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Functional Divergence and Origin of the Vertebrate Praja Family
The Praja family is an E3 ubiquitin ligase, promoting polyubiquitination and subsequent degradation of substrates. It comprises two paralogs, praja1...
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Identification of potential microRNAs regulating metabolic plasticity and cellular phenotypes in glioblastoma
MicroRNAs (miRNAs) play important role in regulating cellular metabolism, and are currently being explored in cancer. As metabolic reprogramming in...
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MicroRNA Regulatory Network Analysis Using miRNet 2.0
MicroRNAs exert their effects in the context of gene regulatory networks. The recent development of high-throughput experimental approaches and the...
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How short are we on the goal line of estimating insect-plant interaction in a hyperdiverse tropical environment?
AbstractIn ecology, dealing with sample design is a constant challenge, especially in interaction networks, where most studies suffer from...
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Orchestrating nucleic acid–protein interactions at chromosome ends: telomerase mechanisms come into focus
Telomerase is a special reverse transcriptase ribonucleoprotein dedicated to the synthesis of telomere repeats that protect chromosome ends. Among...
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Effects of plant leaf traits, abundance and phylogeny on differentiation of herbivorous insect assemblages in Mediterranean mixed forest
Herbivorous insect assemblages are functionally diverse, with each species exploiting plant tissues in different ways. Availability and palatability...
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Pollinator visitation patterns are influenced by floral volatile profiles
Pollinators seek high quality nectar and pollen rewards critical for their growth and reproduction. Volatile emissions from inflorescences may signal...
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Growth patterns of two Red Sea mesopelagic fishes
Growth patterns and hatch-date distributions of two mesopelagic Red Sea fishes, Vinciguerria mabahiss and Maurolicus mucronatus , were inferred from...
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Development and application of a self-assembling split-fluorescent protein toolkit to monitor geminiviral movement and infection in plant
Geminiviruses are a group of circular single-stranded DNA viruses that cause severe diseases in many crop plants. However, there is still no...
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Seasonal microbial dynamics in the ocean inferred from assembled and unassembled data: a view on the unknown biosphere
In environmental metagenomic experiments, a very high proportion of the microbial sequencing data (> 70%) remains largely unexploited because rare...
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Cooling of a granular gas mixture in microgravity
Granular gases are fascinating non-equilibrium systems with interesting features such as spontaneous clustering and non-Gaussian velocity...
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Ripening dynamics revisited: an automated method to track the development of asynchronous berries on time-lapse images
BackgroundGrapevine berries undergo asynchronous growth and ripening dynamics within the same bunch. Due to the lack of efficient methods to perform...
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What is the diversity and pattern of network interactions parasite-host in amphibians (Anura) from Caatinga domain? – A meta-analysis
The first records in the literature compiled on the parasitic fauna of amphibians in Northeastern Brazil date back to the 1990s. Since then, several...
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Floral and pollinator functional diversity mediate network structure along an elevational gradient
Elevational gradients in alpine ecosystems are well suited to study how plant and pollinator communities respond to climate change. In the Austrian...
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A Deep Neural Network for Predicting Synergistic Drug Combinations on Cancer
The exploration of drug combinations presents an opportunity to amplify therapeutic effectiveness while alleviating undesirable side effects....
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MiBiOmics: an interactive web application for multi-omics data exploration and integration
BackgroundMulti-omics experimental approaches are becoming common practice in biological and medical sciences underlining the need to design new...
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GCRNN: graph convolutional recurrent neural network for compound–protein interaction prediction
BackgroundCompound–protein interaction prediction is necessary to investigate health regulatory functions and promotes drug discovery. Machine...
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Bees on the flowers of Solanum mauritianum Scop. (Solanaceae) in Southern Brazil: visitation frequency and topological networks from body and leg pollen analysis
Considering the worldwide decline of pollinators, the ecological services provided by bees have been compromised. Therefore, studying this...
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Scalable and unbiased sequence-informed embedding of single-cell ATAC-seq data with CellSpace
Standard scATAC sequencing (scATAC-seq) analysis pipelines represent cells as sparse numeric vectors relative to an atlas of peaks or genomic tiles...
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Biological Networks Analysis
Networks are widely recognized as a popular method for representing complex biological processes by capturing the interconnected relationships...