Search
Search Results
-
Digging into boring bryozoans: new characters and new species of Immergentiidae
Immergentia is an endolithic genus of ctenostome bryozoans and the sole member of the Immergentiidae. Etchings of their typical spindled-shaped and...
-
Mesenchymal Stem Cells for Cardiac Repair
Cardiovascular diseases (CVDs), particularly acute and chronic ischemic heart disease (IHD), are the primary cause of morbidity and mortality...
-
Mesenchymal Stem Cells for Cardiac Repair
Cardiovascular diseases (CVDs), particularly acute and chronic ischemic heart disease (IHD), are the primary cause of morbidity and mortality...
-
The Effect of Time of Cell Delivery on Post-MI Cardiac Regeneration: A Review of Preclinical and Clinical Studies
Despite the contemporary advancements in pharmacological and surgical treatment methods, the failing heart remains the primary cause of morbidity and...
-
Cardiovascular Stem Cell Applications in Experimental Animal Models
Stem cells are increasingly used in various species for differing diseases, most frequently experimentally. In addition, several animals are also...
-
Blood Flow Changes in the Rabbit Cranial and Caudal Venae Cavae during Postural Loads after Propranolol, Bisoprolol and Methyldopa Pretreatment
AbstractThe β 1,2 -adrenergic receptor blocker propranolol, β 1 -blocker bisoprolol, and central presynaptic α 2 -adrenergic receptor agonist methyldopa...
-
Bone Marrow and Wharton’s Jelly Mesenchymal Stromal Cells are Ineffective for Myocardial Repair in an Immunodeficient Rat Model of Chronic Ischemic Cardiomyopathy
BackgroundAlthough cell therapy provides benefits for outcomes of heart failure, the most optimal cell type to be used clinically remains unknown....
-
Utility of the burmese Python as a model for studying plasticity of extreme physiological systems
Non-traditional animal models present an opportunity to discover novel biology that has evolved to allow such animals to survive in extreme...
-
Human Myoblast Genome Therapy and the Regenerative Heart
Heart muscle degeneration leading to heart failure is one of the most debilitating and fatal conditions affecting mankind. Over the past 22 years,...
-
Rho-kinase inhibition reduces systolic blood pressure and forearm vascular resistance in healthy older adults: a double-blind, randomized, placebo-controlled pilot study
Rho-kinase has been implicated in the development of hypertension in preclinical studies and may contribute to age-related blood pressure elevation....
-
Preclinical study of human umbilical cord mesenchymal stem cell sheets for the recovery of ischemic heart tissue
BackgroundHuman umbilical cord mesenchymal stem cells (hUC-MSCs) have been widely used due to their multipotency, a broad range of sources, painless...
-
Effect of T- and L-Type Calcium Channel Blockers on Pulmonary Microhemodynamics in a Rabbit Model of Pulmonary Thromboembolism
AbstractChanges in the pulmonary microhemodynamics in response to ethosuximide, mibefradil, nifedipine, and chloroquine were studied under conditions...
-
Arginase: shedding light on the mechanisms and opportunities in cardiovascular diseases
Arginase, a binuclear manganese metalloenzyme in the urea, catalyzes the hydrolysis of L-arginine to urea and L-ornithine. Both isoforms, arginase 1...
-
Role of the Superoxide Radical in Regulation of Coronary Vascular Kv Channels in Posttraumatic Stress Disorder
AbstractThe aim of this work was to study the contribution of the superoxide radical (О2 ●– ) to the mechanisms underlying the dysfunction of coronary...
-
Single-nucleus transcriptomics of epicardial adipose tissue from female pigs reveals effects of exercise training on resident innate and adaptive immune cells
BackgroundCoronary artery disease (CAD) is a leading cause of death in women. Epicardial adipose tissue (EAT) secretes cytokines to modulate coronary...
-
Effect of Doxorubicin on the Reactivity of Rat Mesenteric Arteries
AbstractDoxorubicin is widely used as an antitumor drug, but it has a negative effect on the cardiovascular system. While special attention has...
-
Current and future strategies for targeting the endothelin pathway in cardiovascular disease
The first endothelin (ET)-1 receptor antagonist was approved for clinical use over 20 years ago, but to date this class of compounds has been limited...
-
Boring bryozoans: an investigation into the endolithic bryozoan family Penetrantiidae
An endolithic lifestyle in mineralized substrates has evolved multiple times in various phyla including Bryozoa. The family Penetrantiidae includes...
-
MSC-Derived Exosomes: Advances in Cell-Free Therapy
Mesenchymal stem cells (MSCs)Mesenchymal stem cells (MSCs) are a rich source of bioactive molecules, which they secrete as a part of their paracrine...
-
MSC-Derived Exosomes: Advances in Cell-Free Therapy
Mesenchymal stem cells (MSCs)Mesenchymal stem cells (MSCs) are a rich source of bioactive molecules, which they secrete as a part of their paracrine...