Search
Search Results
-
Insights into the C-terminal domain of apolipoprotein E from chimera studies with apolipophorin III
Apolipoprotein E3 (apoE) is a critical cholesterol transport protein in humans and is composed of two domains: a well characterized N-terminal (NT)...
-
An improved method for estimating low LDL-C based on the enhanced Sampson-NIH equation
BackgroundThe accurate measurement of Low-density lipoprotein cholesterol (LDL-C) is critical in the decision to utilize the new lipid-lowering...
-
The mitochondrial BCKD complex interacts with hepatic apolipoprotein E in cultured cells in vitro and mouse livers in vivo
Background and aimsApolipoprotein E (APOE) is known for its role in lipid metabolism and its association with age-related disease pathology. The aim...
-
Apolipoprotein B and renal function: across-sectional study from the China health and nutrition survey
BackgroundChronic kidney disease (CKD) is a worldwide public health problem characterized by changes in kidney structure and function, usually...
-
The extended lipid panel assay: a clinically-deployed high-throughput nuclear magnetic resonance method for the simultaneous measurement of lipids and Apolipoprotein B
BackgroundStandard lipid panel assays employing chemical/enzymatic methods measure total cholesterol (TC), triglycerides (TG), and high-density...
-
Effects of Cortisol and Tetrahydrocortisol on the Secondary Structure of Apolipoprotein A-I as Measured by Fourier Transform Infrared Spectroscopy
Abstract—The interaction of the steroid hormone cortisol and its metabolite tetrahydrocortisol (THC) with two serum proteins, apolipoprotein AI...
-
The cholesterol-lowering effect of unripe Rubus coreanus is associated with decreased oxidized LDL and apolipoprotein B levels in subjects with borderline-high cholesterol levels: a randomized controlled trial
BackgroundRubus coreanus ( R. coreanus ) possesses properties that may decrease cholesterol levels.
MethodsThe effects of unripe R. coreanus (uRC)...
-
High-density lipoprotein cholesterol efflux capacity in patients with obstructive sleep apnea and its relation with disease severity
BackgroundObstructive sleep apnea (OSA) is linked to an accelerated risk of cardiovascular disease (CVD). Some key CVD risk factors are present in...
-
Effect of sacubitril/valsartan on lipid metabolism in patients with chronic kidney disease combined with chronic heart failure: a retrospective study
Background and objectiveDyslipidemia is significantly more common in those with concurrent chronic kidney disease (CKD) and chronic heart failure...
-
Effects of weight change on apolipoprotein B-containing emerging atherosclerotic cardiovascular disease (ASCVD) risk factors
Background and aimsNon-high-density (HDL)-cholesterol, low-density lipoprotein (LDL)-particle number, apolipoprotein B, lipoprotein(a) (Lp(a)), and...
-
Association between Apo B, LDL-R and PCSK9 gene polymorphisms with coronary artery diseases in Egyptians
BackgroundMany studies have focused on the significance of lipid regulatory genes in the pathophysiology of Coronary artery disease (CAD). ApoB XbaI...
-
The Antibacterial Effect of Ciprofloxacin Loaded Calcium Carbonate (CaCO3) Nanoparticles Against the Common Bacterial Agents of Osteomyelitis
The present study aimed to investigate the biocompatibility, antibacterial/anti-biofilm effects of ciprofloxacin-loaded calcium carbonate (Cip-...
-
Proteomic insights into the pathophysiology of hypertension-associated albuminuria: Pilot study in a South African cohort
BackgroundHypertension is an important public health priority with a high prevalence in Africa. It is also an independent risk factor for kidney...
-
LDLR and PCSK9 3´UTR variants and their putative effects on microRNA molecular interactions in familial hypercholesterolemia: a computational approach
BackgroundFamilial hypercholesterolemia (FH) is caused by pathogenic variants in low-density lipoprotein (LDL) receptor ( LDLR ) or its associated...
-
Serum lipid profile in relation to free thyroxine and the effect of levothyroxine treatment on lipids in patients with isolated hypothyroxinemia during pregnancy: a single-center retrospective study
BackgroundThyroid function is widely considered a lipid metabolism regulator. However, studies on lipid metabolism in pregnant women with low free...
-
Apolipoprotein B/apolipoprotein A1 ratio and mortality among incident peritoneal dialysis patients
BackgroundTo investigate the association between the ratio of apolipoprotein B (apo B) / apolipoprotein A1 (apo A1) with all-cause mortality and...
-
Structure–function analysis of naturally occurring apolipoprotein A-I L144R, A164S and L178P mutants provides insight on their role on HDL levels and cardiovascular risk
Naturally occurring point mutations in apolipoprotein A-I (apoA-I), the major protein component of high-density lipoprotein (HDL), may affect plasma...
-
Apolipoprotein E gene polymorphism and renal function are associated with apolipoprotein E concentration in patients with chronic kidney disease
BackgroundChronic kidney disease (CKD) associates with complex lipoprotein disturbances resulting in high cardiovascular risk. Apolipoprotein E...
-
Isolation of Extracellular Vesicles Using Titanium Dioxide Microspheres
Extracellular vesicles (EVs) are bilayer membrane particles released from several cell types to the extracellular environment. EVs have a crucial...
-
Preprocedural Lp(a) level and ApoB/ApoA-Ι ratio and the risk for contrast-induced acute kidney injury in patients undergoing emergency PCI
BackgroundHigh serum Lipoprotein(a) (Lp(a)) level and Apolipoprotein B/Apolipoprotein AΙ (ApoB/ApoA-Ι) ratio are risk factors for cardiovascular...
