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The Bovine Pangenome Consortium: democratizing production and accessibility of genome assemblies for global cattle breeds and other bovine species
The Bovine Pangenome Consortium (BPC) is an international collaboration dedicated to the assembly of cattle genomes to develop a more complete...
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Genome sequencing and comparative genomic analysis of bovine mastitis-associated Staphylococcus aureus strains from India
BackgroundBovine mastitis accounts for significant economic losses to the dairy industry worldwide. Staphylococcus aureus is the most common...
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High-resolution structural variants catalogue in a large-scale whole genome sequenced bovine family cohort data
BackgroundStructural variants (SVs) are chromosomal segments that differ between genomes, such as deletions, duplications, insertions, inversions and...
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Genomic evolution of bovine viral diarrhea virus based on complete genome and individual gene analyses
Bovine viral diarrhea virus (BVDV) genome consists of a single-stranded, positive-sense RNA with high genetic diversity. In the last years,...
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Whole genome characterization and evolutionary analysis of bovine ephemeral fever virus isolated in Iran
Bovine ephemeral fever virus (BEFV) is an economically important arthropod-borne virus of cattle and water buffaloes which is enzootic in Africa,...
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Unravelling transmission ratio distortion across the bovine genome: identification of candidate regions for reproduction defects
BackgroundBiological mechanisms affecting gametogenesis, embryo development and postnatal viability have the potential to alter Mendelian inheritance...
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Genome-Based Characterization of Multidrug-Resistant Escherichia coli Isolated from Clinical Bovine Mastitis
Mastitis occurrence in dairy cows is a broad topic that involves several sectors, from antimicrobial resistance and virulence of strains to economic...
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Genome Editing of Rat
Many genetically engineered rat strains have been produced by the development of genome editing technology, although it used to be technical...
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Genome-wide identification of enhancers and transcription factors regulating the myogenic differentiation of bovine satellite cells
BackgroundSatellite cells are the myogenic precursor cells in adult skeletal muscle. The objective of this study was to identify enhancers and...
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Genome Editing of Pig
Pigs have anatomical and physiological characteristics similar to humans; therefore, genetically modified pigs have the potential to become a...
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Single-cell profiling reveals transcriptome dynamics during bovine oocyte growth
BackgroundMammalian follicle development is characterized by extensive changes in morphology, endocrine responsiveness, and function, providing the...
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Bovine host genome acts on rumen microbiome function linked to methane emissions
Our study provides substantial evidence that the host genome affects the comprehensive function of the microbiome in the rumen of bovines. Of...
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The intronic branch point sequence is under strong evolutionary constraint in the bovine and human genome
The branch point sequence is a cis-acting intronic motif required for mRNA splicing. Despite their functional importance, branch point sequences are...
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Establishment of a cloning-free CRISPR/Cas9 protocol to generate large deletions in the bovine MDBK cell line
The CRISPR/Cas9 technique applied to modify the cattle genome has value in increasing animal health and welfare. Here, we established a simple, fast,...
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Chromatin profiling reveals TFAP4 as a critical transcriptional regulator of bovine satellite cell differentiation
BackgroundSatellite cells are myogenic precursor cells in adult skeletal muscle and play a crucial role in skeletal muscle regeneration, maintenance,...
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Genome sequencing and de novo and reference-based genome assemblies of Bos indicus breeds
BackgroundIndian cattle breeds ( Bos indicus ) are known for their remarkable adaptability to hot and humid climates, higher nutritious quality of...
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Prevalence of bovine herpes virus-1 among reproductive disorders in cattle and buffaloes in Punjab region of India
Bovine Herpes Virus (BHV-1) is a virus prevalent among cattle and buffaloes which accounts for considerable reproductive failures. This study was...
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Integrated analysis of microRNA and messenger RNA expression profiles reveals functional microRNA in infectious bovine rhinotracheitis virus-induced mitochondrial damage in Madin-Darby bovine kidney cells
BackgroundStudies have confirmed that Infectious bovine rhinotracheitis virus (IBRV) infection induces mitochondrial damage. MicroRNAs (miRNAs) are a...
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Genome Editing Mediated by Primordial Germ Cell in Chicken
Genome editing technology has facilitated the studies on exploring specific gene functions in diverse living organisms. The technology has also...
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Genome-wide post-transcriptional regulation of bovine mammary gland response to Streptococcus uberis
MicroRNAs (miRNAs) as post-transcriptionally regulators of gene expression have been shown to be critical regulators to fine-tuning immune responses,...
