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Silica nanoparticles induce ovarian granulosa cell apoptosis via activation of the PERK-ATF4-CHOP-ERO1α pathway-mediated IP3R1-dependent calcium mobilization
Ambient particulate matters (PMs) have adverse effects in human and animal female reproductive health. Silica nanoparticles (SNPs), as a major...
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Fluorescence-coupled micropipette aspiration assay to examine calcium mobilization caused by red blood cell mechanosensing
Mechanical stimuli such as tension, compression, and shear stress play critical roles in the physiological functions of red blood cells (RBCs) and...
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Cytosolic Calcium Distribution and Thrombin Receptor Activation
Since, receptor plays significant role in calcium signalling and to understand the mechanism of signalling in detail; an essential component is the... -
FLIPR Calcium Mobilization Assays in GPCR Drug Discovery
Intracellular calcium mobilization can be measured using several methods varying in indicator dyes and devices used. In this chapter, we describe the... -
PKC-β modulates Ca2+ mobilization through Stim1 phosphorylation
BackgroundCalcium ions play a pivotal role in cell proliferation, differentiation, and migration. Under basal conditions, the calcium level is...
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Activating mutations in JAK2 and CALR differentially affect intracellular calcium flux in store operated calcium entry
BackgroundCalcium (Ca 2+ ) signaling regulates various vital cellular functions, including integrin activation and cell migration. Store-operated...
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Reserve mobilization and the role of primary metabolites during the germination and initial seedling growth of rubber tree genotypes
During seed germination until photoautotrophic establishment, the mobilization of seed-stored reserves represents the main source of carbon...
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Combined Application of Calcium-Magnesium Phosphate Fertilizer with Soluble Phosphorus Improves Maize Growth in a Calcareous Soil
This study aimed at revealing the mechanism of calcium-magnesium phosphate fertilizer (CMP) mobilization the mechanism of starter phosphorus (P)...
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Fruit-Stalk Supplementing Calcium and Partition Regulation of Fruit Calcium for Prevention of Bitter Pit of Bagged Apple
Conventional strategies for the calcium supplementation of apples, such as via direct spray application on the fruit or administering the supplement...
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Calcium Imaging of Non-adherent Cells
Live-cell imaging can reveal dynamic and multimodal cell signaling by monitoring calcium flux. Spatiotemporal changes in Ca2+ concentrations... -
Purinergic Signaling and Its Role in Mobilization of Bone Marrow Stem Cells
Mobilization or egress of stem cells from bone marrow (BM) into peripheral blood (PB) is an evolutionary preserved and important mechanism in an... -
Phosphate Mobilization by Culturable Fungi and Their Capacity to Increase Soil P Availability and Promote Barley Growth
Large-scale screening of 848 culturable soil and endophytic filamentous fungi and yeasts for the ability to mobilize inorganic and organic P...
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Drosophila Atlastin regulates synaptic vesicle mobilization independent of bone morphogenetic protein signaling
BackgroundThe endoplasmic reticulum (ER) contacts endosomes in all parts of a motor neuron, including the axon and presynaptic terminal, to move...
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Silicon improves seed germination and seedling growth and alleviates salt stress in Medicago sativa L. by regulating seed reserve mobilization and antioxidant system defense
Exogenous application of silicon (Si) provides benefits to various plant species, including alfalfa. However, knowledge about the effects of Si on...
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Review of Local Cellular and Molecular Processes of Bone Tissue Regeneration Induced by Calcium Phosphate Materials
AbstractOne of the leading causes of hospitalization, disability, and mortality in 50% of women and 20% of men in age group over 50 years of age is...
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Lipolysis: cellular mechanisms for lipid mobilization from fat stores
The perception that intracellular lipolysis is a straightforward process that releases fatty acids from fat stores in adipose tissue to generate...
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Calcium dynamics during the growth of Agaricus bisporus: implications for mushroom development and nutrition
BackgroundAgaricus bisporus ( A. bisporus ) is highly valued for its nutritional benefits and delicious taste, making it one of the most widely...
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Iron Metabolism, Calcium, Magnesium and Trace Elements: A Review
Iron (Fe) is fundamental to life on earth. In the human body, it is both essential and harmful if above threshold. A similar balance applies to other...
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Calcium Homeostasis in Spermatozoa: Regulatory Mechanisms and Biological Significance
Abstract —Calcium is one of the most important elements for intracellular signaling. Its role is so big and complex that we can distinguish various...
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Trafficking of Neuronal Calcium Channels
Neuronal voltage-gated calcium channels (VGCCs) serve a wide range of complex yet critical physiological functions by converting electrical signals...