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Association of PFN1 Gene Polymorphisms with Bone Mineral Density, Bone Turnover Markers, and Osteoporotic Fractures in Chinese Population
Recent studies have discovered an association between the PFN1 gene and Paget’s disease. However, it is currently unknown whether the PFN1 gene is...
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Bone Turnover Markers and Wnt Signaling Modulators in Early Complex Regional Pain Syndrome. A Pre-specified Observational Study
To explore serum levels of some bone turnover markers and the involvement of the Wnt signaling in CRPS-1. Query ID="Q1" Text="Please check and...
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Laboratory Markers of Platelet Production and Turnover
AbstractPlatelets are formed from bone marrow megakaryocytes, circulate in blood for 7-10 days, and then are destroyed in the spleen and/or liver....
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Bone Turnover Markers in Children: From Laboratory Challenges to Clinical Interpretation
Bone turnover markers (BTMs) have been developed many years ago to study, in combination with imaging techniques, bone remodeling in adults. In...
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Evaluation of Bone Turnover Markers in Patients with Acute and Chronic Leukemia
This study investigated different bone biomarkers (cross-linked carboxy-terminal telopeptide of type 1 collagen (CTX-1), pyridinoline (PYD),...
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The Effect of Effervescent and Buffered Alendronate Compared to Conventional Alendronate on Markers of Bone Turnover: A Randomized Non-inferiority Trial
Buffered and effervescent alendronate (ALN-EFF) increases gastric pH and is reported to decrease the risk of gastrointestinal side effects compared...
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Practical Considerations for the Clinical Application of Bone Turnover Markers in Osteoporosis
Bone turnover markers (BTMs) are released during the bone remodelling cycle and are measurable in blood or urine, reflecting bone remodelling rate....
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Determinants of Low Bone Turnover in Type 2 Diabetes-the Role of PTH
Determinants of low bone turnover in type 2 diabetes (T2DM) are poorly understood. To investigate the relationship between markers of bone turnover,...
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Evaluation of Bone Turnover Markers Such as Osteoprotegerin, Sclerostin and Dickkopf-1 in Subclinical Hyperthyroidism
In this study, it was aimed to assess effects of subclinical hyperthyroidism (SH) on bone metabolism using osteoprotegerin (OPG), sclerostin,...
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Bone Turnover Markers After Six Nights of Insufficient Sleep and Subsequent Recovery Sleep in Healthy Men
PurposeThe goal of this study was to determine the bone turnover marker (BTM) response to insufficient and subsequent recovery sleep, independent of...
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Clinical Prediction of High-Turnover Bone Disease After Kidney Transplantation
Bone histomorphometric analysis is the most accurate method for the evaluation of bone turnover, but non-invasive tools are also required. We studied...
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Bone Turnover Marker Profiling and Fracture Risk in Older Women: Fracture Risk from Age 75 to 90
PurposeA major challenge in osteoporosis is to identify individuals at high fracture risk. We investigated six bone turnover markers (BTMs) to...
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Genetic markers associated with bone composition in Rhode Island Red laying hens
BackgroundBone damage has welfare and economic impacts on modern commercial poultry and is known as one of the major challenges in the poultry...
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Exposure of Arsenic Associated with Cellular Turnover and Apoptosis Profile in the Bone Marrow of Mice Including Stem/Progenitor Population
Arsenic toxicity is a current global concern due to its devastating toxic effects on human health. Over several millions of people are exposed to...
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A Systematic Review of the Circadian Rhythm of Bone Markers in Blood
There exists a marked circadian variation for several bone markers (BM), which is influenced by endogenous as well as exogenous factors including...
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Bone Histomorphometry and 18F-Sodium Fluoride Positron Emission Tomography Imaging: Comparison Between only Bone Turnover-based and Unified TMV-based Classification of Renal Osteodystrophy
Bone biopsy is the gold standard for characterization of renal osteodystrophy (ROD). However, the classification of the subtypes of ROD based on...
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Bone Mineral Density During and After Lactation: A Comparison of African American and Caucasian Women
During lactation, changes in maternal calcium metabolism are necessary to provide adequate calcium for newborn skeletal development. The calcium in...
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New Emerging Biomarkers for Bone Disease: Sclerostin and Dickkopf-1 (DKK1)
A healthy skeleton depends on a continuous renewal and maintenance of the bone tissue. The process of bone remodeling is highly controlled and...
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Two Weeks of Continuous Opioid Treatment in an Adenine-Induced Mouse Model of Chronic Kidney Disease Exacerbates the Bone Inflammatory State and Increases Osteoclasts
Patients with chronic kidney disease (CKD) report high pain levels, but reduced renal clearance eliminates many analgesic options; therefore, 30–50%...
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Calycosin prevents bone loss induced by hindlimb unloading
Bone loss induced by microgravity exposure seriously endangers the astronauts’ health, but its countermeasures still have certain limitations. The...