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Synergid cell calcium oscillations refine understanding of FERONIA/LORELEI signaling during interspecific hybridization
Key messagePollen tubes from closely related species and mutants lacking pollen tube MYB transcription factors are able to initiate FER/LRE-dependent...
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Comparative Investigation of the Mechanisms of Calcium Response in Human and Murine Spermatozoa
Abstract āCalcium signaling is a principal method of signal transduction in cells of non-excitable tissues. In both mouse and human sperm, it can be...
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Electromagnetic fields regulate calcium-mediated cell fate of stem cells: osteogenesis, chondrogenesis and apoptosis
Electromagnetic fields (EMF) are increasing in popularity as a safe and non-invasive therapy. On the one hand, it is widely acknowledged that EMF can...
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Generation of āsemi-guidedā cortical organoids with complex neural oscillations
Temporal development of neural electrophysiology follows genetic programming, similar to cellular maturation and organization during development. The...
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Computational modeling of AMPK and mTOR crosstalk in glutamatergic synapse calcium signaling
Neuronal energy consumption is vital for information processing and memory formation in synapses. The brain consists of just 2% of the human bodyās...
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Cytosolic Calcium Distribution and Thrombin Receptor Activation
Since, receptor plays significant role in calcium signalling and to understand the mechanism of signalling in detail; an essential component is the... -
Do oscillations in pancreatic islets require pacemaker cells?
The pancreatic islets of Langerhans are biomedically important because they are home to the beta cells that secrete insulin and are hence important...
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Active oscillations in microscale navigation
Living organisms routinely navigate their surroundings in search of better conditions, more food, or to avoid predators. Typically, animals do so by...
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Reduced mitochondrial calcium uptake in macrophages is a major driver of inflammaging
Mitochondrial dysfunction is linked to age-associated inflammation or inflammaging, but underlying mechanisms are not understood. Analyses of 700...
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Calcium in the Life Cycle of Legume Root Nodules
The present review highlights both the fundamental questions of calcium localization, compartmentation, and its participation in symbiosome signaling...
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Calcium imaging: a technique to monitor calcium dynamics in biological systems
Calcium ion (Ca 2+ ) is a multifaceted signaling molecule that acts as an important second messenger. During the course of evolution, plants and...
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Influence of microgravity on spontaneous calcium activity of primary hippocampal neurons grown in microfluidic chips
The influence of variations of gravity, either hypergravity or microgravity, on the brain of astronauts is a major concern for long journeys in...
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Electromagnetic-Induced Calcium Signal with Network Coding for Molecular Communications
Molecular communication (MC) has become a new communication technology between nano-scale devices due to its biocompatibility and low energy... -
TFEB activation triggers pexophagy for functional adaptation during oxidative stress under calcium deficient-conditions
BackgroundCalcium is a ubiquitous intracellular messenger that regulates the expression of various genes involved in cell proliferation,...
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Calcium and Phosphate Ion Uptake, Distribution, and Homeostasis in Cells of Vertebrate Mineralized Tissues
The chapter considers mechanisms by which cells regulate calcium and phosphate ion homeostasis with respect to the induction of extracellular... -
NOX4-derived ROS are neuroprotective by balancing intracellular calcium stores
Hyperexcitability is associated with neuronal dysfunction, cellular death, and consequently neurodegeneration. Redox disbalance can contribute to...
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Calcium signaling-mediated transcriptional reprogramming during abiotic stress response in plants
Calcium (Ca 2+ ) is a second messenger in plants growth and development, as well as in stress responses. The transient elevation in cytosolic Ca 2+ ...
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P-type calcium ATPases play important roles in biotic and abiotic stress signaling
Main conclusionKnowledge of Ca 2+ -ATPases is imperative for improving crop quality/ food security, highly threatened due to global warming. Ca 2+ -ATPas...
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Engineering of NEMO as calcium indicators with large dynamics and high sensitivity
Genetically encoded calcium indicators (GECIs) are indispensable tools for real-time monitoring of intracellular calcium signals and cellular...
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Rasal1 regulates calcium dependent neuronal maturation by modifying microtubule dynamics
BackgroundRasal1 is a Ras GTPase-activating protein which contains C2 domains necessary for dynamic membrane association following intracellular...