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1. Characterization of bifunctional alginate lyase Aly644 and antimicrobial activity of enzymatic hydrolysates

   Abstract

   An alginate lyase gene aly644 encoding a member of polysaccharide lyase family 6 was obtained from a metagenome of Antarctic...

   Ao Zhang, Zhe Cao, ... Tao Liu in Applied Microbiology and Biotechnology

   Article 12 September 2023
   

2. Pre-clinical evaluation of ^99mTc-labeled chalcone derivative for amyloid-β imaging post-head trauma

   Aβ ₄₂ plaque formation is one of the preliminary pathologic events that occur post traumatic brain injury (TBI) which is also among the most...

   Garima Mann, Shivani Daksh, ... Anupama Datta in JBIC Journal of Biological Inorganic Chemistry

   Article 01 March 2024
   

3. Case Study #1: Alpha Particle Therapy of Leukemia Using 225Ac-Lintuzumab

   225Ac-Lintuzumab (Actimab-A, Actinium Pharmaceuticals, Inc.) is an alpha particle emitting monoclonal antibody (mAb) drug targeting the CD33 antigen...

   Michael R. McDevitt in Radiopharmaceutical Therapy

   Chapter 2023
   

4. The Radiopharmaceutical Chemistry of Metallic Radionuclides

   Numerous metallic elements have radioisotopes with properties that are promising for radiopharmaceutical therapy. Appropriately harnessing these...

   Aohan Hu, Justin J. Wilson in Radiopharmaceutical Therapy

   Chapter 2023
   

5. Hinokitiol-iron complex is a ferroptosis inducer to inhibit triple-negative breast tumor growth

   Background

   Ferroptosis is a unique cell death, dependent on iron and phospholipid peroxidation, involved in massive processes of physiopathology....

   Hongting Zhao, Meng Zhang, ... Kuanyu Li in Cell & Bioscience

   Article Open access 13 May 2023
   

6. Integrating metabolomics and whole genome sequencing to elucidate the metabolic pathways in Methylosinus trichosporium OB3b

   Methanotrophs, relying on methane as their primary carbon source, are renowned for their exceptional capacity to generate a diverse range of...

   Dipayan Samanta, Ram N. Singh, ... Rajesh K. Sani in Systems Microbiology and Biomanufacturing

   Article 17 November 2023
   

7. Antibodies as Vectors for Radiopharmaceutical Therapy

   Monoclonal antibodies are an attractive vector for the target-specific delivery of radionuclides for radiopharmaceutical therapy (RPT) since they...

   John E. Shively, Kirstin Zettlitz, ... Jeffrey Wong in Radiopharmaceutical Therapy

   Chapter 2023
   

8. Case Study #3: Antibody Fragments in Radiopharmaceutical Therapy

   Antibodies are widely used as versatile biological tools in cancer therapeutics. In radiopharmaceutical therapy, they have been extensively exploited...

   Cyprine Neba Funeh, Parinaz Asiabi, ... Nick Devoogdt in Radiopharmaceutical Therapy

   Chapter 2023
   

9. Radiolabelling of the octadentate chelators DFO* and oxoDFO* with zirconium-89 and gallium-68

   Abstract

   In recent years, clinical imaging with zirconium-89 ( ⁸⁹ Zr)-labelled monoclonal antibodies (Ab) by positron emission tomography (immunoPET)...

   Marie Brandt, Joseph Cowell, ... Thomas L. Mindt in JBIC Journal of Biological Inorganic Chemistry

   Article 13 July 2020
   

10. A copper(II)-binding triazole derivative with ionophore properties is active against Candida spp.

    Abstract

    Invasive fungal infections (IFIs) are life threatening and existing antifungal drugs are not completely effective due to undesirable side...

    A. Gaspar-Cordeiro, S. da Silva, ... C. Pimentel in JBIC Journal of Biological Inorganic Chemistry

    Article 26 October 2020
    

11. Potential of Y. lipolytica epoxide hydrolase for efficient production of enantiopure (R)-1,2-octanediol

    The recombinant Yleh from a tropical marine yeast Yarrowia lipolytica NCIM 3589 exhibited a high epoxide hydrolase activity of 9.34 ± 1.80 µmol min ^-1 mg...

    Vijaya P. Godase, V. Ravi Kumar, Ameeta Ravi Kumar in AMB Express

    Article Open access 26 July 2023
    

12. Advancement of Radiolabeled Exosomes in Brain Disorders

    A groundbreaking nanotechnology is promised by the exosome application in brain disorder treatments due to its phenomenal characteristic of being...

    Md Jasim Uddin, Md. Faiyazuddin, ... Afra Nawar in Exosomes Based Drug Delivery Strategies for Brain Disorders

    Chapter 2024
    

13. Strategies for labelling of exogenous and endogenous extracellular vesicles and their application for in vitro and in vivo functional studies

    This review presents a comprehensive overview of labelling strategies for endogenous and exogenous extracellular vesicles, that can be utilised both...

    Marie Boudna, Andres Delgado Campos, ... Kamila Souckova in Cell Communication and Signaling

    Article Open access 09 March 2024
    

14. Comparative genomics of plant growth promoting phosphobacteria isolated from acidic soils

    Despite being one of the most abundant elements in soil, phosphorus (P) often becomes a limiting macronutrient for plants due to its low...

    Carlos Cortés-Albayay, Mabel Delgado-Torres, ... Patricio Javier Barra in Antonie van Leeuwenhoek

    Article 05 May 2024
    

15. Evidence of two differentially regulated elongasomes in Salmonella

    Cell shape is genetically inherited by all forms of life. Some unicellular microbes increase niche adaptation altering shape whereas most show...

    Sónia Castanheira, Francisco García-del Portillo in Communications Biology

    Article Open access 09 September 2023
    

16. Metal-responsive elements confer cadmium response in Arabidopsis

    Main conclusion

    Molecular, biochemical, and genetic experiments demonstrate that metal-responsive elements (MREs), initially identified in animals,...

    Chunying Wang, Ziqiang Gao, ... **aoting Qi in Planta

    Article 11 February 2023
    

17. A thermostable bacterial catalase-peroxidase oxidizes phenolic compounds derived from lignins

    Abstract

    Lignocellulosic biomass is rich in lignins, which represent a bottomless natural source of aromatic compounds. Due to the high chemical...

    Issa Fall, Quentin Czerwiec, ... Harivony Rakotoarivonina in Applied Microbiology and Biotechnology

    Article 23 November 2022
    

18. Gold drugs as colistin adjuvants in the fight against MCR-1 producing bacteria

    The emergence and rapid spread of the mobile colistin resistance gene mcr-1 among bacterial species and hosts significantly challenge the efficacy of...

    Qi Zhang, Minji Wang, ... Hongzhe Sun in JBIC Journal of Biological Inorganic Chemistry

    Article 20 January 2023
    

19. Click chemistry: a transformative technology in nuclear medicine

    The 2022 Nobel Prize in Chemistry was awarded to Professors K. Barry Sharpless, Morten Meldal and Carolyn Bertozzi for their pioneering roles in the...

    David Bauer, Samantha M. Sarrett, ... Brian M. Zeglis in Nature Protocols

    Article 26 April 2023
    

20. Assessment of bioactive peptides derived from laminin-111 as prospective breast cancer-targeting agents

    Breast cancer remains a pressing public health issue primarily affecting women. Recent research has spotlighted bioactive peptides derived from...

    Fernanda Ferreira Mendonça, Danielle Vieira Sobral, ... Luciana Malavolta in Amino Acids

    Article Open access 29 January 2024