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Carnitine modulates antioxidative defense in ABI2 mutant under salt stress
Carnitine, a ubiquitous compound in living organisms, fulfills diverse roles in energy metabolism, stress resilience, and detoxification. Its...
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Association between plasma L-carnitine levels and mitochondrial DNA copy number
Mitochondria are key cytoplasmic organelles in eukaryotic cells that generate adenosine triphosphate (ATP) through the electron transport chain and...
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The efficacy of L-carnitine in patients with nonalcoholic steatohepatitis and concomitant obesity
BackgroundIn light of the high prevalence of nonalcoholic fatty liver disease and obesity, treatment options for nonalcoholic steatohepatitis are of...
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Drought stress mitigation by foliar application of L-carnitine and its effect on radish morphophysiology
Drought is the major abiotic stress limiting crop production worldwide, with drought events being expected to be harsher and more frequent due to the...
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Exogenous Carnitine Mitigates the Deleterious Effects of Mild-Water Stress on Arugula by Modulating Morphophysiological Responses
Water deficiency is a threat to food security and limits the yield of vegetables, including arugula ( Eruca sativa Mill.). Despite the increasing use...
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Embryonic exposure to acetyl-L-carnitine protects against valproic acid-induced cardiac malformation in zebrafish model
Worldwide, estimated counts of about 7.9 million children are born with serious birth defects. In addition to genetic factors, prenatal exposure to...
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Exogenous carnitine application enhances the growth of culantro (Eryngium foetidum) plants
Carnitine is an amino acid that is common to all living organisms and is involved in energy metabolism and stress tolerance in plants. In this...
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Dietary L-carnitine supplementation changes lipid metabolism and glucose utilization of Rhynchocypris lagowskii fed diets with different lipid sources
The widely available crop oil is an effective alternative to the increasingly scarce marine fish oil. However, simple alternative strategies have led...
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Changes of the liver metabolome following an intravenous lipopolysaccharide injection in Holstein cows supplemented with dietary carnitine
BackgroundCarnitine facilitates the flux of long-chain fatty acids for hepatic mitochondrial beta-oxidation, which acts to ameliorate the negative...
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Plasma linoelaidyl carnitine levels positively correlated with symptom improvement in olanzapine-treated first-episode drug-naïve schizophrenia
IntroductionOlanzapine (OLA) is one of the most commonly used second-generation antipsychotics for the treatment of schizophrenia. However, the...
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Role of carnitine in adaptation of Chromohalobacter salexigens DSM 3043 and its mutants to osmotic and temperature stress in defined medium
L-Carnitine is widespread in nature, but little information is available on its metabolism and physiological functions in moderate halophiles. In...
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Bacterial over-expression of functionally active human CT2 (SLC22A16) carnitine transporter
BackgroundEscherichia coli is a widely used tool for the over-expression of human proteins for studying structure and function. The toxicity of...
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Evaluation of the gene encoding carnitine transporter (OCTN2/SLC22A5) expression in human breast cancer and its association with clinicopathological characteristics
BackgroundFatty acid oxidation (FAO) is a major energy-generating process in the mitochondria and supports proliferation, growth, and survival of...
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Dietary L-carnitine and nucleotides synergistically enhance growth performance, feed utilization, and antioxidant capacity of largemouth bass (Micropterus salmoides) juvenile fed a high-fat diet
Dietary L-carnitine (LC) and nucleotides (NT) are additives used independently in fish feeds. However, whether they work antagonistically or...
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Carnitine palmitoyltransferase 1A promotes mitochondrial fission by enhancing MFF succinylation in ovarian cancer
Mitochondria are dynamic organelles that are important for cell growth and proliferation. Dysregulated mitochondrial dynamics are highly associated...
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High serum levels of l-carnitine and citric acid negatively correlated with alkaline phosphatase are detectable in Koreans before gastric cancer onset
IntroductionMonitoring metabolic biomarkers could be utilized as an effective tool for the early detection of gastric cancer (GC) risk.
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Beneficial impact of dietary methyl methionine sulfonium chloride and/or L-carnitine supplementation on growth performance, feed efficiency, and serum biochemical parameters in broiler chicken: role of IGF-1 and MSTN genes
The purpose of this study was to examine the effect of dietary supplementation with methyl methionine sulfonium chloride (MMSC), and L-carnitine...
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The effects of dietary L-carnitine supplementation in fish diet containing high corn gluten meal on immunity, lipid metabolism, and metabolomics in juvenile hybrid grouper (♀Epinephelus fuscoguttatus × ♂Epinephelus lanceolatus)
This study examined the effects of L-carnitine (LC) supplementation in corn gluten meal (CGM) diets for juvenile hybrid grouper on growth, immunity,...
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The microbial gbu gene cluster links cardiovascular disease risk associated with red meat consumption to microbiota l-carnitine catabolism
The heightened cardiovascular disease (CVD) risk observed among omnivores is thought to be linked, in part, to gut microbiota-dependent generation of...
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Suitable ratio of dietary L-carnitine and α-ketoglutarate improves growth and health performance in Nile tilapia, Oreochromis niloticus
L-carnitine (LC) and α-Ketoglutarate (AKG) are important growth promoters used in aquafeed. The study aimed to evaluate the incorporation of LC and...
