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1. The miR-3074/BMP7 axis regulates TGF-β-caused activation of hepatic stellate cells in vitro and CCl₄-caused murine liver fibrosis in vivo

   Continuously progressive hepatic fibrosis might cause chronic liver diseases, resulting in hepatic failure. The activation of hepatic stellate cells...

   Bingjie Liu, **a **e, ... **g Liu in Human Cell

   Article 14 January 2024
   

2. Omentin-1 drives cardiomyocyte cell cycle arrest and metabolic maturation by interacting with BMP7

   Mammalian cardiomyocytes (CMs) undergo maturation during postnatal heart development to meet the increased demands of growth. Here, we found that...

   Huijun Yang, Shen Song, ... Yu Nie in Cellular and Molecular Life Sciences

   Article 21 June 2023
   

3. Repair abilities of mouse autologous adipose-derived stem cells and ShakeGel™3D complex local injection with intrauterine adhesion by BMP7-Smad5 signaling pathway activation

   Background

   The objective was to explore the therapeutic effect of autologous adipose-derived stem cells (ADSCs) combined with ShakeGel™3D...

   Yun-xia Zhao, Shao-rong Chen, ... Shu Lin in Stem Cell Research & Therapy

   Article Open access 18 March 2021
   

4. SPARCL1 promotes C2C12 cell differentiation via BMP7-mediated BMP/TGF-β cell signaling pathway

   The extracellular matrix (ECM) is known to regulate tissue development and cell morphology, movement, and differentiation. SPARCL1 is an ECM protein,...

   Yu**n Wang, ShuaiYu Liu, ... HuiLi Tong in Cell Death & Disease

   Article Open access 07 November 2019
   

5. Formation and characterization of BMP2/GDF5 and BMP4/GDF5 heterodimers

   Background

   Proteins of the TGFβ family, which are largely studied as homodimers, are also known to form heterodimers with biological activity distinct...

   Gregory R. Gipson, Kristof Nolan, ... Thomas B. Thompson in BMC Biology

   Article Open access 01 February 2023
   

6. Comparative genomic analysis of a naturally born serpentized pig reveals putative mutations related to limb and bone development

   Background

   It is believed that natural selection acts on the phenotypical changes caused by mutations. Phenotypically, from fishes to amphibians to...

   Yankai Jiang, **nyue Cao, Haibin Wang in BMC Genomics

   Article Open access 28 August 2021
   

7. Gene network analysis reveals candidate genes related with the hair follicle development in sheep

   Background

   Merino sheep are the most famous fine wool sheep in the world. They have high wool production and excellent wool quality and have attracted...

   Junmin He, Bingru Zhao, ... Kechuan Tian in BMC Genomics

   Article Open access 08 June 2022
   

8. Bone marrow NG2⁺/Nestin⁺ mesenchymal stem cells drive DTC dormancy via TGF-β2

   In the bone marrow (BM) microenvironment, where breast cancer (BC)-disseminated tumor cells (DTCs) can remain dormant for decades, NG2 ⁺ /Nestin ⁺ ...

   Ana Rita Nobre, Emma Risson, ... Julio A. Aguirre-Ghiso in Nature Cancer

   Article 11 March 2021
   

9. Hyaluronan in Kidney Fibrosis

   The kidney is the organ responsible for the regulation of the body’s fluid balance. Hyaluronan (HA), because of its unique hydration capacity, is...

   Irina Grigorieva, Emma L. Woods, ... Soma Meran in Hyaluronan

   Chapter 2023
   

10. Recent developments on BMPs and their antagonists in inflammatory bowel diseases

    Inflammatory bowel diseases (IBDs), including ulcerative colitis, and Crohn’s disease, are intestinal disorders characterized by chronic relapsing...

    Zhuo **e, Gaoshi Zhou, ... Shenghong Zhang in Cell Death Discovery

    Article Open access 01 July 2023
    

11. Insights into early ontogenesis: characterization of stress and development key genes of pikeperch (Sander lucioperca) in vivo and in vitro

    There are still numerous difficulties in the successful farming of pikeperch in the anthropogenic environment of various aquaculture systems,...

    Nadine Schäfer, Yagmur Kaya, ... Marieke Verleih in Fish Physiology and Biochemistry

    Article Open access 09 February 2021
    

12. Generation of novel in vitro flexible kidney organoid model to investigate the role of extracellular vesicles in induction of nephrogenesis

    Background

    During kidney organogenesis, metanephric mesenchyme (MM) and ureteric bud (UB) interact reciprocally to form nephrons. Signaling stimuli...

    Naveed Ahmad, Anatoliy Samoylenko, ... Seppo J Vainio in Cell Communication and Signaling

    Article Open access 18 December 2023
    

13. Population structure and selection signal analysis of indigenous sheep from the southern edge of the Taklamakan Desert

    Analyzing the genetic diversity and selection characteristics of sheep (Ovis aries) holds significant value in understanding their environmental...

    Zhi-peng Han, Rui-zhi Yang, ... Shu-dong Liu in BMC Genomics

    Article Open access 09 July 2024
    

14. The roles and regulatory mechanisms of TGF-β and BMP signaling in bone and cartilage development, homeostasis and disease

    Transforming growth factor-βs (TGF-βs) and bone morphometric proteins (BMPs) belong to the TGF-β superfamily and perform essential functions during...

    Mengrui Wu, Shali Wu, ... Yi-** Li in Cell Research

    Article Open access 24 January 2024
    

15. Romidepsin hepatocellular carcinoma suppression in mice is associated with deregulated gene expression of bone morphogenetic protein and Notch signaling pathway components

    Recently, our group showed that Romidepsin, a histone deacetylase inhibitor (HDACi), suppressed diethylnitrosamine (DEN)-induced hepatocellular...

    Hara Afaloniati, Theofilos Poutahidis, ... Katerina Angelopoulou in Molecular Biology Reports

    Article 03 January 2021
    

16. Ablation of Fam20c causes amelogenesis imperfecta via inhibiting Smad dependent BMP signaling pathway

    Background

    Amelogenesis imperfecta (AI) is a type of hereditary diseases that manifest defects in the formation or mineralization of enamel. Recently,...

    **g Liu, Wuliji Saiyin, ... Lili Li in Biology Direct

    Article Open access 07 October 2020
    

17. Evolutionary genetics of flipper forelimb and hindlimb loss from limb development-related genes in cetaceans

    Background

    Cetacean hindlimbs were lost and their forelimb changed into flippers characterized by webbed digits and hyperphalangy, thus allowing them...

    Linxia Sun, **nghua Rong, ... Shixia Xu in BMC Genomics

    Article Open access 02 December 2022
    

18. Transcriptome Analysis of Signaling Pathways in Caco-2 Cells Involved in the Formation of Intestinal Villi

    Caco-2 cells are traditionally used to construct in vitro models of the intestinal barrier. One characteristic of the mature intestine is the...

    S. V. Nikulin, M. P. Raigorodskaya, D. A. Sakharov in Applied Biochemistry and Microbiology

    Article 01 December 2020
    

19. Mesenchymal Stem Cell-based Scaffolds in Regenerative Medicine of Dental Diseases

    Biomedical engineering breakthroughs and increased patient expectations and requests for more comprehensive care are propelling the field of...

    Mohammad Kiarashi, Hannaneh Bayat, ... Saman Yasamineh in Stem Cell Reviews and Reports

    Article 03 February 2024
    

20. BMP signaling in cancer stemness and differentiation

    The BMP (Bone morphogenetic protein) signaling pathway plays a central role in metazoan biology, intricately sha** embryonic development,...

    Wei Zhou, Kun Yan, Qiaoran ** in Cell Regeneration

    Article Open access 05 December 2023