deacetylases once...
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Loss of function of the carbon catabolite repressor CreA leads to low but inducer‐independent expression from the feruloyl esterase B promoter in Aspergillus niger
ObjectiveWith the aim to decipher the mechanisms involved in the transcriptional regulation of feruloyl esterase encoded by faeB , a genetic screen...
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The deubiquitinating enzyme MoUbp8 is required for infection-related development, pathogenicity, and carbon catabolite repression in Magnaporthe oryzae
Deubiquitination is an essential regulatory step in the Ub-dependent pathway. Deubiquitinating enzymes (DUBs) mediate the removal of ubiquitin...
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Crotonylation of key metabolic enzymes regulates carbon catabolite repression in Streptomyces roseosporus
Due to the plethora natural products made by Streptomyces , the regulation of its metabolism are of great interest, whereas there is a lack of...
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Pseudomonad reverse carbon catabolite repression, interspecies metabolite exchange, and consortial division of labor
Microorganisms acquire energy and nutrients from dynamic environments, where substrates vary in both type and abundance. The regulatory system...
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Poly(butylene adipate-co-terephthalate) biodegradation by Purpureocillium lilacinum strain BA1S
AbstractPoly(butylene adipate-co-terephthalate) (PBAT), a promising biodegradable aliphatic-aromatic copolyester material, can be applied as an...
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Catabolite responsive elements as a strategy for the control of heterologous gene expression in lactobacilli
AbstractGenes involved in the transport and catabolism of carbohydrates are usually controlled through the binding of the catabolite control protein...
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Sha** bacterial gene expression by physiological and proteome allocation constraints
Networks of molecular regulators are often the primary objects of focus in the study of gene regulation, with the machinery of protein synthesis...
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High-level production of industrially relevant oxidases by a two-stage fed-batch approach: overcoming catabolite repression in arabinose-inducible Escherichia coli systems
AbstractWith the growing interest in enzyme applications, there is an urgent demand for economic, affordable, and flexible enzyme production...
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Carbon catabolite repression: not only for glucose
Most organisms prefer to utilize glucose as a carbon source. Accordingly, the expression of genes involved in the catabolism of other carbon sources...
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Group B Streptococcus Cas9 variants provide insight into programmable gene repression and CRISPR-Cas transcriptional effects
Group B Streptococcus (GBS; S. agalactiae ) causes chorioamnionitis, neonatal sepsis, and can also cause disease in healthy or immunocompromised...
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Current models in bacterial hemicellulase-encoding gene regulation
AbstractThe discovery and characterization of bacterial carbohydrate-active enzymes is a fundamental component of biotechnology innovation,...
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The protein methyltransferase TrSAM inhibits cellulase gene expression by interacting with the negative regulator ACE1 in Trichoderma reesei
Protein methylation is a commonly posttranslational modification of transcriptional regulators to fine-tune protein function, however, whether this...
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Dietary fibre directs microbial tryptophan metabolism via metabolic interactions in the gut microbiota
Tryptophan is catabolized by gut microorganisms resulting in a wide range of metabolites implicated in both beneficial and adverse host effects. How...
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Single mutation makes Escherichia coli an insect mutualist
Microorganisms often live in symbiosis with their hosts, and some are considered mutualists, where all species involved benefit from the interaction....
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Rewiring the functional complexity between Crc, Hfq and sRNAs to regulate carbon catabolite repression in Pseudomonas
Pseudomonas species are the most versatile of all known bacteria for metabolic flexibility and the extent of host range from plants to humans that...
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Xylitol Production by Candida tropicalis from Sugarcane Bagasse and Straw: an Adaptive Approach to Improve Fermentative Performance
The toxicity of hemicellulosic hydrolysates is one of the main bottlenecks of the biotechnological production of xylitol, as inhibitors...
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Utilization of lignocellulosic hydrolysates for photomixotrophic chemical production in Synechococcus elongatus PCC 7942
To meet the need for environmentally friendly commodity chemicals, feedstocks for biological chemical production must be diversified. Lignocellulosic...